Rabbit Anti-SEPT2 Polyclonal Antibody – Cat# MBS127256

Western blot analysis of extracts of various cell lines, using SEPT2 antibody.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.

SEPT2 Antibody – Rabbit Polyclonal

Name: SEPT2 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS127256
Price: 360 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS127256

SEPT2, also named as DIFF6, KIAA0158, NEDD5 and Septin-2, belongs to the septin family. It is a filament-forming cytoskeletal GTPase. SEPT2 is required for normal organization of the actin cytoskeleton. It plays a role in ciliogenesis and collective cell… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

SEPT2, Polyclonal Antibody

Full Product Name

SEPT2 Polyclonal Antibody

Product Gene Name

anti-SEPT2 antibody

Product Synonym Names

DIFF6; NEDD5; Pnutl3; hNedd5

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Purity/Purification

Affinity Purification

Concentration

1mg/ml (lot specific)

Preparation and Storage

Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

361

OMIM

601506

3D Structure

ModBase 3D Structure for Q15019

Species

Human

Immunogen

Recombinant protein of human SEPT2

Calculated Molecular Weight

41kDa

Product Categories/Family for anti-SEPT2 antibody

Polyclonal

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-SEPT2 antibody

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)

Application Notes for anti-SEPT2 antibody

WB: 1:500 - 1:1000
IHC: 1:50 - 1:100
IF: 1:20 - 1:50
IP: 1:20 - 1:50
FC: 1:20 - 1:50

Other Notes

Small volumes of anti-SEPT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SEPT2 purchase

MBS127256 is an antibody targeting SEPT2. Also known as SEPT2 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SEPT2. It may not necessarily be applicable to this product.

NCBI GI #

2500769

NCBI GeneID

4735

NCBI Accession #

Q15019.1

UniProt Primary Accession #

Q15019

UniProt Secondary Accession #

Q14132; Q53QU3; Q8IUK9; Q96CB0; B4DGE8

UniProt Related Accession #

Q15019

NCBI Official Full Name

Septin-2

NCBI Official Synonym Full Names

septin 2

NCBI Official Symbol

SEPT2

NCBI Official Synonym Symbols

DIFF6; NEDD5; NEDD-5; Pnutl3; hNedd5

UniProt Protein Name

Septin-2

UniProt Synonym Protein Names

Neural precursor cell expressed developmentally down-regulated protein 5; NEDD-5

UniProt Gene Name

SEPT2

UniProt Synonym Gene Names

DIFF6; KIAA0158; NEDD5; NEDD-5

UniProt Entry Name

SEPT2_HUMAN

NCBI Protein Information

septin-2; neural precursor cell expressed, developmentally down-regulated 5; neural precursor cell expressed developmentally down-regulated protein 5

UniProt Comments for SEPT2

SEPT2: a member of the septin family of proteins. May be involved in the process of cytokinesis. Accumulates near the contractile ring from anaphase through telophase, and finally condenses into the midbody. In interphase and postmitotic cells, localized to fibrous or granular structures, depending on the growth state of the cell.

Protein type: Cytoskeletal; Hydrolase; Cell development/differentiation; Motility/polarity/chemotaxis; Cell cycle regulation

Chromosomal Location of Human Ortholog: 2q37

Cellular Component: nucleoplasm; perinuclear region of cytoplasm; cytoplasm; nucleolus; exocyst; synapse; spindle; midbody; cell cortex; nucleus; actin cytoskeleton; cleavage furrow

Molecular Function: protein binding; GTP binding; protein complex scaffold; enzyme regulator activity

Biological Process: mitosis; smoothened signaling pathway; regulation of protein localization; regulation of catalytic activity; cell division; cilium biogenesis; regulation of L-glutamate transport; neurite development

Research Articles on SEPT2

1. SEPT2 forms a 1:1:1 complex with SEPT7 and SEPT9.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SEPT2 antibody

Reference Product	PubMed Publications
SEPT7 antibody	>28 publications with SEPT2 and SEPT7
SEPT6 antibody	>22 publications with SEPT2 and SEPT6
SEPT9 antibody	>17 publications with SEPT2 and SEPT9
SEPT5 antibody	>8 publications with SEPT2 and SEPT5
SEPT14 antibody	>2 publications with SEPT2 and SEPT14
S100A4 antibody	>1 publications with SEPT2 and S100A4

Pathways associated with anti-SEPT2 antibody

Products by Pathway	Pathway Diagram
Anchoring Of The Basal Body To The Plasma Membrane Pathway antibodies	Anchoring Of The Basal Body To The Plasma Membrane Pathway Diagram
Assembly Of The Primary Cilium Pathway antibodies	Assembly Of The Primary Cilium Pathway Diagram
Bacterial Invasion Of Epithelial Cells Pathway antibodies	Bacterial Invasion Of Epithelial Cells Pathway Diagram
Bacterial Invasion Of Epithelial Cells Pathway antibodies	Bacterial Invasion Of Epithelial Cells Pathway Diagram
CDC42 Signaling Events Pathway antibodies	CDC42 Signaling Events Pathway Diagram
Organelle Biogenesis And Maintenance Pathway antibodies	Organelle Biogenesis And Maintenance Pathway Diagram

Diseases associated with anti-SEPT2 antibody

Disease Name	Pubmed Publications
Atrophy Antibodies	>2 publications with SEPT2 and Atrophy
Nephritis Antibodies	>1 publications with SEPT2 and Nephritis
Hemorrhage Antibodies	>1 publications with SEPT2 and Hemorrhage
Hypertension Antibodies	>1 publications with SEPT2 and Hypertension
Infertility, Male Antibodies	>1 publications with SEPT2 and Infertility, Male
Edema Antibodies	>1 publications with SEPT2 and Edema
Inflammation Antibodies	>1 publications with SEPT2 and Inflammation
Kidney Diseases Antibodies	>1 publications with SEPT2 and Kidney Diseases

Organs/Tissues associated with anti-SEPT2 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>11 publications with SEPT2 and Brain
Nerve Antibodies	>8 publications with SEPT2 and Nerve
Blood Antibodies	>7 publications with SEPT2 and Blood
Eye Antibodies	>4 publications with SEPT2 and Eye
Kidney Antibodies	>2 publications with SEPT2 and Kidney
Skin Antibodies	>2 publications with SEPT2 and Skin
Muscle Antibodies	>2 publications with SEPT2 and Muscle
Heart Antibodies	>2 publications with SEPT2 and Heart
Testis Antibodies	>2 publications with SEPT2 and Testis
Liver Antibodies	>1 publications with SEPT2 and Liver