• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

MYL12A Antibody – Rabbit

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS128273
SPECIAL PROMOTION: Get FREE $5 Amazon gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment

MBS128273 is an antibody targeting MYL12A. Also known as Phospho-MYL12A-S18 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$245 / 0.02 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MYL12A-S18, Antibody
Full Product Name
Phospho-MYL12A-S18 Polyclonal Antibody
Product Gene Name
Product Synonym Names
Phospho-MYL12A-S18: MLCB; MRCL3; MRLC3; MYL2B
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
171
OMIM
609211
3D Structure
ModBase 3D Structure for P19105
Species
Human
Route
Synthetic Peptide
Immunogen
A phospho specific peptide corresponding to residues surrounding S18 of human MYL12A
Calculated Molecular Weight
18kDa

Product Categories/Family for anti-MYL12A antibody

ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-MYL12A antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-MYL12A antibody
WB: 1:500 - 1:2000
IHC: 1:50 - 1:100

Western Blot (WB) of anti-MYL12A antibody

Western blot analysis of extracts from 293 cells untreated or treated with starvation using Phospho-MYL12A-S18 antibody.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% BSA.
Rabbit Anti-MYL12A Antibody – Cat# MBS128273

Immunohistochemistry (IHC) of anti-MYL12A antibody

Immunohistochemistry of paraffin-embedded human breast carcinoma using Phospho-MYL12A-S18 antibody.
Rabbit Anti-MYL12A Antibody, Immunohistochemistry (IHC) – Cat# MBS128273

Other Notes

Small volumes of anti-MYL12A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MYL12A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Myosin regulatory light chain 12A
NCBI Official Synonym Full Names
myosin, light chain 12A, regulatory, non-sarcomeric
NCBI Official Symbol
MYL12A
NCBI Official Synonym Symbols
MLCB; MRCL3; MRLC3; MYL2B; MLC-2B; HEL-S-24
UniProt Protein Name
Myosin regulatory light chain 12A
UniProt Synonym Protein Names
Epididymis secretory protein Li 24; HEL-S-24; MLC-2B; Myosin RLC; Myosin regulatory light chain 2, nonsarcomeric; Myosin regulatory light chain MRLC3
Protein Family
UniProt Gene Name
MYL12A
UniProt Synonym Gene Names
MLCB; MRLC3; RLC; HEL-S-24
UniProt Entry Name
ML12A_HUMAN
NCBI Protein Information
myosin regulatory light chain 12A; myosin RLC; myosin regulatory light chain 3; epididymis secretory protein Li 24; myosin regulatory light chain MRLC3; myosin regulatory light chain 2, nonsarcomeric; myosin, light polypeptide, regulatory, non-sarcomeric (20kD)

NCBI Summary for MYL12A

This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8.[provided by RefSeq, Dec 2014]
Show more

UniProt Comments for MYL12A

MRLC3: Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion. Myosin is an hexamer of 2 heavy chains and 4 light chains.

Protein type: Contractile

Chromosomal Location of Human Ortholog: 18p11.31

Cellular Component: myosin II complex; stress fiber; cytosol; Z disc

Molecular Function: protein binding; glutamate receptor binding; calcium ion binding

Biological Process: axon guidance; regulation of cell shape; ephrin receptor signaling pathway
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MYL12A antibody

Organs/Tissues associated with anti-MYL12A antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >2 publications with MYL12A and Muscle
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000