C-C Motif Chemokine 9 (CCL9) Mouse Recombinant Protein

Monokine with inflammatory, pyrogenic and chokinetic properties. Circulates at high concentrations in the blood of healthy animals. Binding to a high-affinity receptor activates calcium release in neutrophils. It also inhibits colony formation of bone marrow myeloid immature progenitors.

MIP-1 gamma molecular cloning, expression, and biological activities of a novel CC chemokine that is constitutively secreted in vivo.Poltorak A.N., Bazzoni F., Smirnova I.I., Alejos E., Thompson P., Luheshi G., Rothwell N., Beutler B.J. Inflamm. 45:207-219(1995) A novel chemokine, macrophage inflammatory protein-related protein-2, inhibits colony formation of bone marrow myeloid progenitors.Youn B.-S., Jang I.-K., Broxmeyer H.E., Cooper S., Jenkins N.A., Gilbert D.J., Copeland N.G., Elick T.A., Fraser M.J. Jr., Kwon B.S.J. Immunol. 155:2661-2667(1995) Molecular cloning and functional characterization of a novel member of the C-C chemokine family.Hara T., Bacon K.B., Cho L.C., Yoshimura A., Morikawa Y., Copeland N.G., Gilbert D.J., Jenkins N.A., Schall T.J., Miyajima A.J. Immunol. 155:5352-5358(1995) Sequence polymorphisms in the chemokines Scya1 (TCA-3) , Scya2 (monocyte chemoattractant protein (MCP) -1) , and Scya12 (MCP-5) are candidates for eae7, a locus controlling susceptibility to monophasic remitting/nonrelapsing experimental allergic encephalomyelitis.Teuscher C., Butterfield R.J., Ma R.Z., Zachary J.F., Doerge R.W., Blankenhorn E.P.J. Immunol. 163:2262-2266(1999) Organization of the mouse CC chemokine cluster containing the genes for C10, MRP-2 and RANTES.Nomiyama H. Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.PLoS Biol. 7:E1000112-E1000112(2009) Proteolytic activation of alternative CCR1 ligands in inflammation.Berahovich R.D., Miao Z., Wang Y., Premack B., Howard M.C., Schall T.J.J. Immunol. 174:7341-7351(2005)

Small volumes of Ccl9 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS1265436 is a recombinant protein targeting Ccl9. Also known as Recombinant Mouse C-C motif chemokine 9. Host: E Coli.