Squalus Acanthias KCNQ1 Recombinant Protein – Cat# MBS1261467

Potassium Voltage-Gated Channel Subfamily KQT Member 1 (KCNQ1) Squalus Acanthias Recombinant Protein

Name: KCNQ1 Recombinant Protein; Squalus Acanthias; MyBioSource
Brand: MyBioSource
SKU: MBS1261467
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1261467

MBS1261467 is a recombinant protein targeting KCNQ1. Also known as Recombinant Squalus acanthias Potassium voltage-gated channel subfamily KQT member 1 (KCNQ1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Potassium voltage-gated channel subfamily KQT member 1 (KCNQ1), Recombinant Protein

Full Product Name

Recombinant Squalus acanthias Potassium voltage-gated channel subfamily KQT member 1 (KCNQ1)

Product Gene Name

KCNQ1 recombinant protein

Product Synonym Gene Name

KCNQ1

Product Synonym Names

Recombinant Potassium voltage-gated channel subfamily KQT member 1 (KCNQ1); Potassium voltage-gated channel subfamily KQT member 1; IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1 KQT-like 1 Voltage-gated potassium channel subunit

Sequence

MSSEVKSRWS GSGSQKSGTA RKPTMLEMAE NAASRHYEPV PLPLQRSNSP DSSTDKNPES RAADSRAEVI INPDIPPKAI ALPLSRYRGR NPFFSKVNIQ GRTYNFLERP TGWKCFIYHF TVFLIVLVCL IFSVMSTIEQ YHYFANRALV WMEIVLVVFF GTEYIVRLWS AGCRSKYVGF WGRLRFARKP ISIIDLIVVV ASVIVLCVGS NGQVFATSAI RGIRFLQILR MLHVDRQGGT WRLLGSVVFI HRQELITTLY IGFLGLIFSS YFVYLAEKDA VDDSGSQQFG SYADALWWGV VTVTTIGYGD KVPQTWIGRT IASCFSVFAI SFFALPAGIL GSGFALKVQQ KQRQKHFNRQ IPAAASLIQT SWRCHAAENH ESATWKMYVR QPTKFYVASP SPKTKKSVGK RKKLKTDKDN GLNSEKSLNV PNITYDHVVD KDDRKFENSN IDGYDSSVKK SLGILDVNSG ALSRANSYAD DLDFIEGEPV LAPITHVSQL RESHRVTVKV IRRMQYFVAK KKFQQARKPY DVRDVIEQYS QGHLNLMVRI KELQRRLDQS LGKPTMFLSV SEKSQDRGKN TIGARLNRVE EKFVHMDQKL NTITDMLHHL VAHQQGHPHP QTQPQAQGTV VQAVASTHSS LPSYEQLTVR RKDQDNQPDL

Host

E Coli or Yeast or Baculovirus or Mammalian Cell

Form/Format

Lyophilized or liquid (Format to be determined during the manufacturing process)

Purity/Purification

Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)

Preparation and Storage

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Molecular Weight

74,687 Da

Sequence Positions

1-660

Tag Information

This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.

Sterility

Sterile filter available upon request.

Endotoxin

Low endotoxin available upon request.

3D Structure

ModBase 3D Structure for O73925

Species

Squalus acanthias (Spiny dogfish)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of KCNQ1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for KCNQ1. It may not necessarily be applicable to this product.

NCBI GI #

14285391

NCBI Accession #

O73925.1

UniProt Primary Accession #

O73925

NCBI Official Full Name

Potassium voltage-gated channel subfamily KQT member 1

UniProt Protein Name

Potassium voltage-gated channel subfamily KQT member 1

UniProt Synonym Protein Names

IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1; KQT-like 1; Voltage-gated potassium channel subunit Kv7.1

Protein Family

Potassium voltage-gated channel subfamily

UniProt Gene Name

KCNQ1

UniProt Entry Name

KCNQ1_SQUAC

UniProt Comments for KCNQ1

Function: Probably important in cardiac repolarization. Associates with KCNE1 (MinK) to form the I(Ks) cardiac potassium current. Elicits a rapidly activating, potassium-selective outward current. Is also a potential candidate responsible for the basolateral potassium conductance of secretory epithelia.

Subunit structure: Heterotetramer with KCNE1 (MinK) or KCNE3 (MiRP2). Interacts with CALM

By similarity.

Subcellular location: Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein

By similarity.

Tissue specificity: Expressed only in rectal gland and heart. Faintly expressed in intestine. Undetectable in kidney, brain, testis, liver and gills.

Domain: The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position

By similarity.

Sequence similarities: Belongs to the potassium channel family. KQT (TC 1.A.1.15) subfamily. Kv7.1/KCNQ1 sub-subfamily. [View classification]

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with KCNQ1 recombinant protein

Reference Product	PubMed Publications
FLNA recombinant protein	>12 publications with KCNQ1 and FLNA

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