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UGT1A9 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS128155
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This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
UGT1A9, Polyclonal Antibody
Full Product Name
UGT1A9 Polyclonal Antibody
Product Gene Name
anti-UGT1A9 antibody
Product Synonym Names
LUGP4; UDPGT; UGT1I; HLUGP4; UGT-1I; UGT1-9; UGT1.9; UGT1AI; UGT1-09; UDPGT 1-9
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
530
OMIM
gene 606434
3D Structure
ModBase 3D Structure for O60656
Species
Human
Immunogen
Recombinant protein of human UGT1A9
Calculated Molecular Weight
60kDa

Product Categories/Family for anti-UGT1A9 antibody

Polyclonal
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-UGT1A9 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-UGT1A9 antibody
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200

Western Blot (WB) of anti-UGT1A9 antibody

Western blot analysis of extracts of various cell lines, using UGT1A9 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Rabbit Anti-UGT1A9 Polyclonal Antibody – Cat# MBS128155

Immunohistochemistry (IHC) of anti-UGT1A9 antibody

Immunohistochemistry of paraffin-embedded human liver cancer using UGT1A9 antibody at dilution of 1:200 (40x lens).
Rabbit Anti-UGT1A9 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS128155

Immunofluorescence (IF) of anti-UGT1A9 antibody

Immunofluorescence analysis of MCF-7 cells using UGT1A9 antibody. Blue: DAPI for nuclear staining.
Rabbit Anti-UGT1A9 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS128155

Other Notes

Small volumes of anti-UGT1A9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for UGT1A9 purchase

MBS128155 is an antibody targeting UGT1A9. Also known as UGT1A9 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for UGT1A9. It may not necessarily be applicable to this product.

NCBI GI #
29839451
NCBI GeneID
54600
NCBI Accession #
O60656.1
UniProt Primary Accession #
O60656
UniProt Secondary Accession #
P36509; Q9HAX0; B8K285
UniProt Related Accession #
O60656
NCBI Official Full Name
UDP-glucuronosyltransferase 1-9
NCBI Official Synonym Full Names
UDP glucuronosyltransferase 1 family, polypeptide A9
NCBI Official Symbol
UGT1A9
NCBI Official Synonym Symbols
LUGP4; UDPGT; UGT1I; HLUGP4; UGT-1I; UGT1-9; UGT1.9; UGT1AI; UGT1-09; UDPGT 1-9
UniProt Protein Name
UDP-glucuronosyltransferase 1-9
UniProt Synonym Protein Names
UDP-glucuronosyltransferase 1-I; UGT-1I; UGT1I; UDP-glucuronosyltransferase 1A9; lugP4
Protein Family
UDP-glucuronosyltransferase
UniProt Gene Name
UGT1A9
UniProt Synonym Gene Names
GNT1; UGT1; UDPGT 1-9; UGT1*9; UGT1-09; UGT1.9; UGT-1I; UGT1I
UniProt Entry Name
UD19_HUMAN
NCBI Protein Information
UDP-glucuronosyltransferase 1-9; UDP-glucuronosyltransferase 1-I; UDP-glucuronosyltransferase 1A9; UDP glycosyltransferase 1 family, polypeptide A9

UniProt Comments for UGT1A9

UGT1A9: UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols. Belongs to the UDP-glycosyltransferase family. 1 isoforms of the human protein are produced by alternative splicing.

Protein type: Endoplasmic reticulum; Transferase; Xenobiotic Metabolism - metabolism by cytochrome P450; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; Carbohydrate Metabolism - starch and sucrose; Lipid Metabolism - androgen and estrogen; Xenobiotic Metabolism - drug metabolism - other enzymes; EC 2.4.1.17; Carbohydrate Metabolism - pentose and glucuronate interconversions; Membrane protein, integral; Carbohydrate Metabolism - ascorbate and aldarate; Cofactor and Vitamin Metabolism - retinol

Chromosomal Location of Human Ortholog: 2q37

Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; integral to membrane

Molecular Function: enzyme inhibitor activity; protein homodimerization activity; enzyme binding; retinoic acid binding; protein heterodimerization activity; glucuronosyltransferase activity

Biological Process: negative regulation of transferase activity; flavonoid biosynthetic process; metabolic process; xenobiotic metabolic process; flavone metabolic process; retinoic acid metabolic process; cellular lipid metabolic process; negative regulation of fatty acid metabolic process; drug metabolic process; cellular response to hormone stimulus
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Research Articles on UGT1A9

