Rabbit Anti-PTGES2 Polyclonal Antibody – Cat# MBS128760

Western blot analysis of extracts of mouse brain, using PTGES2 antibody.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.

PTGES2 Antibody – Rabbit Polyclonal

Name: PTGES2 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS128760
Price: 360 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS128760

The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

PTGES2, Polyclonal Antibody

Full Product Name

PTGES2 Polyclonal Antibody

Product Gene Name

anti-PTGES2 antibody

Product Synonym Names

GBF1; GBF-1; PGES2; C9orf15; mPGES-2

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Purity/Purification

Affinity Purification

Concentration

1mg/ml (lot specific)

Preparation and Storage

Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

377

OMIM

608152

3D Structure

ModBase 3D Structure for Q9H7Z7

Species

Human

Immunogen

Recombinant protein of human PTGES2

Calculated Molecular Weight

42kDa

Product Categories/Family for anti-PTGES2 antibody

Polyclonal

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-PTGES2 antibody

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Application Notes for anti-PTGES2 antibody

WB: 1:200-1:2000
IHC: 1:50-1:200
IF: 1:50-1:100

Other Notes

Small volumes of anti-PTGES2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PTGES2 purchase

MBS128760 is an antibody targeting PTGES2. Also known as PTGES2 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PTGES2. It may not necessarily be applicable to this product.

NCBI GI #

73921741

NCBI GeneID

80142

NCBI Accession #

Q9H7Z7.1

UniProt Primary Accession #

Q9H7Z7

UniProt Secondary Accession #

Q53EW9; Q5SYV6; Q96GI0; Q96GL2

UniProt Related Accession #

Q9H7Z7

NCBI Official Full Name

Prostaglandin E synthase 2

NCBI Official Synonym Full Names

prostaglandin E synthase 2

NCBI Official Symbol

PTGES2

NCBI Official Synonym Symbols

GBF1; GBF-1; PGES2; C9orf15; mPGES-2

UniProt Protein Name

Prostaglandin E synthase 2

UniProt Synonym Protein Names

Membrane-associated prostaglandin E synthase-2; Microsomal prostaglandin E synthase 2

Protein Family

Prostaglandin E synthase

UniProt Gene Name

PTGES2

UniProt Entry Name

PGES2_HUMAN

NCBI Protein Information

prostaglandin E synthase 2; mPGE synthase-2; GATE-binding factor 1; prostaglandin-H(2) E-isomerase; microsomal prostaglandin E synthase-2; membrane-associated prostaglandin E synthase 2; membrane-associated prostaglandin E synthase-2; gamma-interferon-activated transcriptional element-binding factor 1

UniProt Comments for PTGES2

PTGES2: Isomerase that catalyzes the conversion of unstable intermediate of prostaglandin E2 H2 (PGH2) into the more stable prostaglandin E2 (PGE2) form. May also have transactivation activity toward IFN-gamma (IFNG), possibly via an interaction with CEBPB; however, the relevance of transcription activation activity remains unclear. Belongs to the GST superfamily.

Protein type: Membrane protein, integral; Lipid Metabolism - arachidonic acid; Isomerase; EC 5.3.99.3

Chromosomal Location of Human Ortholog: 9q34.11

Cellular Component: Golgi membrane; mitochondrion; perinuclear region of cytoplasm; integral to membrane; cytosol; nucleus

Molecular Function: DNA binding; glutathione binding; electron carrier activity; protein disulfide oxidoreductase activity; lyase activity; heme binding; prostaglandin-E synthase activity

Biological Process: secretion; cell redox homeostasis; positive regulation of transcription, DNA-dependent; prostaglandin biosynthetic process

Research Articles on PTGES2

1. Four single nucleotide polymorphisms in two genes in the PGE2 family, PTGES2 and PTGER4, were significantly associated with primary graft dysfunction after lung transplantation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PTGES2 antibody

Reference Product	PubMed Publications
PTGS2 antibody	>10 publications with PTGES2 and PTGS2
PTGES antibody	>7 publications with PTGES2 and PTGES
PTGS1 antibody	>5 publications with PTGES2 and PTGS1
CBR1 antibody	>2 publications with PTGES2 and CBR1
PTGIS antibody	>2 publications with PTGES2 and PTGIS
HPGDS antibody	>1 publications with PTGES2 and HPGDS
TBXAS1 antibody	>1 publications with PTGES2 and TBXAS1
PTGDS antibody	>1 publications with PTGES2 and PTGDS

Pathways associated with anti-PTGES2 antibody

Products by Pathway	Pathway Diagram
Arachidonic Acid Metabolism Pathway antibodies	Arachidonic Acid Metabolism Pathway Diagram
Arachidonic Acid Metabolism Pathway antibodies	Arachidonic Acid Metabolism Pathway Diagram
C20 Prostanoid Biosynthesis Pathway antibodies	C20 Prostanoid Biosynthesis Pathway Diagram
C20 Prostanoid Biosynthesis Pathway antibodies	C20 Prostanoid Biosynthesis Pathway Diagram
Eicosanoid Synthesis Pathway antibodies	Eicosanoid Synthesis Pathway Diagram
IFN-gamma Pathway antibodies	IFN-gamma Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram

Diseases associated with anti-PTGES2 antibody

Disease Name	Pubmed Publications
Carcinoma Antibodies	>2 publications with PTGES2 and Carcinoma
Obesity Antibodies	>2 publications with PTGES2 and Obesity
Disease Models, Animal Antibodies	>1 publications with PTGES2 and Disease Models, Animal
Anoxia Antibodies	>1 publications with PTGES2 and Anoxia
Neoplasms, Experimental Antibodies	>1 publications with PTGES2 and Neoplasms, Experimental
Insulin Resistance Antibodies	>1 publications with PTGES2 and Insulin Resistance
Prenatal Exposure Delayed Effects Antibodies	>1 publications with PTGES2 and Prenatal Exposure Delayed Effects
Inflammation Antibodies	>1 publications with PTGES2 and Inflammation

Organs/Tissues associated with anti-PTGES2 antibody

Organ/Tissue Name	Pubmed Publications
Uterus Antibodies	>4 publications with PTGES2 and Uterus
Blood Antibodies	>3 publications with PTGES2 and Blood
Embryonic Tissue Antibodies	>2 publications with PTGES2 and Embryonic Tissue
Vascular Antibodies	>1 publications with PTGES2 and Vascular
Ovary Antibodies	>1 publications with PTGES2 and Ovary
Mammary Gland Antibodies	>1 publications with PTGES2 and Mammary Gland
Prostate Antibodies	>1 publications with PTGES2 and Prostate
Lung Antibodies	>1 publications with PTGES2 and Lung