GTP Cyclohydrolase-2 (GTP) E Coli Recombinant Protein

Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

Biosynthesis of riboflavin cloning, sequencing, mapping, and expression of the gene coding for GTP cyclohydrolase II in Escherichia coli.Richter G., Ritz H., Katzenmeier G., Volk R., Kohnle A., Lottspeich F., Allendorf D., Bacher A.J. Bacteriol. 175:4045-4051(1993) A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map.Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T., Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S., Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y., Wada C., Yamamoto Y., Horiuchi T.DNA Res. 3:363-377(1996) The complete genome sequence of Escherichia coli K-12.Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.Science 277:1453-1462(1997) Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.Mol. Syst. Biol. 2:E1-E5(2006) The aconitase of Escherichia coli. Nucleotide sequence of the aconitase gene and amino acid sequence similarity with mitochondrial aconitases, the iron-responsive-element-binding protein and isopropylmalate isomerases.Prodromou C., Artymiuk P.J., Guest J.R.Eur. J. Biochem. 204:599-609(1992) Purification and properties of guanosine triphosphate cyclohydrolase II from Escherichia coli.Foor F., Brown G.M.J. Biol. Chem. 250:3545-3551(1975) Biosynthesis of riboflavin studies on the mechanism of GTP cyclohydrolase II.Ritz H., Schramek N., Bracher A., Herz S., Eisenreich W., Richter G., Bacher A.J. Biol. Chem. 276:22273-22277(2001) Biosynthesis of vitamin B2.Kaiser J., Schramek N., Eberhardt S., Puettmer S., Schuster M., Bacher A.Eur. J. Biochem. 269:5264-5270(2002) GTP cyclohydrolase II structure and mechanism.Ren J., Kotaka M., Lockyer M., Lamb H.K., Hawkins A.R., Stammers D.K.J. Biol. Chem. 280:36912-36919(2005)

Small volumes of GTP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS1265364 is a recombinant protein targeting GTP. Also known as Recombinant E Coli GTP cyclohydrolase-2. Host: E Coli.