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Integrin Alpha-PS3 (scb) Drosophila Melanogaster Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1261029

MBS1261029 is a recombinant protein targeting scb. Also known as Recombinant Drosophila melanogaster Integrin alpha-PS3 (scb), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Integrin alpha-PS3 (scb), Recombinant Protein
Full Product Name
Recombinant Drosophila melanogaster Integrin alpha-PS3 (scb), partial
Product Gene Name
scb recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
124,336 Da
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for O44386
Species
Drosophila melanogaster (Fruit fly)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of scb recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for scb. It may not necessarily be applicable to this product.

NCBI GI #
24653808
NCBI GeneID
36692
NCBI Accession #
NP_523750.2
UniProt Primary Accession #
O44386
UniProt Secondary Accession #
O44387; O46186; Q58CK3; Q6AWK3; Q9V7A3
UniProt Related Accession #
O44386
GenBank Nucleotide #
NM_079026.3
NCBI Official Full Name
scab, isoform B
NCBI Official Synonym Full Names
scab
NCBI Official Symbol
scb
NCBI Official Synonym Symbols
alpha-PS3; alphaInt3; alphaPS3; alpha[[PS3]]; aPS3; beta[[PS3]; CG8095; CT21280; CT36929; Dm0620; DmelCG8095; E(Sev-CycE)E93; E(sev-cycE)[e93]; ItgaPS3; l(2)01288; PS3; vol; Vol
UniProt Protein Name
Integrin alpha-PS3
UniProt Synonym Protein Names
Position-specific antigen subunit alpha-3; Protein scab
Protein Family
Integrin
UniProt Gene Name
scb
UniProt Synonym Gene Names
alphaPS3; Vol; Protein scab
NCBI Protein Information
CG8095 gene product from transcript CG8095-RB

UniProt Comments for scb

Integrin alpha-PS3/beta-PS is a receptor for laminin. Also binds to wb. Important during embryogenesis for the development of the trachea, dorsal vessel and salivary gland, as well as for dorsal closure. Required for short-term memory processes. Minor involvement in the establishment of the oocyte anterior-posterior length. Plays a role in timely border cell migration during oogenesis, probably mediated by JNK signaling. Integrin alpha-PS3/Itgbn is required for effective phagocytosis of apoptotic cells during embryonic development and for the phagocytic elimination of S.aureus by mediating the binding of S.aureus peptidoglycan to larval hemocytes, which probably activates a signaling pathway involving Rac1 and Rac2. Integrin alpha-PS3/Itgbn also regulates Fak activity during neuromuscular junction (NMJ) growth and is required for its activation in presynapsis of NMJs. Seems to be dispensable for major morphogenetic processes.
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Research Articles on scb

1. the integrin heterodimer alphaPS3/betaPS becomes apically enriched and is required for engulfment by the epithelial follicle cells of the Drosophila ovary.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with scb recombinant protein

 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 L1CAM Interactions Pathway antibodies  L1CAM Interactions Pathway Diagram
 Signal Transduction By L1 Pathway antibodies  Signal Transduction By L1 Pathway Diagram

Organs/Tissues associated with scb recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Gonad Antibodies  >2 publications with scb and Gonad
 Whole Body Antibodies  >1 publications with scb and Whole Body
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