Rabbit Anti-EFNB2 Antibody – Cat# MBS128434

Western blot analysis of extracts from HT29 cells, using Phospho-EFNB2-Y316 antibody.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% BSA.

EFNB2 Antibody – Rabbit

Name: EFNB2 Antibody; Rabbit; Human/Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS128434
Price: 440 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS128434

This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

EFNB2-Y316, Antibody

Full Product Name

Phospho-EFNB2-Y316 Polyclonal Antibody

Product Gene Name

anti-EFNB2 antibody

Product Synonym Names

Phospho-EFNB2-Y316: HTKL; EPLG5; Htk-L; LERK5

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse

Purity/Purification

Affinity Purification

Concentration

1mg/ml (lot specific)

Preparation and Storage

Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

333

OMIM

600527

3D Structure

ModBase 3D Structure for P52799

Species

Human

Route

Synthetic Peptide

Immunogen

A phospho specific peptide corresponding to residues surrounding Y316 of human EFNB2

Calculated Molecular Weight

37kDa

Product Categories/Family for anti-EFNB2 antibody

Phosphorylation

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-EFNB2 antibody

Western Blot (WB)

Application Notes for anti-EFNB2 antibody

WB: 1:500 - 1:2000

Other Notes

Small volumes of anti-EFNB2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EFNB2 purchase

MBS128434 is an antibody targeting EFNB2. Also known as Phospho-EFNB2-Y316 Polyclonal Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for EFNB2. It may not necessarily be applicable to this product.

NCBI GI #

1706673

NCBI GeneID

1948

NCBI Accession #

P52799.1

UniProt Primary Accession #

P52799

UniProt Secondary Accession #

Q5JV56

UniProt Related Accession #

P52799

NCBI Official Full Name

Ephrin-B2

NCBI Official Synonym Full Names

ephrin-B2

NCBI Official Symbol

EFNB2

NCBI Official Synonym Symbols

HTKL; EPLG5; Htk-L; LERK5

UniProt Protein Name

Ephrin-B2

UniProt Synonym Protein Names

EPH-related receptor tyrosine kinase ligand 5; LERK-5; HTK ligand; HTK-L

Protein Family

Ephrin

UniProt Gene Name

EFNB2

UniProt Synonym Gene Names

EPLG5; HTKL; LERK5; LERK-5; HTK-L

UniProt Entry Name

EFNB2_HUMAN

NCBI Protein Information

ephrin-B2; LERK-5; HTK ligand; ligand of eph-related kinase 5; eph-related receptor tyrosine kinase ligand 5

UniProt Comments for EFNB2

EFNB2: a type I membrane protein of the ephrin family. A ligand of Eph-related receptor tyrosine kinases EphA3 and EphB4. Ephrins and ephrin receptors mediate numerous developmental processes, particularly in the nervous system. Ephrin-B2 is implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. May play a role in constraining the orientation of longitudinally projecting axons

Protein type: Ligand, receptor tyrosine kinase; Membrane protein, integral

Chromosomal Location of Human Ortholog: 13q33

Cellular Component: focal adhesion; integral to plasma membrane; plasma membrane

Molecular Function: protein binding; ephrin receptor binding

Biological Process: axon guidance; organ morphogenesis; anatomical structure morphogenesis; regulation of chemotaxis; viral reproduction; cell-cell signaling; cell migration during sprouting angiogenesis; ephrin receptor signaling pathway; cell adhesion; lymph vessel development

Research Articles on EFNB2

1. Downregulation of the endothelial genes Notch1 and ephrinB2 in patients with nodular regenerative hyperplasia.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-EFNB2 antibody

Reference Product	PubMed Publications
EPHB4 antibody	>16 publications with EFNB2 and EPHB4
EPHB2 antibody	>10 publications with EFNB2 and EPHB2
EPHB6 antibody	>8 publications with EFNB2 and EPHB6
EPHB1 antibody	>4 publications with EFNB2 and EPHB1
EPHA4 antibody	>4 publications with EFNB2 and EPHA4
EPHA6 antibody	>1 publications with EFNB2 and EPHA6
EPHB3 antibody	>1 publications with EFNB2 and EPHB3
SRC antibody	>1 publications with EFNB2 and SRC

Pathways associated with anti-EFNB2 antibody

Products by Pathway	Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
EPH-Ephrin Signaling Pathway antibodies	EPH-Ephrin Signaling Pathway Diagram
EPH-ephrin Mediated Repulsion Of Cells Pathway antibodies	EPH-ephrin Mediated Repulsion Of Cells Pathway Diagram
EPHB Forward Signaling Pathway antibodies	EPHB Forward Signaling Pathway Diagram
EPHB-mediated Forward Signaling Pathway antibodies	EPHB-mediated Forward Signaling Pathway Diagram
Ephrin B Reverse Signaling Pathway antibodies	Ephrin B Reverse Signaling Pathway Diagram
Ephrin Signaling Pathway antibodies	Ephrin Signaling Pathway Diagram

Diseases associated with anti-EFNB2 antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>9 publications with EFNB2 and Nervous System Diseases
Cardiovascular Diseases Antibodies	>8 publications with EFNB2 and Cardiovascular Diseases
Disease Models, Animal Antibodies	>6 publications with EFNB2 and Disease Models, Animal
Adenocarcinoma Antibodies	>4 publications with EFNB2 and Adenocarcinoma
Lung Diseases Antibodies	>3 publications with EFNB2 and Lung Diseases
Heart Diseases Antibodies	>3 publications with EFNB2 and Heart Diseases
Neoplasms, Experimental Antibodies	>2 publications with EFNB2 and Neoplasms, Experimental
Necrosis Antibodies	>2 publications with EFNB2 and Necrosis
Heart Defects, Congenital Antibodies	>2 publications with EFNB2 and Heart Defects, Congenital
Lung Neoplasms Antibodies	>2 publications with EFNB2 and Lung Neoplasms

Organs/Tissues associated with anti-EFNB2 antibody

Organ/Tissue Name	Pubmed Publications
Vascular Antibodies	>26 publications with EFNB2 and Vascular
Blood Antibodies	>21 publications with EFNB2 and Blood
Brain Antibodies	>13 publications with EFNB2 and Brain
Bone Antibodies	>12 publications with EFNB2 and Bone
Embryonic Tissue Antibodies	>11 publications with EFNB2 and Embryonic Tissue
Eye Antibodies	>7 publications with EFNB2 and Eye
Heart Antibodies	>7 publications with EFNB2 and Heart
Liver Antibodies	>4 publications with EFNB2 and Liver
Thymus Antibodies	>4 publications with EFNB2 and Thymus
Spleen Antibodies	>4 publications with EFNB2 and Spleen