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Chordin-Like Protein 2 (CHRDL2) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1280367

MBS1280367 is a recombinant protein targeting CHRDL2. Also known as Recombinant Human Chordin-like protein 2 (CHRDL2). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1140 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Chordin-like protein 2 (CHRDL2), Recombinant Protein
Full Product Name
Recombinant Human Chordin-like protein 2 (CHRDL2)
Product Synonym Gene Name
CHRDL2
Sequence
RARPDMFCLF HGKRYSPGES WHPYLEPQGL MYCLRCTCSE GAHVSCYRLH CPPVHCPQPV TEPQQCCPKC VEPHTPSGLR APPKSCQHNG TMYQHGEIFS AHELFPSRLP NQCVLCSCTE GQIYCGLTTC PEPGCPAPLP LPDSCCQACK DEASEQSDEE DSVQSLHGVR HPQDPCSSDA GRKRGPGTPA PTGLSAPLSF IPRHFRPKGA GSTTVKIVLK EKHKKACVHG GKTYSHGEVW HPAFRAFGPL PCILCTCEDG RQDCQRVTCP TEYPCRHPEK VAGKCCKICP EDKADPGHSE ISSTRCPKAP GRVLVHTSVS PSPDNLRRFA LEHEASDLVE IYLWKLVKGI FHLTQIKKVR KQDFQKEAQH FRLLAGPHEG HWNVFLAQTL ELKVTASPDK VTKT
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
9,846 Da
Sequence Positions
26-429, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
613127
3D Structure
ModBase 3D Structure for Q6WN34
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CHRDL2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CHRDL2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
chordin-like protein 2 isoform 2
NCBI Official Synonym Full Names
chordin like 2
NCBI Official Symbol
CHRDL2
NCBI Official Synonym Symbols
BNF1; CHL2
UniProt Protein Name
Chordin-like protein 2
UniProt Synonym Protein Names
Breast tumor novel factor 1; BNF-1; Chordin-related protein 2
Protein Family
UniProt Gene Name
CHRDL2
UniProt Synonym Gene Names
BNF1; CHL2; BNF-1
NCBI Protein Information
chordin-like protein 2

NCBI Summary for CHRDL2

This gene encodes a member of the chordin family of proteins. Chordin family members are secreted proteins that share a cysteine-rich pro-collagen repeat domain and associate with members of the transforming growth factor beta superfamily. In vitro assays demonstrate a direct interaction between the encoded protein and human activin A. This gene is expressed in many tissues including osteoblasts, where it is differentially expressed during differentiation. In addition, its expression is upregulated in human osteoarthritic joint cartilage, suggesting a role in adult cartilage regeneration. [provided by RefSeq, Jan 2015]
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UniProt Comments for CHRDL2

May inhibit BMPs activity by blocking their interaction with their receptors. Has a negative regulator effect on the cartilage formation/regeneration from immature mesenchymal cells, by preventing or reducing the rate of matrix accumulation (). Implicated in tumor angiogenesis. May play a role during myoblast and osteoblast differentiation, and maturation.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CHRDL2 recombinant protein

 Reference Product  PubMed Publications
 BMP2 recombinant protein  >2 publications with CHRDL2 and BMP2

Diseases associated with CHRDL2 recombinant protein

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