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Ribosomal RNA-Processing Protein 8 (RRP8) Rat Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1282965

MBS1282965 is a recombinant protein targeting Rrp8. Also known as Recombinant Rat Ribosomal RNA-processing protein 8 (Rrp8). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1230 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Ribosomal RNA-processing protein 8 (Rrp8), Recombinant Protein
Full Product Name
Recombinant Rat Ribosomal RNA-processing protein 8 (Rrp8)
Product Gene Name
Product Synonym Gene Name
Rrp8
Sequence
MFEEPEWVEA APAIVGLRPV TTQVQAATAP PVKGRKRRHL LATLRALEAA SLSQQCPSLP GSDSEEEEEV GRKKRHFQRS SLANVSKEVG KKRKGKCQKQ APFISDSEGK EVERTCHRQA PPLGGISAGE EKGKRKCQEY SYLHPTQSLN SVDQTVHNSR TSTATLDPPK SSRESASPNS SHTLSRKQWR NRQKNKRRHK NKFRPLETQD QVPLKASIEE TEVPPAPKSD SQETRAGALR ARMTQRLDGA RFRYLNEQLY SGPSSAAQCL FQEDPEAFLL YHRGFQRQVK KWPLHPVDRI AKDLRQKPAS LVVADFGCGD CRLASSVRNP VHCFDLAALD PRVTVCDMAQ VPLEDESVDV AVFCLSLMGT NIRDFLEEAN RVLKPGGLLK VAEVSSRFED IRTFLGAVTK LGFKVIYKDL TNSHFFLFDF EKTGPPRVGP KAQLSGLKLQ PCLYKHR
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
51,216 Da
Sequence Positions
1-457, full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q5U4F0
Species
Rat
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Rrp8 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Rrp8. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ribosomal RNA-processing protein 8
NCBI Official Synonym Full Names
ribosomal RNA processing 8
NCBI Official Symbol
Rrp8
NCBI Official Synonym Symbols
RGD1308302
UniProt Protein Name
Ribosomal RNA-processing protein 8
UniProt Synonym Protein Names
Cerebral protein 1 homolog
Protein Family
UniProt Gene Name
Rrp8
NCBI Protein Information
ribosomal RNA-processing protein 8

UniProt Comments for Rrp8

Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD+/NADP+ ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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