Brain-Derived Neurotrophic Factor (BDNF) Rat Recombinant Protein

During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.

Human and rat brain-derived neurotrophic factor and neurotrophin-3 gene structures, distributions, and chromosomal localizations.Maisonpierre P.C., le Beau M.M., Espinosa R. III, Ip N.Y., Belluscio L., de la Monte S.M., Squinto S., Furth M.E., Yancopoulos G.D.Genomics 10:558-568(1991) A rat brain-derived neurotrophic factor-encoding gene generates multiple transcripts through alternative use of 5' exons and polyadenylation sites.Ohara O., Gahara Y., Teraoka H., Kitamura T.Gene 121:383-386(1992) Neurotrophic factors, their receptors, and the signal transduction pathways they activate.Yancopoulos G.D., Maisonpierre P.C., Ip N.Y., Aldrich T.H., Belluscio L., Boulton T.G., Cobb M.H., Squinto S.P., Furth M.E.Cold Spring Harb. Symp. Quant. Biol. 55:371-379(1990) Rodent BDNF genes, novel promoters, novel splice variants, and regulation by cocaine.Liu Q.-R., Lu L., Zhu X.-G., Gong J.-P., Shaham Y., Uhl G.R.Brain Res. 1067:1-12(2006) Mouse and rat BDNF gene structure and expression revisited.Aid T., Kazantseva A., Piirsoo M., Palm K., Timmusk T.J. Neurosci. Res. 85:525-535(2007) Reconstituting BDNF gene to bone marrow mesenchymal stem cells serving as portals in the therapy of Parkinson's disease.Zhao L.X., Zhang J., Wang D.M., Yu X.J., Yue W., Pei X.T., Xu X.H. Multiple promoters direct tissue-specific expression of the rat BDNF gene.Timmusk T., Palm K., Metsis M., Reintam T., Palme V., Saarma M., Persson H.Neuron 10:475-489(1993) Evolutionary studies of the nerve growth factor family reveal a novel member abundantly expressed in Xenopus ovary.Hallboeoek F., Ibanez C.F., Persson H.Neuron 6:845-858(1991)

Small volumes of Bdnf recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS1265509 is a recombinant protein targeting Bdnf. Also known as Recombinant Rat Brain-derived neurotrophic factor (Bdnf), partial. Host: E Coli.