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Sorting Nexin-15 (SNX15) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1287058

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the… More details

$1055 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Sorting nexin-15 (SNX15), Recombinant Protein
Full Product Name
Recombinant Human Sorting nexin-15 (SNX15)
Product Gene Name
SNX15 recombinant protein
Product Synonym Gene Name
SNX15
Sequence
MSRQAKDDFL RHYTVSDPRT HPKGYTEYKV TAQFISKKDP EDVKEVVVWK RYSDFRKLHG DLAYTHRNLF RRLEEFPAFP RAQVFGRFEA SVIEERRKGA EDLLRFTVHI PALNNSPQLK EFFRGGEVTR PLEVSRDLHI LPPPLIPTPP PDDPRLSQLL PAERRGLEEL EVPVDPPPSS PAQEALDLLF NCESTEEASG SPARGPLTEA ELALFDPFSK EEGAAPSPTH VAELATMEVE SARLDQEPWE PGGQEEEEDG EGGPTPAYLS QATELITQAL RDEKAGAYAA ALQGYRDGVH VLLQGVPSDP LPARQEGVKK KAAEYLKRAE EILRLHLSQL PP
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
29,220 Da
Sequence Positions
1-342, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
605964
3D Structure
ModBase 3D Structure for Q9NRS6
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of SNX15 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SNX15 purchase

MBS1287058 is a recombinant protein targeting SNX15. Also known as Recombinant Human Sorting nexin-15 (SNX15). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for SNX15. It may not necessarily be applicable to this product.

NCBI GI #
22547191
NCBI GeneID
29907
NCBI Accession #
NP_037438.2
UniProt Primary Accession #
Q9NRS6
UniProt Secondary Accession #
Q9NRS5; E5KQS6
UniProt Related Accession #
Q9NRS6
GenBank Nucleotide #
NM_013306.4
NCBI Official Full Name
sorting nexin-15 isoform A
NCBI Official Synonym Full Names
sorting nexin 15
NCBI Official Symbol
SNX15
NCBI Official Synonym Symbols
HSAF001435
UniProt Protein Name
Sorting nexin-15
Protein Family
Sorting nexin
UniProt Gene Name
SNX15
NCBI Protein Information
sorting nexin-15

NCBI Summary for SNX15

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene. [provided by RefSeq, Dec 2010]
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UniProt Comments for SNX15

May be involved in several stages of intracellular trafficking. Overexpression of SNX15 disrupts the normal trafficking of proteins from the plasma membrane to recycling endosomes or the TGN.

Research Articles on SNX15

1. SNX15 regulates the recycling of APP to cell surface and, thus, its processing for Abeta generation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with SNX15 recombinant protein

 Reference Product  PubMed Publications
 SNX1 recombinant protein  >1 publications with SNX15 and SNX1

Pathways associated with SNX15 recombinant protein

 Products by Pathway  Pathway Diagram
 PDGFR-beta Signaling Pathway antibodies  PDGFR-beta Signaling Pathway Diagram

Diseases associated with SNX15 recombinant protein

 Disease Name  Pubmed Publications
 Wasting Syndrome Antibodies  >1 publications with SNX15 and Wasting Syndrome

Organs/Tissues associated with SNX15 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >1 publications with SNX15 and Nerve
 Muscle Antibodies  >1 publications with SNX15 and Muscle
 Lung Antibodies  >1 publications with SNX15 and Lung
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