Rabbit Anti-CDH13 Polyclonal Antibody – Cat# MBS127250

Western blot analysis of extracts of various cell lines, using CDH13 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.

CDH13 Antibody – Rabbit Polyclonal

Name: CDH13 Antibody; Polyclonal; Rabbit; Human/Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS127250
Price: 225 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS127250

This gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. The protein lacks the cytoplasmic domain characteristic of… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CDH13, Polyclonal Antibody

Full Product Name

CDH13 Polyclonal Antibody

Product Gene Name

anti-CDH13 antibody

Product Synonym Names

CDHH; P105

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse

Purity/Purification

Affinity Purification

Concentration

1mg/ml (lot specific)

Preparation and Storage

Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

713

OMIM

601364

3D Structure

ModBase 3D Structure for P55290

Species

Human

Immunogen

Recombinant protein of human CDH13

Calculated Molecular Weight

78kDa

Product Categories/Family for anti-CDH13 antibody

Polyclonal

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-CDH13 antibody

Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-CDH13 antibody

WB: 1:500 - 1:2000
IHC: 1:50 - 1:200

Other Notes

Small volumes of anti-CDH13 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CDH13 purchase

MBS127250 is an antibody targeting CDH13. Also known as CDH13 Polyclonal Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CDH13. It may not necessarily be applicable to this product.

NCBI GI #

1705552

NCBI GeneID

1012

NCBI Accession #

P55290.1

UniProt Primary Accession #

P55290

UniProt Secondary Accession #

Q6GTW4; Q8TBX3; A8W476; A8W477; B7Z590; C9JRI6; J3KN62

UniProt Related Accession #

P55290

NCBI Official Full Name

Cadherin-13

NCBI Official Synonym Full Names

cadherin 13

NCBI Official Symbol

CDH13

NCBI Official Synonym Symbols

CDHH; P105

UniProt Protein Name

Cadherin-13

UniProt Synonym Protein Names

Heart cadherin; H-cadherin; P105; Truncated cadherin; T-cad; T-cadherin

Protein Family

Cadherin

UniProt Gene Name

CDH13

UniProt Synonym Gene Names

CDHH; H-cadherin; T-cad; T-cadherin

UniProt Entry Name

CAD13_HUMAN

NCBI Protein Information

cadherin-13; T-cad; T-cadherin; heart cadherin; H-cadherin (heart); cadherin 13, H-cadherin (heart)

UniProt Comments for CDH13

CDH13: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, GPI anchor; Cell adhesion

Chromosomal Location of Human Ortholog: 16q23.3

Cellular Component: extracellular space; neuron projection; focal adhesion; cytoplasm; plasma membrane; caveola; external side of plasma membrane

Molecular Function: adiponectin binding; protein homodimerization activity; cadherin binding; low-density lipoprotein binding; calcium ion binding

Biological Process: lamellipodium biogenesis; intercellular junction assembly and maintenance; positive regulation of positive chemotaxis; positive regulation of smooth muscle cell proliferation; Rac protein signal transduction; positive regulation of calcium-mediated signaling; negative regulation of cell adhesion; keratinocyte proliferation; Rho protein signal transduction; regulation of epidermal growth factor receptor signaling pathway; low density lipoprotein mediated signaling; negative regulation of cell proliferation; localization within membrane; calcium-dependent cell-cell adhesion; regulation of endocytosis; endothelial cell migration; positive regulation of transcription from RNA polymerase II promoter; positive regulation of endothelial cell proliferation; sprouting angiogenesis; positive regulation of cell-matrix adhesion; homophilic cell adhesion; positive regulation of cell migration

Research Articles on CDH13

1. Adiponectin/T-cadherin and apelin/APJ expression patterns were found to be inversely associated with human aortic and coronary atherosclerosis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CDH13 antibody

Reference Product	PubMed Publications
CDH15 antibody	>3 publications with CDH13 and CDH15
CDH5 antibody	>3 publications with CDH13 and CDH5
CDH11 antibody	>3 publications with CDH13 and CDH11
CDH8 antibody	>2 publications with CDH13 and CDH8
CDH12 antibody	>1 publications with CDH13 and CDH12
CDH6 antibody	>1 publications with CDH13 and CDH6
CDH2 antibody	>1 publications with CDH13 and CDH2

Pathways associated with anti-CDH13 antibody

Products by Pathway	Pathway Diagram
Adherens Junctions Interactions Pathway antibodies	Adherens Junctions Interactions Pathway Diagram
Cell Junction Organization Pathway antibodies	Cell Junction Organization Pathway Diagram
Cell-Cell Communication Pathway antibodies	Cell-Cell Communication Pathway Diagram
Cell-cell Junction Organization Pathway antibodies	Cell-cell Junction Organization Pathway Diagram

Diseases associated with anti-CDH13 antibody

Disease Name	Pubmed Publications
Lung Neoplasms Antibodies	>35 publications with CDH13 and Lung Neoplasms
Lung Diseases Antibodies	>32 publications with CDH13 and Lung Diseases
Breast Neoplasms Antibodies	>25 publications with CDH13 and Breast Neoplasms
Carcinoma, Squamous Cell Antibodies	>24 publications with CDH13 and Carcinoma, Squamous Cell
Carcinoma, Non-Small-Cell Lung Antibodies	>20 publications with CDH13 and Carcinoma, Non-Small-Cell Lung
Neoplasms, Experimental Antibodies	>13 publications with CDH13 and Neoplasms, Experimental
Cardiovascular Diseases Antibodies	>10 publications with CDH13 and Cardiovascular Diseases
Nervous System Diseases Antibodies	>9 publications with CDH13 and Nervous System Diseases
Adenoma Antibodies	>8 publications with CDH13 and Adenoma
Precancerous Conditions Antibodies	>7 publications with CDH13 and Precancerous Conditions

Organs/Tissues associated with anti-CDH13 antibody

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>49 publications with CDH13 and Lung
Brain Antibodies	>20 publications with CDH13 and Brain
Vascular Antibodies	>11 publications with CDH13 and Vascular
Liver Antibodies	>10 publications with CDH13 and Liver
Muscle Antibodies	>10 publications with CDH13 and Muscle
Prostate Antibodies	>9 publications with CDH13 and Prostate
Skin Antibodies	>6 publications with CDH13 and Skin
Bone Antibodies	>6 publications with CDH13 and Bone
Kidney Antibodies	>5 publications with CDH13 and Kidney
Eye Antibodies	>5 publications with CDH13 and Eye