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GABRR1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS127338
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MBS127338 is an antibody targeting GABRR1. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
GABRR1, Polyclonal Antibody
Full Product Name
GABRR1
Product Gene Name
anti-GABRR1 antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Molecular Weight
479
OMIM
137161
3D Structure
ModBase 3D Structure for P24046
Species
Human
Route
Synthetic Peptide

Product Categories/Family for anti-GABRR1 antibody

Polyclonal
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-GABRR1 antibody
Western Blot (WB), Immunohistochemistry (IHC)

Western Blot (WB) of anti-GABRR1 antibody

Western blot analysis of extracts of various cell lines, using GABRR1 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.
Rabbit Anti-GABRR1 Polyclonal Antibody – Cat# MBS127338

Other Notes

Small volumes of anti-GABRR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GABRR1. It may not necessarily be applicable to this product.

NCBI GI #
223590210
NCBI GeneID
2569
NCBI Accession #
P24046.2
UniProt Primary Accession #
P24046
UniProt Secondary Accession #
Q9BX06; A1L401; B4DJK8; B4DQT5; B7ZBQ7
UniProt Related Accession #
P24046
NCBI Official Full Name
Gamma-aminobutyric acid receptor subunit rho-1
NCBI Official Synonym Full Names
gamma-aminobutyric acid (GABA) A receptor, rho 1
NCBI Official Symbol
GABRR1
UniProt Protein Name
Gamma-aminobutyric acid receptor subunit rho-1
UniProt Synonym Protein Names
GABA(A) receptor subunit rho-1; GABA(C) receptor
Protein Family
Gamma-aminobutyric acid receptor
UniProt Gene Name
GABRR1
UniProt Entry Name
GBRR1_HUMAN
NCBI Protein Information
gamma-aminobutyric acid receptor subunit rho-1; GABA(C) receptor; GABA(A) receptor, rho 1; GABA(A) receptor subunit rho-1; gamma-aminobutyric acid (GABA) receptor, rho 1; gamma-aminobutyric acid (GABA) A receptor, rho-1; bA135P14.1 (gamma-aminobutyric acid (GABA) receptor, rho 1)

NCBI Summary for GABRR1

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR1 is a member of the rho subunit family. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
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UniProt Comments for GABRR1

GABRR1: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRR1 sub-subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, misc.; Transporter; Transporter, ion channel; Channel, ligand-gated; Membrane protein, multi-pass; Channel, chloride; Membrane protein, integral

Chromosomal Location of Human Ortholog: 6q15

Cellular Component: postsynaptic membrane; integral to plasma membrane; plasma membrane; cell junction

Molecular Function: chloride channel activity; GABA-A receptor activity; extracellular ligand-gated ion channel activity

Biological Process: synaptic transmission; transport; transmembrane transport; gamma-aminobutyric acid signaling pathway
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Research Articles on GABRR1

1. Data indicate that all compounds from the study exhibited increased selectivity for GABAC.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GABRR1 antibody

 Reference Product  PubMed Publications
 GABRR2 antibody  >11 publications with GABRR1 and GABRR2
 GABRR3 antibody  >4 publications with GABRR1 and GABRR3
 CGA antibody  >1 publications with GABRR1 and CGA

Pathways associated with anti-GABRR1 antibody

 Products by Pathway  Pathway Diagram
 GABA A (rho) Receptor Activation Pathway antibodies  GABA A (rho) Receptor Activation Pathway Diagram
 GABA Receptor Activation Pathway antibodies  GABA Receptor Activation Pathway Diagram
 GABAergic Synapse Pathway antibodies  GABAergic Synapse Pathway Diagram
 GABAergic Synapse Pathway antibodies  GABAergic Synapse Pathway Diagram
 Ion Channel Transport Pathway antibodies  Ion Channel Transport Pathway Diagram
 Ligand-gated Ion Channel Transport Pathway antibodies  Ligand-gated Ion Channel Transport Pathway Diagram
 Morphine Addiction Pathway antibodies  Morphine Addiction Pathway Diagram
 Morphine Addiction Pathway antibodies  Morphine Addiction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram

Diseases associated with anti-GABRR1 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >2 publications with GABRR1 and Nervous System Diseases
 Disease Models, Animal Antibodies  >1 publications with GABRR1 and Disease Models, Animal
 Brain Diseases Antibodies  >1 publications with GABRR1 and Brain Diseases

Organs/Tissues associated with anti-GABRR1 antibody

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >7 publications with GABRR1 and Eye
 Brain Antibodies  >6 publications with GABRR1 and Brain
 Connective Tissue Antibodies  >1 publications with GABRR1 and Connective Tissue
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