Rabbit Anti-CXCL12 Polyclonal Antibody – Cat# MBS127893

Western blot analysis of extracts of NCI-H292 cells, using CXCL12 antibody.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.

CXCL12 Antibody – Rabbit Polyclonal

Name: CXCL12 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS127893
Price: 225 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS127893

The stromal cell derived factor 1 (SDF1, CXCL12) is a small, proinflammatory chemoattractant cytokine that regulates leukocyte trafficking through interactions with its cognate 7transmembrane G proteincoupled receptors (1). The SDF1 receptor, CXCR4, also… More details

$225 / 0.02 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SDF1 (CXCL12), Polyclonal Antibody

Full Product Name

SDF1 Polyclonal Antibody

Product Gene Name

anti-CXCL12 antibody

Product Synonym Names

CXCL12; SDF1 ; CXCL12; SDF1; SDF1A; SDF1B; Stromal cellderived factor 1; CXC motif chemokine 12; Intercrine reduced in hepatomas; PreB cell growthstimulating factor; SDF1beta(372) ; SDF1alpha(367) ;

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Purity/Purification

Affinity purification

Preparation and Storage

Store at -20 degree C or -80 degree C. Avoid freeze / thaw cycles.

Molecular Weight

11kDa

Chromosome Location

Chromosome: 10; NC_000010.10 (44865601..44880545, complement). Location: 10q11.1

OMIM

600835

3D Structure

ModBase 3D Structure for P48061

Immunogen

A synthetic peptide of human SDF1

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-CXCL12 antibody

Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-CXCL12 antibody

Western Blot (WB): 1:200-1:500
Immunohistochemistry (IHC): 1:50-1:100

Product References and Citations for anti-CXCL12 antibody

1. Maekawa, T. and Ishii, T. (2000) Intern. Med. 39, 90100. 2. Ray, N. and Doms, R.W. (2006) Curr. Top. Microbiol. Immunol. 303, 97120. 3. Sugiyama, T. et al. (2006) Immunity 25, 977988 4. Ara, T. et al. (2003) Immunity 19, 257267 5. Kucia, M. et al. (2004) J. Mol. Histol. 35, 233245. 6. Ratajczak, M.Z. et al. (2006) Leukemia 20, 19151924. 7. De La Luz Sierra, M. et al. (2004) Blood 103, 24522459 8. Gleichmann, M. et al. (2000) Eur. J. Neurosci. 12, 18571866. 9. Yu, L. et al. (2006) Gene 374, 174179.

Other Notes

Small volumes of anti-CXCL12 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CXCL12 purchase

MBS127893 is an antibody targeting CXCL12. Also known as SDF1 Polyclonal Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CXCL12. It may not necessarily be applicable to this product.

NCBI GI #

10834988

NCBI GeneID

6387

NCBI Accession #

NP_000600.1

UniProt Primary Accession #

P48061

UniProt Secondary Accession #

Q2L985; Q2L986; Q2L988; Q5IT36; Q6ICW0; Q9H554; B2R4G0; E7EVL0

UniProt Related Accession #

P48061

GenBank Nucleotide #

NM_000609.6

NCBI Official Full Name

stromal cell-derived factor 1 isoform beta

NCBI Official Synonym Full Names

chemokine (C-X-C motif) ligand 12

NCBI Official Symbol

CXCL12

NCBI Official Synonym Symbols

IRH; PBSF; SDF1; TLSF; TPAR1; SCYB12

UniProt Protein Name

Stromal cell-derived factor 1

UniProt Synonym Protein Names

C-X-C motif chemokine 12; Intercrine reduced in hepatomas; IRH; hIRH; Pre-B cell growth-stimulating factor

Protein Family

Stromal cell-derived factor

UniProt Gene Name

CXCL12

UniProt Synonym Gene Names

SDF1; SDF1A; SDF1B; SDF-1; hSDF-1; IRH; hIRH; PBSF

UniProt Entry Name

SDF1_HUMAN

NCBI Protein Information

stromal cell-derived factor 1; intercrine reduced in hepatomas; pre-B cell growth-stimulating factor

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CXCL12 antibody

Reference Product	PubMed Publications
CXCR4 antibody	>2872 publications with CXCL12 and CXCR4
CCR5 antibody	>278 publications with CXCL12 and CCR5
CXCR7 antibody	>193 publications with CXCL12 and CXCR7
CXCR3 antibody	>114 publications with CXCL12 and CXCR3
HIF1A antibody	>68 publications with CXCL12 and HIF1A
CCR4 antibody	>40 publications with CXCL12 and CCR4
STAT3 antibody	>30 publications with CXCL12 and STAT3
JAK2 antibody	>16 publications with CXCL12 and JAK2
VAV1 antibody	>14 publications with CXCL12 and VAV1
SDC4 antibody	>5 publications with CXCL12 and SDC4

Pathways associated with anti-CXCL12 antibody

Products by Pathway	Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
CXCR4-mediated Signaling Events Pathway antibodies	CXCR4-mediated Signaling Events Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram

Diseases associated with anti-CXCL12 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>1293 publications with CXCL12 and Neoplasms
Cardiovascular Diseases Antibodies	>483 publications with CXCL12 and Cardiovascular Diseases
Inflammation Antibodies	>464 publications with CXCL12 and Inflammation
Neoplasm Metastasis Antibodies	>325 publications with CXCL12 and Neoplasm Metastasis
HIV Infections Antibodies	>256 publications with CXCL12 and HIV Infections
Breast Neoplasms Antibodies	>230 publications with CXCL12 and Breast Neoplasms
Heart Diseases Antibodies	>224 publications with CXCL12 and Heart Diseases
Neoplasm Invasiveness Antibodies	>186 publications with CXCL12 and Neoplasm Invasiveness
Necrosis Antibodies	>185 publications with CXCL12 and Necrosis
Myocardial Infarction Antibodies	>174 publications with CXCL12 and Myocardial Infarction

Organs/Tissues associated with anti-CXCL12 antibody

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>1270 publications with CXCL12 and Bone
Bone Marrow Antibodies	>1174 publications with CXCL12 and Bone Marrow
Vascular Antibodies	>938 publications with CXCL12 and Vascular
Brain Antibodies	>415 publications with CXCL12 and Brain
Muscle Antibodies	>312 publications with CXCL12 and Muscle
Lung Antibodies	>277 publications with CXCL12 and Lung
Heart Antibodies	>250 publications with CXCL12 and Heart
Liver Antibodies	>228 publications with CXCL12 and Liver
Embryonic Tissue Antibodies	>187 publications with CXCL12 and Embryonic Tissue
Nerve Antibodies	>151 publications with CXCL12 and Nerve