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PGF Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS127199
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This gene encodes a growth factor found in placenta which is homologous to vascular endothelial growth factor. Alternatively spliced transcripts encoding different isoforms have been found for this gene. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PGF, Polyclonal Antibody
Full Product Name
PGF Polyclonal Antibody
Product Gene Name
anti-PGF antibody
Product Synonym Names
PGFL; PLGF; PlGF-2; D12S1900; SHGC-10760
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
221
OMIM
601121
3D Structure
ModBase 3D Structure for P49763
Species
Human
Immunogen
Recombinant protein of human PGF
Calculated Molecular Weight
24kDa

Product Categories/Family for anti-PGF antibody

Polyclonal
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PGF antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-PGF antibody
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200

Western Blot (WB) of anti-PGF antibody

Western blot analysis of extracts of various cell lines, using PGF antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Rabbit Anti-PGF Polyclonal Antibody – Cat# MBS127199

Immunohistochemistry (IHC) of anti-PGF antibody

Immunohistochemistry of paraffin-embedded human colon using PGF Antibody at dilution of 1:100 (40x lens).
Rabbit Anti-PGF Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS127199

Other Notes

Small volumes of anti-PGF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PGF purchase

MBS127199 is an antibody targeting PGF. Also known as PGF Polyclonal Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PGF. It may not necessarily be applicable to this product.

NCBI GI #
17380553
NCBI GeneID
5228
NCBI Accession #
P49763.2
UniProt Primary Accession #
P49763
UniProt Secondary Accession #
Q07101; Q9BV78; Q9Y6S8
UniProt Related Accession #
P49763
NCBI Official Full Name
Placenta growth factor
NCBI Official Synonym Full Names
placental growth factor
NCBI Official Symbol
PGF
NCBI Official Synonym Symbols
PGFL; PLGF; PlGF-2; D12S1900; SHGC-10760
UniProt Protein Name
Placenta growth factor
Protein Family
Placenta growth factor
UniProt Gene Name
PGF
UniProt Synonym Gene Names
PGFL; PLGF; PlGF
UniProt Entry Name
PLGF_HUMAN
NCBI Protein Information
placenta growth factor; placental growth factor, vascular endothelial growth factor-related protein

UniProt Comments for PGF

PGF: Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth. Belongs to the PDGF/VEGF growth factor family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 14q24.3

Cellular Component: extracellular space; membrane; extracellular region

Molecular Function: heparin binding; protein binding; protein homodimerization activity; growth factor activity; protein heterodimerization activity

Biological Process: response to drug; organ regeneration; female pregnancy; signal transduction; cellular response to hormone stimulus; positive regulation of angiogenesis; cell-cell signaling; ureteric bud branching; positive regulation of cell division; positive regulation of cell proliferation; response to hypoxia; positive regulation of endothelial cell proliferation; sprouting angiogenesis; cell differentiation; vascular endothelial growth factor receptor signaling pathway
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Research Articles on PGF

1. Data suggest that placental growth factor (PLGF) may function upstream of matrix metalloproteinase 3 (MMP3) in larynx carcinoma cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PGF antibody

 Reference Product  PubMed Publications
 VEGFA antibody  >24 publications with PGF and VEGFA
 FLT1 antibody  >20 publications with PGF and FLT1
 KDR antibody  >13 publications with PGF and KDR
 EDN1 antibody  >5 publications with PGF and EDN1
 NRP1 antibody  >4 publications with PGF and NRP1
 FLT4 antibody  >3 publications with PGF and FLT4
 AKT1 antibody  >2 publications with PGF and AKT1
 PIK3CA antibody  >1 publications with PGF and PIK3CA

Pathways associated with anti-PGF antibody

 Products by Pathway  Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 Pathways In Cancer antibodies  Pathways In Cancer Diagram
 Rap1 Signaling Pathway antibodies  Rap1 Signaling Pathway Diagram
 Rap1 Signaling Pathway antibodies  Rap1 Signaling Pathway Diagram
 Ras Signaling Pathway antibodies  Ras Signaling Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram

Diseases associated with anti-PGF antibody

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >384 publications with PGF and Cardiovascular Diseases
 Inflammation Antibodies  >285 publications with PGF and Inflammation
 Disease Models, Animal Antibodies  >159 publications with PGF and Disease Models, Animal
 Necrosis Antibodies  >154 publications with PGF and Necrosis
 Lung Diseases Antibodies  >128 publications with PGF and Lung Diseases
 Heart Diseases Antibodies  >127 publications with PGF and Heart Diseases
 Atherosclerosis Antibodies  >93 publications with PGF and Atherosclerosis
 Brain Diseases Antibodies  >72 publications with PGF and Brain Diseases
 Kidney Diseases Antibodies  >70 publications with PGF and Kidney Diseases
 Liver Diseases Antibodies  >39 publications with PGF and Liver Diseases

Organs/Tissues associated with anti-PGF antibody

 Organ/Tissue Name  Pubmed Publications
 Ovary Antibodies  >769 publications with PGF and Ovary
 Uterus Antibodies  >732 publications with PGF and Uterus
 Muscle Antibodies  >507 publications with PGF and Muscle
 Heart Antibodies  >251 publications with PGF and Heart
 Lung Antibodies  >238 publications with PGF and Lung
 Kidney Antibodies  >213 publications with PGF and Kidney
 Placenta Antibodies  >212 publications with PGF and Placenta
 Embryonic Tissue Antibodies  >198 publications with PGF and Embryonic Tissue
 Brain Antibodies  >195 publications with PGF and Brain
 Liver Antibodies  >135 publications with PGF and Liver
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