Rabbit Anti-CYP2D6 Polyclonal Antibody – Cat# MBS127426

Western blot analysis of extracts of various cell lines, using CYP2D6 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 10s.

CYP2D6 Antibody – Rabbit Polyclonal

Name: CYP2D6 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS127426
Price: 225 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS127426

The P450II family comprises at least five subfamilies, designated A through E by the system of nomenclature recommended by an international committee. The P450IID subfamily comprises at least two genes in the rat, one of which is highly specific for… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CYP2D6, Polyclonal Antibody

Full Product Name

CYP2D6 Polyclonal Antibody

Product Gene Name

anti-CYP2D6 antibody

Product Synonym Names

CYP2D6; CYP2D6; CYP2DL1; Cytochrome P450 2D6; CYPIID6; Cytochrome P450DB1; Debrisoquine 4hydroxylase;

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Purity/Purification

Affinity purification

Preparation and Storage

Store at -20 degree C or -80 degree C. Avoid freeze / thaw cycles.

Molecular Weight

56kDa

Chromosome Location

Chromosome: 22; NC_000022.10 (42522501..42526883, complement). Location: 22q13.1

OMIM

124030

3D Structure

ModBase 3D Structure for P10635

Immunogen

A synthetic peptide of human CYP2D6

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-CYP2D6 antibody

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FC/FACS)

Application Notes for anti-CYP2D6 antibody

Western Blot (WB): 1:100-1:500
Immunohistochemistry (IHC): 1:50-1:100
Immunofluorescence (IF): 1:20-1:50
Flow Cytometry (FC/FACS): 1:20-1:50

Other Notes

Small volumes of anti-CYP2D6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CYP2D6 purchase

MBS127426 is an antibody targeting CYP2D6. Also known as CYP2D6 Polyclonal Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CYP2D6. It may not necessarily be applicable to this product.

NCBI GI #

392513721

NCBI GeneID

1565

NCBI Accession #

NP_000097.3

UniProt Primary Accession #

P10635

UniProt Secondary Accession #

Q16752; Q2XND6; Q2XND7; Q2XNE0; Q6B012; Q6NXU8

UniProt Related Accession #

P10635

GenBank Nucleotide #

NM_000106.5

NCBI Official Full Name

cytochrome P450 2D6 isoform 1

NCBI Official Synonym Full Names

cytochrome P450, family 2, subfamily D, polypeptide 6

NCBI Official Symbol

CYP2D6

NCBI Official Synonym Symbols

CPD6; CYP2D; CYP2DL1; CYPIID6; P450C2D; P450DB1; CYP2D7AP; CYP2D7BP; CYP2D7P2; CYP2D8P2; P450-DB1

UniProt Protein Name

Cytochrome P450 2D6

UniProt Synonym Protein Names

CYPIID6; Cytochrome P450-DB1; Debrisoquine 4-hydroxylase

Protein Family

Cytochrome

UniProt Gene Name

CYP2D6

UniProt Synonym Gene Names

CYP2DL1

UniProt Entry Name

CP2D6_HUMAN

NCBI Protein Information

cytochrome P450 2D6; cytochrome P450-DB1; microsomal monooxygenase; xenobiotic monooxygenase; debrisoquine 4-hydroxylase; flavoprotein-linked monooxygenase; cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 2; cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 2; cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing)-like 1; cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing), polypeptide 6; cytochrome P450, subfamily II (debrisoquine, sparteine, etc., -metabolising), polypeptide 7 pseudogene 2; cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolising), polypeptide 8 pseudogene 2

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CYP2D6 antibody

Reference Product	PubMed Publications
UGT1A1 antibody	>50 publications with CYP2D6 and UGT1A1
UGT2B7 antibody	>38 publications with CYP2D6 and UGT2B7
FMO3 antibody	>29 publications with CYP2D6 and FMO3
UGT1A4 antibody	>10 publications with CYP2D6 and UGT1A4
UGT1A6 antibody	>10 publications with CYP2D6 and UGT1A6
UGT1A9 antibody	>8 publications with CYP2D6 and UGT1A9
UGT1A3 antibody	>6 publications with CYP2D6 and UGT1A3
UGT1A8 antibody	>5 publications with CYP2D6 and UGT1A8
UGT1A10 antibody	>2 publications with CYP2D6 and UGT1A10

Pathways associated with anti-CYP2D6 antibody

Products by Pathway	Pathway Diagram
Biological Oxidations Pathway antibodies	Biological Oxidations Pathway Diagram
CYP2E1 Reactions Pathway antibodies	CYP2E1 Reactions Pathway Diagram
Codeine And Morphine Metabolism Pathway antibodies	Codeine And Morphine Metabolism Pathway Diagram
Cytochrome P450 - Arranged By Substrate Type Pathway antibodies	Cytochrome P450 - Arranged By Substrate Type Pathway Diagram
Drug Metabolism - Cytochrome P450 Pathway antibodies	Drug Metabolism - Cytochrome P450 Pathway Diagram
Drug Metabolism - Cytochrome P450 Pathway antibodies	Drug Metabolism - Cytochrome P450 Pathway Diagram
Fatty Acid Omega Oxidation Pathway antibodies	Fatty Acid Omega Oxidation Pathway Diagram
Fatty Acids Pathway antibodies	Fatty Acids Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Xenobiotics By Cytochrome P450 Pathway antibodies	Metabolism Of Xenobiotics By Cytochrome P450 Pathway Diagram

Diseases associated with anti-CYP2D6 antibody

Disease Name	Pubmed Publications
Drug Toxicity Antibodies	>363 publications with CYP2D6 and Drug Toxicity
Breast Neoplasms Antibodies	>248 publications with CYP2D6 and Breast Neoplasms
Substance-Related Disorders Antibodies	>183 publications with CYP2D6 and Substance-Related Disorders
Depressive Disorder Antibodies	>180 publications with CYP2D6 and Depressive Disorder
Movement Disorders Antibodies	>144 publications with CYP2D6 and Movement Disorders
Basal Ganglia Diseases Antibodies	>139 publications with CYP2D6 and Basal Ganglia Diseases
Parkinson Disease Antibodies	>95 publications with CYP2D6 and Parkinson Disease
Nausea Antibodies	>59 publications with CYP2D6 and Nausea
Hypertension Antibodies	>53 publications with CYP2D6 and Hypertension
Alzheimer Disease Antibodies	>48 publications with CYP2D6 and Alzheimer Disease

Organs/Tissues associated with anti-CYP2D6 antibody

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>1552 publications with CYP2D6 and Liver
Blood Antibodies	>1127 publications with CYP2D6 and Blood
Brain Antibodies	>208 publications with CYP2D6 and Brain
Intestine Antibodies	>65 publications with CYP2D6 and Intestine
Mouth Antibodies	>30 publications with CYP2D6 and Mouth
Prostate Antibodies	>18 publications with CYP2D6 and Prostate
Spleen Antibodies	>10 publications with CYP2D6 and Spleen
Uterus Antibodies	>10 publications with CYP2D6 and Uterus
Testis Antibodies	>5 publications with CYP2D6 and Testis
Mammary Gland Antibodies	>3 publications with CYP2D6 and Mammary Gland