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FIGF Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS126901
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The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
FIGF, Polyclonal Antibody
Full Product Name
FIGF Polyclonal Antibody
Product Gene Name
anti-FIGF antibody
Product Synonym Names
VEGFD; VEGF-D; FIGF
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
354
OMIM
300091
3D Structure
ModBase 3D Structure for O43915
Species
Human
Immunogen
Recombinant protein of human FIGF
Calculated Molecular Weight
40kDa

Product Categories/Family for anti-FIGF antibody

Polyclonal
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-FIGF antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-FIGF antibody
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200

Western Blot (WB) of anti-FIGF antibody

Western blot analysis of extracts of H640 cells, using VEGFD antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Rabbit Anti-FIGF Polyclonal Antibody – Cat# MBS126901

Immunohistochemistry (IHC) of anti-FIGF antibody

Immunohistochemistry of paraffin-embedded human lung cancer using VEGFD antibody at dilution of 1:200 (40x lens).
Rabbit Anti-FIGF Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS126901

Other Notes

Small volumes of anti-FIGF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FIGF purchase

MBS126901 is an antibody targeting FIGF. Also known as FIGF Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FIGF. It may not necessarily be applicable to this product.

NCBI GI #
17367984
NCBI GeneID
2277
NCBI Accession #
O43915.1
UniProt Primary Accession #
O43915
UniProt Secondary Accession #
B2R7Z3
UniProt Related Accession #
O43915
NCBI Official Full Name
Vascular endothelial growth factor D
NCBI Official Synonym Full Names
c-fos induced growth factor (vascular endothelial growth factor D)
NCBI Official Symbol
FIGF
NCBI Official Synonym Symbols
VEGFD; VEGF-D
UniProt Protein Name
Vascular endothelial growth factor D
UniProt Synonym Protein Names
c-Fos-induced growth factor; FIGF
Protein Family
Vascular endothelial growth factor
UniProt Gene Name
FIGF
UniProt Synonym Gene Names
VEGFD; VEGF-D; FIGF
UniProt Entry Name
VEGFD_HUMAN
NCBI Protein Information
vascular endothelial growth factor D

UniProt Comments for FIGF

VEGFD: Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. Belongs to the PDGF/VEGF growth factor family.

Protein type: Motility/polarity/chemotaxis; Secreted, signal peptide; Secreted; Cytokine

Chromosomal Location of Human Ortholog: Xp22.31

Cellular Component: extracellular space; membrane; extracellular region

Molecular Function: protein homodimerization activity; growth factor activity; platelet-derived growth factor receptor binding; vascular endothelial growth factor receptor 3 binding; vascular endothelial growth factor receptor binding; chemoattractant activity

Biological Process: platelet activation; cell proliferation; platelet degranulation; positive chemotaxis; positive regulation of cell division; positive regulation of cell proliferation; angiogenesis; vascular endothelial growth factor receptor signaling pathway; blood coagulation; cell differentiation; induction of positive chemotaxis
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Research Articles on FIGF

1. Increase of VEGFD protein expression is associated with oral squamous cell carcinoma.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FIGF antibody

 Reference Product  PubMed Publications
 FLT4 antibody  >6 publications with FIGF and FLT4
 KDR antibody  >5 publications with FIGF and KDR
 FLT1 antibody  >4 publications with FIGF and FLT1
 ALB antibody  >1 publications with FIGF and ALB

Pathways associated with anti-FIGF antibody

 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 Pathways In Cancer antibodies  Pathways In Cancer Diagram
 Platelet Activation, Signaling And Aggregation Pathway antibodies  Platelet Activation, Signaling And Aggregation Pathway Diagram

Diseases associated with anti-FIGF antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >3 publications with FIGF and Nervous System Diseases
 Breast Neoplasms Antibodies  >3 publications with FIGF and Breast Neoplasms
 Inflammation Antibodies  >3 publications with FIGF and Inflammation
 Mammary Neoplasms, Animal Antibodies  >2 publications with FIGF and Mammary Neoplasms, Animal
 Lung Neoplasms Antibodies  >2 publications with FIGF and Lung Neoplasms
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with FIGF and Prenatal Exposure Delayed Effects
 Insulin Resistance Antibodies  >1 publications with FIGF and Insulin Resistance
 Weight Gain Antibodies  >1 publications with FIGF and Weight Gain
 Kidney Diseases Antibodies  >1 publications with FIGF and Kidney Diseases
 Hyperglycemia Antibodies  >1 publications with FIGF and Hyperglycemia

Organs/Tissues associated with anti-FIGF antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >7 publications with FIGF and Lung
 Muscle Antibodies  >4 publications with FIGF and Muscle
 Kidney Antibodies  >4 publications with FIGF and Kidney
 Heart Antibodies  >3 publications with FIGF and Heart
 Spleen Antibodies  >3 publications with FIGF and Spleen
 Mammary Gland Antibodies  >2 publications with FIGF and Mammary Gland
 Intestine Antibodies  >2 publications with FIGF and Intestine
 Liver Antibodies  >2 publications with FIGF and Liver
 Uterus Antibodies  >1 publications with FIGF and Uterus
 Adrenal Gland Antibodies  >1 publications with FIGF and Adrenal Gland
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