• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

GAP43 Antibody – Rabbit

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS128254
SPECIAL PROMOTION: Get FREE $5 Amazon gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment

The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective… More details

$245 / 0.02 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GAP43-S41, Antibody
Full Product Name
Phospho-GAP43-S41 Polyclonal Antibody
Product Gene Name
anti-GAP43 antibody
Product Synonym Names
Phospho-GAP43-S41: B-50; PP46
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
238
OMIM
162060
3D Structure
ModBase 3D Structure for P17677
Species
Human
Route
Synthetic Peptide
Immunogen
A phospho specific peptide corresponding to residues surrounding S41 of human GAP43
Calculated Molecular Weight
43kDa

Product Categories/Family for anti-GAP43 antibody

Phosphorylation
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-GAP43 antibody
Immunofluorescence (IF)
Application Notes for anti-GAP43 antibody
IF: 1:100 - 1:200

Immunofluorescence (IF) of anti-GAP43 antibody

Immunofluorescence staining of methanol-fixed HeLa cells using Phospho-GAP43-S41 antibody.
Rabbit Anti-GAP43 Antibody – Cat# MBS128254

Other Notes

Small volumes of anti-GAP43 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GAP43 purchase

MBS128254 is an antibody targeting GAP43. Also known as Phospho-GAP43-S41 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GAP43. It may not necessarily be applicable to this product.

NCBI GI #
128100
NCBI GeneID
2596
NCBI Accession #
P17677.1
UniProt Primary Accession #
P17677
UniProt Secondary Accession #
A8K0Y4
UniProt Related Accession #
P17677
NCBI Official Full Name
Neuromodulin
NCBI Official Synonym Full Names
growth associated protein 43
NCBI Official Symbol
GAP43
NCBI Official Synonym Symbols
B-50; PP46
UniProt Protein Name
Neuromodulin
UniProt Synonym Protein Names
Axonal membrane protein GAP-43; Growth-associated protein 43; Neural phosphoprotein B-50; pp46
Protein Family
Neuromodulin
UniProt Gene Name
GAP43
UniProt Entry Name
NEUM_HUMAN
NCBI Protein Information
neuromodulin; protein F1; neural phosphoprotein B-50; growth-associated protein 43; axonal membrane protein GAP-43; calmodulin-binding protein P-57; nerve growth-related peptide GAP43; neuron growth-associated protein 43

UniProt Comments for GAP43

GAP43: This protein is associated with nerve growth. It is a major component of the motile growth cones that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction. Identified in a complex containing FGFR4, NCAM1, CDH2, PLCG1, FRS2, SRC, SHC1, GAP43 and CTTN. Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence. Belongs to the neuromodulin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell surface

Chromosomal Location of Human Ortholog: 3q13.31

Cellular Component: filopodium membrane; axon; cytoplasm; postsynaptic density; plasma membrane; cell junction

Molecular Function: calmodulin binding; protein binding

Biological Process: cell fate commitment; glial cell differentiation; tissue regeneration; regulation of growth; protein kinase C activation; axon choice point recognition; response to wounding; regulation of filopodium formation
Show more

Research Articles on GAP43

1. GAP43 is seemingly a highly sensitive marker for peripheral nerve sheath tumors

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GAP43 antibody

 Reference Product  PubMed Publications
 SYP antibody  >10 publications with GAP43 and SYP
 CNTF antibody  >8 publications with GAP43 and CNTF
 ELAVL4 antibody  >1 publications with GAP43 and ELAVL4

Pathways associated with anti-GAP43 antibody

 Products by Pathway  Pathway Diagram
 Glial Cell Differentiation Pathway antibodies  Glial Cell Differentiation Pathway Diagram
 N-cadherin Signaling Events Pathway antibodies  N-cadherin Signaling Events Pathway Diagram
 Spinal Cord Injury Pathway antibodies  Spinal Cord Injury Pathway Diagram

Diseases associated with anti-GAP43 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >131 publications with GAP43 and Nervous System Diseases
 Disease Models, Animal Antibodies  >65 publications with GAP43 and Disease Models, Animal
 Brain Diseases Antibodies  >59 publications with GAP43 and Brain Diseases
 Cardiovascular Diseases Antibodies  >46 publications with GAP43 and Cardiovascular Diseases
 Heart Diseases Antibodies  >31 publications with GAP43 and Heart Diseases
 Nerve Degeneration Antibodies  >23 publications with GAP43 and Nerve Degeneration
 Brain Injuries Antibodies  >23 publications with GAP43 and Brain Injuries
 Inflammation Antibodies  >22 publications with GAP43 and Inflammation
 Pain Antibodies  >22 publications with GAP43 and Pain
 Necrosis Antibodies  >9 publications with GAP43 and Necrosis

Organs/Tissues associated with anti-GAP43 antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >266 publications with GAP43 and Nerve
 Brain Antibodies  >223 publications with GAP43 and Brain
 Eye Antibodies  >30 publications with GAP43 and Eye
 Embryonic Tissue Antibodies  >29 publications with GAP43 and Embryonic Tissue
 Vascular Antibodies  >17 publications with GAP43 and Vascular
 Bone Antibodies  >17 publications with GAP43 and Bone
 Connective Tissue Antibodies  >3 publications with GAP43 and Connective Tissue
 Lung Antibodies  >2 publications with GAP43 and Lung
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000