Rabbit Anti-SOX8 Polyclonal Antibody – Cat# MBS126880

Western blot analysis of extracts of SK-BR-3 cells, using SOX8 antibody.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.

SOX8 Antibody – Rabbit Polyclonal

Name: SOX8 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS126880
Price: 360 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS126880

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

SOX8, Polyclonal Antibody

Full Product Name

SOX8 Polyclonal Antibody

Product Gene Name

anti-SOX8 antibody

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Purity/Purification

Affinity Purification

Concentration

1mg/ml (lot specific)

Preparation and Storage

Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

446

OMIM

605923

3D Structure

ModBase 3D Structure for P57073

Species

Human

Route

Synthetic Peptide

Immunogen

A synthetic peptide of human SOX8

Calculated Molecular Weight

47kDa

Product Categories/Family for anti-SOX8 antibody

Polyclonal

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-SOX8 antibody

Western Blot (WB)

Application Notes for anti-SOX8 antibody

WB: 1:500 - 1:2000

Other Notes

Small volumes of anti-SOX8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SOX8 purchase

MBS126880 is an antibody targeting SOX8. Also known as SOX8 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SOX8. It may not necessarily be applicable to this product.

NCBI GI #

10720294

NCBI GeneID

30812

NCBI Accession #

P57073.1

UniProt Primary Accession #

P57073

UniProt Secondary Accession #

Q9NZW2

UniProt Related Accession #

P57073

NCBI Official Full Name

Transcription factor SOX-8

NCBI Official Synonym Full Names

SRY (sex determining region Y)-box 8

NCBI Official Symbol

SOX8

UniProt Protein Name

Transcription factor SOX-8

Protein Family

Transcription factor

UniProt Gene Name

SOX8

UniProt Entry Name

SOX8_HUMAN

NCBI Protein Information

transcription factor SOX-8

UniProt Comments for SOX8

SOX8: May play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3'.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: cytoplasm; nucleus

Molecular Function: DNA binding; protein heterodimerization activity; transcription factor binding

Biological Process: negative regulation of photoreceptor cell differentiation; transcription from RNA polymerase II promoter; fat cell differentiation; cell fate commitment; positive regulation of gliogenesis; in utero embryonic development; astrocyte fate commitment; positive regulation of transcription, DNA-dependent; male gonad development; cell maturation; signal transduction; Sertoli cell development; enteric nervous system development; peripheral nervous system development; osteoblast differentiation; retina development in camera-type eye; positive regulation of osteoblast proliferation; oligodendrocyte differentiation; spermatogenesis; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of myoblast differentiation; neural crest cell migration; negative regulation of apoptosis

Research Articles on SOX8

1. SOX8 mRNA levels decrease during in vitro dedifferentiation of human articular chondrocytes and increase during chondrogenic differentiation of mesenchymal stromal cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SOX8 antibody

Reference Product	PubMed Publications
JUN antibody	>12 publications with SOX8 and JUN
NR5A1 antibody	>2 publications with SOX8 and NR5A1
PAX3 antibody	>2 publications with SOX8 and PAX3
EGR2 antibody	>1 publications with SOX8 and EGR2
OLIG2 antibody	>1 publications with SOX8 and OLIG2

Diseases associated with anti-SOX8 antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>10 publications with SOX8 and Nervous System Diseases
Congenital Abnormalities Antibodies	>5 publications with SOX8 and Congenital Abnormalities
Abnormalities, Multiple Antibodies	>4 publications with SOX8 and Abnormalities, Multiple
Brain Diseases Antibodies	>3 publications with SOX8 and Brain Diseases
Peripheral Nervous System Diseases Antibodies	>3 publications with SOX8 and Peripheral Nervous System Diseases
Disease Models, Animal Antibodies	>2 publications with SOX8 and Disease Models, Animal
Carcinoma, Hepatocellular Antibodies	>1 publications with SOX8 and Carcinoma, Hepatocellular
Neural Tube Defects Antibodies	>1 publications with SOX8 and Neural Tube Defects
Nerve Degeneration Antibodies	>1 publications with SOX8 and Nerve Degeneration
Multiple Myeloma Antibodies	>1 publications with SOX8 and Multiple Myeloma

Organs/Tissues associated with anti-SOX8 antibody

Organ/Tissue Name	Pubmed Publications
Testis Antibodies	>27 publications with SOX8 and Testis
Embryonic Tissue Antibodies	>17 publications with SOX8 and Embryonic Tissue
Brain Antibodies	>13 publications with SOX8 and Brain
Nerve Antibodies	>8 publications with SOX8 and Nerve
Heart Antibodies	>6 publications with SOX8 and Heart
Eye Antibodies	>6 publications with SOX8 and Eye
Ganglia Antibodies	>5 publications with SOX8 and Ganglia
Intestine Antibodies	>1 publications with SOX8 and Intestine