1. UGT1A9 is the major isoform responsible for the glucuronidations of fraxetin in liver microsomes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-UGT1A9 antibody

 Reference Product  PubMed Publications
 CYP3A4 antibody  >39 publications with UGT1A9 and CYP3A4
 CYP2C9 antibody  >32 publications with UGT1A9 and CYP2C9
 CYP1A2 antibody  >27 publications with UGT1A9 and CYP1A2
 CYP2C19 antibody  >18 publications with UGT1A9 and CYP2C19
 CYP2B6 antibody  >18 publications with UGT1A9 and CYP2B6
 CYP3A5 antibody  >16 publications with UGT1A9 and CYP3A5
 CYP1A1 antibody  >8 publications with UGT1A9 and CYP1A1
 CYP2A6 antibody  >7 publications with UGT1A9 and CYP2A6
 CYP1B1 antibody  >2 publications with UGT1A9 and CYP1B1

Pathways associated with anti-UGT1A9 antibody

 Products by Pathway  Pathway Diagram
 Arylamine Metabolism Pathway antibodies  Arylamine Metabolism Pathway Diagram
 Ascorbate And Aldarate Metabolism Pathway antibodies  Ascorbate And Aldarate Metabolism Pathway Diagram
 Ascorbate And Aldarate Metabolism Pathway antibodies  Ascorbate And Aldarate Metabolism Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Defective AHCY Causes Hypermethioninemia With S-adenosylhomocysteine Hydrolase Deficiency (HMAHCHD) Pathway antibodies  Defective AHCY Causes Hypermethioninemia With S-adenosylhomocysteine Hydrolase Deficiency (HMAHCHD) Pathway Diagram
 Defective GCLC Causes Hemolytic Anemia Due To Gamma-glutamylcysteine Synthetase Deficiency (HAGGSD) Pathway antibodies  Defective GCLC Causes Hemolytic Anemia Due To Gamma-glutamylcysteine Synthetase Deficiency (HAGGSD) Pathway Diagram
 Defective GGT1 Causes Glutathionuria (GLUTH) Pathway antibodies  Defective GGT1 Causes Glutathionuria (GLUTH) Pathway Diagram
 Defective GSS Causes Glutathione Synthetase Deficiency (GSS Deficiency) Pathway antibodies  Defective GSS Causes Glutathione Synthetase Deficiency (GSS Deficiency) Pathway Diagram

Diseases associated with anti-UGT1A9 antibody

 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >25 publications with UGT1A9 and Liver Diseases
 Liver Neoplasms Antibodies  >16 publications with UGT1A9 and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >13 publications with UGT1A9 and Carcinoma, Hepatocellular
 Fatty Liver Antibodies  >10 publications with UGT1A9 and Fatty Liver
 Kidney Diseases Antibodies  >9 publications with UGT1A9 and Kidney Diseases
 Drug-Related Side Effects and Adverse Reactions Antibodies  >7 publications with UGT1A9 and Drug-Related Side Effects and Adverse Reactions
 Colonic Neoplasms Antibodies  >6 publications with UGT1A9 and Colonic Neoplasms
 Hypertension Antibodies  >6 publications with UGT1A9 and Hypertension
 Cardiovascular Diseases Antibodies  >6 publications with UGT1A9 and Cardiovascular Diseases
 Nervous System Diseases Antibodies  >5 publications with UGT1A9 and Nervous System Diseases

Organs/Tissues associated with anti-UGT1A9 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >291 publications with UGT1A9 and Liver
 Kidney Antibodies  >81 publications with UGT1A9 and Kidney
 Intestine Antibodies  >58 publications with UGT1A9 and Intestine
 Lung Antibodies  >13 publications with UGT1A9 and Lung
 Bladder Antibodies  >6 publications with UGT1A9 and Bladder
 Stomach Antibodies  >5 publications with UGT1A9 and Stomach
 Brain Antibodies  >5 publications with UGT1A9 and Brain
 Prostate Antibodies  >4 publications with UGT1A9 and Prostate
 Embryonic Tissue Antibodies  >3 publications with UGT1A9 and Embryonic Tissue
 Esophagus Antibodies  >3 publications with UGT1A9 and Esophagus
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