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PRSS8 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS128647
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This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The proprotein is cleaved to produce a light… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PRSS8, Polyclonal Antibody
Full Product Name
PRSS8 Polyclonal Antibody
Product Gene Name
Product Synonym Names
CAP1; PROSTASIN
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
343
OMIM
600823
3D Structure
ModBase 3D Structure for Q16651
Species
Human
Immunogen
Recombinant protein of human PRSS8
Calculated Molecular Weight
36kDa

Product Categories/Family for anti-PRSS8 antibody

ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PRSS8 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-PRSS8 antibody
WB: 1:200-1:2000
IHC: 1:50-1:200

Western Blot (WB) of anti-PRSS8 antibody

Western blot analysis of extracts of MDA-MB-453 cells, using PRSS8 antibody.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Rabbit Anti-PRSS8 Polyclonal Antibody – Cat# MBS128647

Other Notes

Small volumes of anti-PRSS8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PRSS8 purchase

MBS128647 is an antibody targeting PRSS8. Also known as PRSS8 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PRSS8. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Prostasin
NCBI Official Synonym Full Names
protease, serine, 8
NCBI Official Symbol
PRSS8
NCBI Official Synonym Symbols
CAP1; PROSTASIN
UniProt Protein Name
Prostasin
UniProt Synonym Protein Names
Channel-activating protease 1; CAP1; Serine protease 8Cleaved into the following 2 chains:Prostasin light chain; Prostasin heavy chain
Protein Family
UniProt Gene Name
PRSS8
UniProt Synonym Gene Names
CAP1
UniProt Entry Name
PRSS8_HUMAN
NCBI Protein Information
prostasin; serine protease 8; channel-activating protease 1

UniProt Comments for PRSS8

PRSS8: Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G). Belongs to the peptidase S1 family.

Protein type: Membrane protein, integral; EC 3.4.21.-; Protease

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: extracellular space; plasma membrane; integral to membrane; extracellular region

Molecular Function: protein binding; serine-type peptidase activity; serine-type endopeptidase activity

Biological Process: proteolysis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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