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GGA2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS127223
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This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins… More details

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Product Overview

Online Datasheet in PDF
Product Name
GGA2, Polyclonal Antibody
Full Product Name
GGA2 Polyclonal Antibody
Product Gene Name
anti-GGA2 antibody
Product Synonym Names
GGA2; FLJ20966; KIAA1080; VEAR
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
613
OMIM
606005
3D Structure
ModBase 3D Structure for Q9UJY4
Species
Human
Immunogen
Recombinant protein of human GGA2
Calculated Molecular Weight
67kDa

Product Categories/Family for anti-GGA2 antibody

Polyclonal
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-GGA2 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-GGA2 antibody
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200

Western Blot (WB) of anti-GGA2 antibody

Western blot analysis of extracts of various cell lines, using GGA2 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Rabbit Anti-GGA2 Polyclonal Antibody – Cat# MBS127223

Immunohistochemistry (IHC) of anti-GGA2 antibody

Immunohistochemistry of paraffin-embedded human kidney using GGA2 Antibody at dilution of 1:200 (40x lens).
Rabbit Anti-GGA2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS127223

Immunohistochemistry (IHC) of anti-GGA2 antibody

Immunohistochemistry of paraffin-embedded human esophageal cancer using GGA2 Antibody at dilution of 1:200 (40x lens).
Rabbit Anti-GGA2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS127223

Immunohistochemistry (IHC) of anti-GGA2 antibody

Immunohistochemistry of paraffin-embedded human stomach using GGA2 Antibody at dilution of 1:200 (40x lens).
Rabbit Anti-GGA2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS127223

Immunohistochemistry (IHC) of anti-GGA2 antibody

Immunohistochemistry of paraffin-embedded rat brain using GGA2 Antibody at dilution of 1:200 (40x lens).
Rabbit Anti-GGA2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS127223

Immunohistochemistry (IHC) of anti-GGA2 antibody

Immunohistochemistry of paraffin-embedded human gastric cancer using GGA2 Antibody at dilution of 1:200 (40x lens).
Rabbit Anti-GGA2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS127223

Immunofluorescence (IF) of anti-GGA2 antibody

Immunofluorescence analysis of MCF-7 cells using GGA2 antibody. Blue: DAPI for nuclear staining.
Rabbit Anti-GGA2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS127223

Other Notes

Small volumes of anti-GGA2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GGA2 purchase

MBS127223 is an antibody targeting GGA2. Also known as GGA2 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GGA2. It may not necessarily be applicable to this product.

NCBI GI #
143811397
NCBI GeneID
23062
NCBI Accession #
Q9UJY4.3
UniProt Primary Accession #
Q9UJY4
UniProt Secondary Accession #
O14564; Q9NYN2; Q9UPS2; D3DWF0
UniProt Related Accession #
Q9UJY4
NCBI Official Full Name
ADP-ribosylation factor-binding protein GGA2
NCBI Official Synonym Full Names
golgi-associated, gamma adaptin ear containing, ARF binding protein 2
NCBI Official Symbol
GGA2
NCBI Official Synonym Symbols
VEAR
UniProt Protein Name
ADP-ribosylation factor-binding protein GGA2
UniProt Synonym Protein Names
Gamma-adaptin-related protein 2; Golgi-localized, gamma ear-containing, ARF-binding protein 2; VHS domain and ear domain of gamma-adaptin; Vear
Protein Family
ADP-ribosylation factor-binding protein
UniProt Gene Name
GGA2
UniProt Synonym Gene Names
KIAA1080; Vear
UniProt Entry Name
GGA2_HUMAN
NCBI Protein Information
ADP-ribosylation factor-binding protein GGA2; gamma-adaptin-related protein 2; VHS domain and ear domain of gamma-adaptin; VHS domain and ear domain-containing protein; golgi-localized, gamma ear-containing, ARF-binding protein 2; golgi associated, gamma adaptin ear containing, ARF binding protein 2

UniProt Comments for GGA2

GGA2: Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif. Belongs to the GGA protein family.

Protein type: Adaptor/scaffold; Vesicle

Chromosomal Location of Human Ortholog: 16p12

Cellular Component: Golgi apparatus; clathrin adaptor complex; clathrin-coated vesicle; endosome membrane; trans-Golgi network

Molecular Function: ADP-ribosylation factor binding; protein binding

Biological Process: vesicle-mediated transport; intracellular protein transport
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Research Articles on GGA2

1. These data indicate that clathrin is required for the function of AP-1- and GGA-coated carriers at the trans-Golgi network but may be dispensable for outward traffic en route to the plasma membrane.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GGA2 antibody

 Reference Product  PubMed Publications
 M6PR antibody  >5 publications with GGA2 and M6PR
 IGF2R antibody  >5 publications with GGA2 and IGF2R
 BACE1 antibody  >3 publications with GGA2 and BACE1
 SYNRG antibody  >1 publications with GGA2 and SYNRG
 RABEP1 antibody  >1 publications with GGA2 and RABEP1

Pathways associated with anti-GGA2 antibody

 Products by Pathway  Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram

Diseases associated with anti-GGA2 antibody

 Disease Name  Pubmed Publications
 Weight Loss Antibodies  >2 publications with GGA2 and Weight Loss
 Leukemia, Myeloid, Acute Antibodies  >1 publications with GGA2 and Leukemia, Myeloid, Acute
 Mental Disorders Antibodies  >1 publications with GGA2 and Mental Disorders
 Hypertension Antibodies  >1 publications with GGA2 and Hypertension
 Kidney Diseases Antibodies  >1 publications with GGA2 and Kidney Diseases

Organs/Tissues associated with anti-GGA2 antibody

 Organ/Tissue Name  Pubmed Publications
 Ear Antibodies  >24 publications with GGA2 and Ear
 Muscle Antibodies  >9 publications with GGA2 and Muscle
 Blood Antibodies  >4 publications with GGA2 and Blood
 Kidney Antibodies  >4 publications with GGA2 and Kidney
 Brain Antibodies  >4 publications with GGA2 and Brain
 Nerve Antibodies  >3 publications with GGA2 and Nerve
 Liver Antibodies  >3 publications with GGA2 and Liver
 Bone Antibodies  >2 publications with GGA2 and Bone
 Thyroid Antibodies  >1 publications with GGA2 and Thyroid
 Spleen Antibodies  >1 publications with GGA2 and Spleen
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