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TRAF7 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS127778
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Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-terminal cysteine/histidine-rich region containing zinc… More details

$225 / 0.02 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TRAF7, Polyclonal Antibody
Full Product Name
TRAF7 Polyclonal Antibody
Product Gene Name
anti-TRAF7 antibody
Product Synonym Names
RFWD1; RNF119
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
670
OMIM
606692
3D Structure
ModBase 3D Structure for Q6Q0C0
Species
Human
Route
Synthetic Peptide
Immunogen
A synthetic peptide of human TRAF7
Calculated Molecular Weight
67kD

Product Categories/Family for anti-TRAF7 antibody

Polyclonal
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TRAF7 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-TRAF7 antibody
WB: 1:500 - 1:1000
IHC: 1:50 - 1:100

Western Blot (WB) of anti-TRAF7 antibody

Western blot analysis of extracts of mouse fetal stomach, using TRAF7 antibody.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Rabbit Anti-TRAF7 Polyclonal Antibody – Cat# MBS127778

Other Notes

Small volumes of anti-TRAF7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TRAF7 purchase

MBS127778 is an antibody targeting TRAF7. Also known as TRAF7 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TRAF7. It may not necessarily be applicable to this product.

NCBI GI #
54036486
NCBI GeneID
84231
NCBI Accession #
Q6Q0C0.1
UniProt Primary Accession #
Q6Q0C0
UniProt Secondary Accession #
Q9H073
UniProt Related Accession #
Q6Q0C0
NCBI Official Full Name
E3 ubiquitin-protein ligase TRAF7
NCBI Official Synonym Full Names
TNF receptor-associated factor 7, E3 ubiquitin protein ligase
NCBI Official Symbol
TRAF7
NCBI Official Synonym Symbols
RFWD1; RNF119
UniProt Protein Name
E3 ubiquitin-protein ligase TRAF7
UniProt Synonym Protein Names
RING finger and WD repeat-containing protein 1; RING finger protein 119; TNF receptor-associated factor 7
Protein Family
E3 ubiquitin-protein ligase
UniProt Gene Name
TRAF7
UniProt Synonym Gene Names
RFWD1; RNF119
UniProt Entry Name
TRAF7_HUMAN
NCBI Protein Information
E3 ubiquitin-protein ligase TRAF7; RING finger protein 119; ring finger and WD repeat domain 1; RING finger and WD repeat-containing protein 1

UniProt Comments for TRAF7

TRAF7: E3 ubiquitin ligase capable of auto-ubiquitination, following phosphorylation by MAP3K3. Potentiates MEKK3-mediated activation of the NF-kappa-B, JUN/AP1 and DDIT3 transcriptional regulators. Induces apoptosis when overexpressed. Belongs to the WD repeat TRAF7 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Ubiquitin conjugating system; EC 6.3.2.-; Ubiquitin ligase; EC 6.3.2.19; Ligase

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: intracellular membrane-bound organelle; perinuclear region of cytoplasm; cytoplasmic membrane-bound vesicle; plasma membrane; nucleus; cytosol; ubiquitin ligase complex

Molecular Function: protein binding; zinc ion binding; ubiquitin-protein ligase activity; ligase activity

Biological Process: positive regulation of protein sumoylation; regulation of protein localization; positive regulation of MAPKKK cascade; transcription, DNA-dependent; apoptosis; activation of MAPKKK activity; protein ubiquitination; negative regulation of transcription from RNA polymerase II promoter
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Research Articles on TRAF7

1. Downregulation of ubiquitin E3 ligase TNF receptor-associated factor 7 leads to stabilization of p53 in breast cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TRAF7 antibody

 Reference Product  PubMed Publications
 TRAF6 antibody  >4 publications with TRAF7 and TRAF6
 CYLD antibody  >2 publications with TRAF7 and CYLD
 MAP3K3 antibody  >1 publications with TRAF7 and MAP3K3

Diseases associated with anti-TRAF7 antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >15 publications with TRAF7 and Necrosis
 Inflammation Antibodies  >3 publications with TRAF7 and Inflammation
 Brain Edema Antibodies  >1 publications with TRAF7 and Brain Edema
 Hypertension Antibodies  >1 publications with TRAF7 and Hypertension
 Edema Antibodies  >1 publications with TRAF7 and Edema
 Seizures Antibodies  >1 publications with TRAF7 and Seizures
 Kidney Diseases Antibodies  >1 publications with TRAF7 and Kidney Diseases

Organs/Tissues associated with anti-TRAF7 antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >3 publications with TRAF7 and Muscle
 Brain Antibodies  >2 publications with TRAF7 and Brain
 Kidney Antibodies  >1 publications with TRAF7 and Kidney
 Heart Antibodies  >1 publications with TRAF7 and Heart
 Ascites Antibodies  >1 publications with TRAF7 and Ascites
 Lung Antibodies  >1 publications with TRAF7 and Lung
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