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HSPA1L Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS126498
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This gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HSPA1L, Polyclonal Antibody
Full Product Name
HSPA1L Polyclonal Antibody
Product Gene Name
anti-HSPA1L antibody
Product Synonym Names
HSP70T; hum70t; HSP70-1L; HSP70-HOM
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
641
OMIM
140559
3D Structure
ModBase 3D Structure for P34931
Species
Human
Immunogen
Recombinant protein of human HSPA1L
Calculated Molecular Weight
70kDa

Product Categories/Family for anti-HSPA1L antibody

Polyclonal
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-HSPA1L antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-HSPA1L antibody
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200

Western Blot (WB) of anti-HSPA1L antibody

Western blot analysis of extracts of various cell lines, using HSPA1L antibody at 1:500 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Rabbit Anti-HSPA1L Polyclonal Antibody – Cat# MBS126498

Immunofluorescence (IF) of anti-HSPA1L antibody

Immunofluorescence analysis of U2OS cells using HSPA1L antibody. Blue: DAPI for nuclear staining.
Rabbit Anti-HSPA1L Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS126498

Other Notes

Small volumes of anti-HSPA1L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HSPA1L purchase

MBS126498 is an antibody targeting HSPA1L. Also known as HSPA1L Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HSPA1L. It may not necessarily be applicable to this product.

NCBI GI #
23831140
NCBI GeneID
3305
NCBI Accession #
P34931.2
UniProt Primary Accession #
P34931
UniProt Secondary Accession #
O75634; Q2HXR3; Q8NE72; Q96QC9; Q9UQM1; A6NNB0; B0UXW8
UniProt Related Accession #
P34931
NCBI Official Full Name
Heat shock 70 kDa protein 1-like
NCBI Official Synonym Full Names
heat shock 70kDa protein 1-like
NCBI Official Symbol
HSPA1L
NCBI Official Synonym Symbols
HSP70T; hum70t; HSP70-1L; HSP70-HOM
UniProt Protein Name
Heat shock 70 kDa protein 1-like
UniProt Synonym Protein Names
Heat shock 70 kDa protein 1-Hom; HSP70-Hom
Protein Family
Heat shock 70 kDa protein
UniProt Gene Name
HSPA1L
UniProt Synonym Gene Names
Heat shock 70 kDa protein 1L; HSP70-Hom
UniProt Entry Name
HS71L_HUMAN
NCBI Protein Information
heat shock 70 kDa protein 1-like; heat shock 70 kDa protein 1L; heat shock 70kD protein-like 1; heat shock 10kDa protein 1-like; heat shock 70 kDa protein 1-Hom

UniProt Comments for HSPA1L

HSPA1L: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. Not induced by heat shock. Expressed in spermatids. Belongs to the heat shock protein 70 family.

Protein type: Heat shock protein; Mitochondrial; Chaperone

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: signalosome; nucleoplasm; mitochondrial matrix; cytosol

Molecular Function: protein binding; unfolded protein binding; ATP binding

Biological Process: binding of sperm to zona pellucida; protein refolding; response to unfolded protein
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Research Articles on HSPA1L

1. The potential implication of HSPA1A +190G/C, HSPA1B +1267A/G, and HSPA1L +2437T/C polymorphisms in the susceptibility to paranoid schizophrenia in a homogenous Caucasian Polish population, was analyzed.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-HSPA1L antibody

 Products by Pathway  Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Attenuation Phase Pathway antibodies  Attenuation Phase Pathway Diagram
 Cellular Response To Heat Stress Pathway antibodies  Cellular Response To Heat Stress Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Estrogen Signaling Pathway antibodies  Estrogen Signaling Pathway Diagram

Diseases associated with anti-HSPA1L antibody

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >6 publications with HSPA1L and Cardiovascular Diseases
 Necrosis Antibodies  >6 publications with HSPA1L and Necrosis
 Inflammation Antibodies  >3 publications with HSPA1L and Inflammation
 Drug-Related Side Effects and Adverse Reactions Antibodies  >3 publications with HSPA1L and Drug-Related Side Effects and Adverse Reactions
 Lung Diseases Antibodies  >3 publications with HSPA1L and Lung Diseases
 Drug Hypersensitivity Antibodies  >3 publications with HSPA1L and Drug Hypersensitivity
 Heart Diseases Antibodies  >2 publications with HSPA1L and Heart Diseases
 Nervous System Diseases Antibodies  >2 publications with HSPA1L and Nervous System Diseases
 Liver Diseases Antibodies  >2 publications with HSPA1L and Liver Diseases
 Liver Neoplasms Antibodies  >2 publications with HSPA1L and Liver Neoplasms

Organs/Tissues associated with anti-HSPA1L antibody

 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >2 publications with HSPA1L and Testis
 Kidney Antibodies  >1 publications with HSPA1L and Kidney
 Lung Antibodies  >1 publications with HSPA1L and Lung
 Eye Antibodies  >1 publications with HSPA1L and Eye
 Connective Tissue Antibodies  >1 publications with HSPA1L and Connective Tissue
 Brain Antibodies  >1 publications with HSPA1L and Brain
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