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C-Type Lectin Domain Family 4 Member A (CLEC4A) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1281256

This gene encodes a member of the C-type lectinC-type lectin-like domain (CTLCTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in… More details

$825 / 0.05 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
C-type lectin domain family 4 member A (CLEC4A), Recombinant Protein
Full Product Name
Recombinant Human C-type lectin domain family 4 member A (CLEC4A), partial
Product Gene Name
CLEC4A recombinant protein
Product Synonym Gene Name
CLEC4A
Sequence
QKYSQLLEKK TTKELVHTTL ECVKKNMPVE ETAWSCCPKN WKSFSSNCYF ISTESASWQD SEKDCARMEA HLLVINTQEE QDFIFQNLQE ESAYFVGLSD PEGQRHWQWV DQTPYNESST FWHPREPSDP NERCVVLNFR KSPKRWGWND VNCLGPQRSV CEMMKIHL
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
19,280 Da
Sequence Positions
70-237. Partial, covers the complete extracellular domain.
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
605306
3D Structure
ModBase 3D Structure for Q9UMR7
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CLEC4A recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CLEC4A purchase

MBS1281256 is a recombinant protein targeting CLEC4A. Also known as Recombinant Human C-type lectin domain family 4 member A (CLEC4A), partial. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for CLEC4A. It may not necessarily be applicable to this product.

NCBI GI #
7705338
NCBI GeneID
50856
NCBI Accession #
NP_057268.1
UniProt Primary Accession #
Q9UMR7
UniProt Secondary Accession #
Q17R69; Q8WXW9; Q9H2Z9; Q9NS33; Q9UI34
UniProt Related Accession #
Q9UMR7
GenBank Nucleotide #
NM_016184.3
NCBI Official Full Name
C-type lectin domain family 4 member A isoform 1
NCBI Official Synonym Full Names
C-type lectin domain family 4 member A
NCBI Official Symbol
CLEC4A
NCBI Official Synonym Symbols
DCIR; LLIR; CD367; DDB27; CLECSF6; HDCGC13P
UniProt Protein Name
C-type lectin domain family 4 member A
UniProt Synonym Protein Names
C-type lectin DDB27; C-type lectin superfamily member 6; Dendritic cell immunoreceptor; Lectin-like immunoreceptor
Protein Family
C-type lectin domain family
UniProt Gene Name
CLEC4A
UniProt Synonym Gene Names
CLECSF6; DCIR; LLIR
NCBI Protein Information
C-type lectin domain family 4 member A

NCBI Summary for CLEC4A

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in inflammatory and immune response. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]
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UniProt Comments for CLEC4A

May be involved in regulating immune reactivity. May play a role in modulating dendritic cells (DC) differentiation and/or maturation. May be involved via its ITIM motif (immunoreceptor tyrosine-based inhibitory motifs) in the inhibition of B-cell-receptor-mediated calcium mobilization and protein tyrosine phosphorylation.
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Research Articles on CLEC4A

1. DCIR SNP rs2377422 is a novel genetic susceptibility factor for both SLE and primary SS.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CLEC4A recombinant protein

 Reference Product  PubMed Publications
 PTPN6 recombinant protein  >1 publications with CLEC4A and PTPN6

Diseases associated with CLEC4A recombinant protein

 Disease Name  Pubmed Publications
 Infection Antibodies  >9 publications with CLEC4A and Infection
 Immune System Diseases Antibodies  >8 publications with CLEC4A and Immune System Diseases
 Bronchial Hyperreactivity Antibodies  >1 publications with CLEC4A and Bronchial Hyperreactivity
 Respiratory Tract Diseases Antibodies  >1 publications with CLEC4A and Respiratory Tract Diseases

Organs/Tissues associated with CLEC4A recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >2 publications with CLEC4A and Skin
 Bone Marrow Antibodies  >2 publications with CLEC4A and Bone Marrow
 Spleen Antibodies  >1 publications with CLEC4A and Spleen
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