Human PALM Recombinant Protein – Cat# MBS1259184

Paralemmin-1 (PALM) Human Recombinant Protein

Name: PALM Recombinant Protein; Paralemmin-1; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1259184
Price: 315 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1259184

Involved in plasma membrane dynamics and cell process formation. Isoform 1 and isoform 2 are necessary for axonal and dendritic filopodia induction, for dendritic spine maturation and synapse formation in a palmitoylation-dependent manner. More details

$315 / 0.02 mg (E-Coli) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Paralemmin-1 (PALM), Recombinant Protein

Full Product Name

Recombinant Human Paralemmin-1 (PALM)

Product Gene Name

PALM recombinant protein

Product Synonym Gene Name

PALM; KIAA0270

Product Synonym Names

Paralemmin-1; Paralemmin

Sequence

MEVLAAETTS QQERLQAIAE KRKRQAEIEN KRRQLEDERR QLQHLKSKAL RERWLLEGTP SSASEGDEDL RRQMQDDEQK TRLLEDSVSR LEKEIEVLER GDSAPATAKE NAAAPSPVRA PAPSPAKEER KTEVVMNSQQ TPVGTPKDKR VSNTPLRTVD GSPMMKAAMY SVEITVEKDK VTGETRVLSS TTLLPRQPLP LGIKVYEDET KVVHAVDGTA ENGIHPLSSS EVDELIHKAD EVTLSEAGST AGAAETRGAV EGAARTTPSR REITGVQAQP GEATSGPPGI QPGQEPPVTM IFMGYQNVED EAETKKVLGL QDTITAELVV IEDAAEPKEP APPNGSAAEP PTEAASREEN QAGPEATTSD PQDLDMKKHR CKCC

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Molecular Weight

45.7 kDa

Sequence Positions

1-384aa; Full Length

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

OMIM

608134

3D Structure

ModBase 3D Structure for O75781

Species

Homo sapiens (Human)

Product Categories/Family for PALM recombinant protein

Neuroscience

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PALM recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PALM purchase

MBS1259184 is a recombinant protein targeting PALM. Also known as Recombinant Human Paralemmin-1 (PALM). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for PALM. It may not necessarily be applicable to this product.

NCBI GI #

93141029

NCBI GeneID

5064

NCBI Accession #

NP_001035224.1

UniProt Primary Accession #

O75781

UniProt Secondary Accession #

O43359; O95673; Q92559; Q9UPJ4; Q9UQS2; Q9UQS3

UniProt Related Accession #

O75781

GenBank Nucleotide #

NM_001040134.1

NCBI Official Full Name

paralemmin-1 isoform 2

NCBI Official Synonym Full Names

paralemmin

NCBI Official Symbol

PALM

UniProt Protein Name

Paralemmin-1

UniProt Synonym Protein Names

Paralemmin

Protein Family

Paralemmin

UniProt Gene Name

PALM

UniProt Synonym Gene Names

KIAA0270

UniProt Entry Name

PALM_HUMAN

NCBI Protein Information

paralemmin-1

NCBI Summary for PALM

This gene encodes a member of the paralemmin protein family. The product of this gene is a prenylated and palmitoylated phosphoprotein that associates with the cytoplasmic face of plasma membranes and is implicated in plasma membrane dynamics in neurons and other cell types. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008]

UniProt Comments for PALM

paralemmin: Involved in plasma membrane dynamics and cell process formation. Isoform 1 and isoform 2 are necessary for axonal and dendritic filopodia induction, for dendritic spine maturation and synapse formation in a palmitoylation-dependent manner. Belongs to the paralemmin family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: nucleoplasm; filopodium membrane; intracellular membrane-bound organelle; axon; integral to plasma membrane; apicolateral plasma membrane; basolateral plasma membrane; cytoplasmic membrane-bound vesicle; plasma membrane; nucleus

Molecular Function: protein binding; D3 dopamine receptor binding

Biological Process: positive regulation of filopodium formation; regulation of cell shape; synapse maturation; negative regulation of dopamine receptor signaling pathway; negative regulation of adenylate cyclase activity; cytoskeleton organization and biogenesis; cell motility

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PALM recombinant protein

Reference Product	PubMed Publications
USP7 recombinant protein	>1 publications with PALM and USP7
AKAP2 recombinant protein	>1 publications with PALM and AKAP2

Diseases associated with PALM recombinant protein

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>573 publications with PALM and Cardiovascular Diseases
Congenital Abnormalities Antibodies	>198 publications with PALM and Congenital Abnormalities
Fatty Liver Antibodies	>190 publications with PALM and Fatty Liver
Disease Models, Animal Antibodies	>164 publications with PALM and Disease Models, Animal
Inflammation Antibodies	>152 publications with PALM and Inflammation
Necrosis Antibodies	>139 publications with PALM and Necrosis
Liver Diseases Antibodies	>118 publications with PALM and Liver Diseases
Body Weight Changes Antibodies	>104 publications with PALM and Body Weight Changes
Weight Gain Antibodies	>104 publications with PALM and Weight Gain
Kidney Diseases Antibodies	>87 publications with PALM and Kidney Diseases

Organs/Tissues associated with PALM recombinant protein

Organ/Tissue Name	Pubmed Publications
Skin Antibodies	>1282 publications with PALM and Skin
Nerve Antibodies	>676 publications with PALM and Nerve
Muscle Antibodies	>648 publications with PALM and Muscle
Brain Antibodies	>610 publications with PALM and Brain
Bone Antibodies	>449 publications with PALM and Bone
Liver Antibodies	>423 publications with PALM and Liver
Eye Antibodies	>212 publications with PALM and Eye
Kidney Antibodies	>210 publications with PALM and Kidney
Adipose Tissue Antibodies	>131 publications with PALM and Adipose Tissue
Mouth Antibodies	>124 publications with PALM and Mouth