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TGFBI Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS128127
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This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
TGFBI, Polyclonal Antibody
Full Product Name
TGFBI Polyclonal Antibody
Product Gene Name
anti-TGFBI antibody
Product Synonym Names
CSD; CDB1; CDG2; CSD1; CSD2; CSD3; EBMD; LCD1; BIGH3; CDGG1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
683
OMIM
phenotype 608471
3D Structure
ModBase 3D Structure for Q15582
Species
Human
Immunogen
Recombinant protein of human TGFBI
Calculated Molecular Weight
75kDa

Product Categories/Family for anti-TGFBI antibody

Polyclonal
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TGFBI antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-TGFBI antibody
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200

Western Blot (WB) of anti-TGFBI antibody

Western blot analysis of extracts of various cell lines, using TGFBI antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 5s.
Rabbit Anti-TGFBI Polyclonal Antibody – Cat# MBS128127

Immunohistochemistry (IHC) of anti-TGFBI antibody

Immunohistochemistry of paraffin-embedded human lung cancer using TGFBI antibody at dilution of 1:100 (40x lens).
Rabbit Anti-TGFBI Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS128127

Immunohistochemistry (IHC) of anti-TGFBI antibody

Immunohistochemistry of paraffin-embedded human liver cancer using TGFBI antibody at dilution of 1:100 (40x lens).
Rabbit Anti-TGFBI Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS128127

Immunohistochemistry (IHC) of anti-TGFBI antibody

Immunohistochemistry of paraffin-embedded human colon carcinoma using TGFBI antibody at dilution of 1:100 (40x lens).
Rabbit Anti-TGFBI Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS128127

Immunohistochemistry (IHC) of anti-TGFBI antibody

Immunohistochemistry of paraffin-embedded human gastric cancer using TGFBI antibody at dilution of 1:100 (40x lens).
Rabbit Anti-TGFBI Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS128127

Other Notes

Small volumes of anti-TGFBI antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TGFBI purchase

MBS128127 is an antibody targeting TGFBI. Also known as TGFBI Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TGFBI. It may not necessarily be applicable to this product.

NCBI GI #
2498193
NCBI GeneID
7045
NCBI Accession #
Q15582.1
UniProt Primary Accession #
Q15582
UniProt Secondary Accession #
O14471; O14472; O14476; O43216; O43217; O43218; O43219; Q53XM1; D3DQB1
UniProt Related Accession #
Q15582
NCBI Official Full Name
Transforming growth factor-beta-induced protein ig-h3
NCBI Official Synonym Full Names
transforming growth factor, beta-induced, 68kDa
NCBI Official Symbol
TGFBI
NCBI Official Synonym Symbols
CSD; CDB1; CDG2; CSD1; CSD2; CSD3; EBMD; LCD1; BIGH3; CDGG1
UniProt Protein Name
Transforming growth factor-beta-induced protein ig-h3
UniProt Synonym Protein Names
Kerato-epithelin; RGD-containing collagen-associated protein; RGD-CAP
Protein Family
Transforming growth factor-beta-induced protein
UniProt Gene Name
TGFBI
UniProt Synonym Gene Names
BIGH3; Beta ig-h3; RGD-CAP
UniProt Entry Name
BGH3_HUMAN
NCBI Protein Information
transforming growth factor-beta-induced protein ig-h3; RGD-CAP; beta ig-h3; kerato-epithelin; RGD-containing collagen-associated protein; transforming growth factor, beta-induced, 68kD

UniProt Comments for TGFBI

betaIG-H3: Binds to type I, II, and IV collagens. This adhesion protein may play an important role in cell-collagen interactions. In cartilage, may be involved in endochondral bone formation. By TGFB1. Highly expressed in the corneal epithelium.

Protein type: Secreted, signal peptide; Secreted; Cell adhesion; Extracellular matrix

Chromosomal Location of Human Ortholog: 5q31

Cellular Component: extracellular matrix; proteinaceous extracellular matrix; extracellular space; extracellular region; plasma membrane; basement membrane; trans-Golgi network

Molecular Function: integrin binding; collagen binding; protein binding; extracellular matrix binding

Biological Process: cell proliferation; extracellular matrix organization and biogenesis; visual perception; response to stimulus; chondrocyte differentiation; negative regulation of cell adhesion; angiogenesis; cell adhesion

Disease: Corneal Dystrophy, Epithelial Basement Membrane; Corneal Dystrophy, Lattice Type Iiia; Corneal Dystrophy, Avellino Type; Corneal Dystrophy Of Bowman Layer, Type Ii; Corneal Dystrophy, Lattice Type I; Corneal Dystrophy Of Bowman Layer, Type I; Corneal Dystrophy, Groenouw Type I
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Research Articles on TGFBI

1. This study improves the knowledge of the genetic features of Mexican patients with corneal stromal dystrophies by identifying mutations in the TGFBI, CHST6, and GSN genes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TGFBI antibody

 Reference Product  PubMed Publications
 TGFB1 antibody  >52 publications with TGFBI and TGFB1
 COL1A2 antibody  >6 publications with TGFBI and COL1A2
 CTGF antibody  >4 publications with TGFBI and CTGF
 FN1 antibody  >3 publications with TGFBI and FN1
 SMAD3 antibody  >2 publications with TGFBI and SMAD3
 SMAD2 antibody  >2 publications with TGFBI and SMAD2
 SMAD7 antibody  >1 publications with TGFBI and SMAD7
 VEGFA antibody  >1 publications with TGFBI and VEGFA
 DCN antibody  >1 publications with TGFBI and DCN

Pathways associated with anti-TGFBI antibody

 Products by Pathway  Pathway Diagram
 Amyloids Pathway antibodies  Amyloids Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram

Diseases associated with anti-TGFBI antibody

 Disease Name  Pubmed Publications
 Lattice corneal dystrophy type 1 Antibodies  >9 publications with TGFBI and Lattice corneal dystrophy type 1
 Lung Diseases Antibodies  >9 publications with TGFBI and Lung Diseases
 Corneal Dystrophy, Lattice Type IIIA Antibodies  >9 publications with TGFBI and Corneal Dystrophy, Lattice Type IIIA
 Inflammation Antibodies  >8 publications with TGFBI and Inflammation
 Kidney Diseases Antibodies  >8 publications with TGFBI and Kidney Diseases
 Lung Neoplasms Antibodies  >7 publications with TGFBI and Lung Neoplasms
 Corneal dystrophy Avellino type Antibodies  >7 publications with TGFBI and Corneal dystrophy Avellino type
 Groenouw type I corneal dystrophy Antibodies  >5 publications with TGFBI and Groenouw type I corneal dystrophy
 Pancreatic Neoplasms Antibodies  >5 publications with TGFBI and Pancreatic Neoplasms
 Disease Models, Animal Antibodies  >5 publications with TGFBI and Disease Models, Animal

Organs/Tissues associated with anti-TGFBI antibody

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >127 publications with TGFBI and Eye
 Blood Antibodies  >54 publications with TGFBI and Blood
 Bone Antibodies  >17 publications with TGFBI and Bone
 Lung Antibodies  >12 publications with TGFBI and Lung
 Brain Antibodies  >10 publications with TGFBI and Brain
 Kidney Antibodies  >9 publications with TGFBI and Kidney
 Skin Antibodies  >7 publications with TGFBI and Skin
 Muscle Antibodies  >7 publications with TGFBI and Muscle
 Bone Marrow Antibodies  >7 publications with TGFBI and Bone Marrow
 Liver Antibodies  >7 publications with TGFBI and Liver
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