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Acetylcholine Receptor Subunit Epsilon (chrne) Xenopus Laevis Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1260781

MBS1260781 is a recombinant protein targeting chrne. Also known as Recombinant Xenopus laevis Acetylcholine receptor subunit epsilon (chrne). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Acetylcholine receptor subunit epsilon (chrne), Recombinant Protein
Full Product Name
Recombinant Xenopus laevis Acetylcholine receptor subunit epsilon (chrne)
Product Gene Name
chrne recombinant protein
Product Synonym Gene Name
chrne
Product Synonym Names
Recombinant Acetylcholine receptor subunit epsilon (chrne); Acetylcholine receptor subunit epsilon
Sequence
SESEESRLIK HLFTSYDQKA RPSKGLDDVV PVTLKLTLTN LIDLNEKEET LTTNVWVQIA WNDDRLVWNV TDYGGIGFVP VPHDIMWLPD IVLENNIDGN FEVAYYANVL VYNTGYIYWL PPAIFRSTCN IEITYFPFDW QNCSLVFRSK TYSANEIDLQ LVTDDETGLP FDQVDIDREA FTENGEWAIM HRPARKILNP KYSKEDLRYQ EIVFNLIIQR KPLFYIINII VPCVLISFLV VLVYFLPAKA GGQKCTVSIS VLLAQTVFLF LIAQMVPETS LSVPLIGKYL MFVMFVSTLI VLSCVIVLNV SLRSPSTHNL STKVKHMLLE VLPQFLHLRV EPCDEGEETP RERRRSSLGI MLKAEEYVLK KPRSELMFER QRERHGMRRE PDGYRADGFD VGVTTTLYRN LAQCAPEIKD CVDACNFITQ NTKEQNRTGS EMENWILIGK VLDVLCFWVA LPLFVLGTLA IFLMGHFNTA PEHPF
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Molecular Weight
57,788 Da
Sequence Positions
20-504
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for P49580
Species
Xenopus laevis (African clawed frog)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of chrne recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for chrne. It may not necessarily be applicable to this product.

NCBI GI #
148227704
NCBI GeneID
386670
NCBI Accession #
NP_001080916.1
UniProt Primary Accession #
P49580
UniProt Related Accession #
P49580
GenBank Nucleotide #
NM_001087447.1
NCBI Official Full Name
acetylcholine receptor subunit epsilon
NCBI Official Synonym Full Names
cholinergic receptor, nicotinic, epsilon (muscle)<
NCBI Official Symbol
chrne
UniProt Protein Name
Acetylcholine receptor subunit epsilon
Protein Family
Acetylcholine receptor
UniProt Gene Name
chrne
UniProt Entry Name
ACHE_XENLA
NCBI Protein Information
acetylcholine receptor subunit epsilon; nicotinic acetylcholine receptor epsilon subunit

UniProt Comments for chrne

Function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

Subunit structure: Pentamer of two alpha chains, and one each of the beta, delta, and gamma (in immature muscle) or epsilon (in mature muscle) chains.

Subcellular location: Cell junction › synapse › postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Sequence similarities: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Epsilon/CHRNE sub-subfamily. [View classification]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with chrne recombinant protein

 Products by Pathway  Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram

Diseases associated with chrne recombinant protein

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >31 publications with chrne and Nervous System Diseases
 Disease Models, Animal Antibodies  >3 publications with chrne and Disease Models, Animal
 Myasthenic Syndrome, Congenital, Fast-Channel Antibodies  >3 publications with chrne and Myasthenic Syndrome, Congenital, Fast-Channel
 MYASTHENIC SYNDROME, CONGENITAL, ASSOCIATED WITH ACETYLCHOLINE RECEPTOR DEFICIENCY Antibodies  >2 publications with chrne and MYASTHENIC SYNDROME, CONGENITAL, ASSOCIATED WITH ACETYLCHOLINE RECEPTOR DEFICIENCY
 Death Antibodies  >1 publications with chrne and Death
 Myasthenic syndrome, congenital, postsynaptic slow-channel Antibodies  >1 publications with chrne and Myasthenic syndrome, congenital, postsynaptic slow-channel
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