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GNB5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS128782
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Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes… More details

$225 / 0.02 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GNB5, Polyclonal Antibody
Full Product Name
GNB5 Polyclonal Antibody
Product Gene Name
anti-GNB5 antibody
Product Synonym Names
GNB5; GB5; IDDCA; LADCI
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Purity/Purification
Affinity Purification
Preparation and Storage
Store at -20°C. Avoid freeze / thaw cycles.
Molecular Weight
Observed MW: 39kDa
Calculated MW: 31kDa/38kDa/43kDa
OMIM
604447
3D Structure
ModBase 3D Structure for O14775
Immunogen
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human GNB5 (NP_006569.1).

Product Categories/Family for anti-GNB5 antibody

Polyclonal
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-GNB5 antibody
Western Blot (WB)
Application Notes for anti-GNB5 antibody
WB: 1:500 - 1:2000

Western Blot (WB) of anti-GNB5 antibody

Western blot analysis of extracts of various cell lines, using GNB5 antibody at (MBS128782) 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit. (MBS128200)
Exposure time: 60s.
Rabbit Anti-GNB5 Polyclonal Antibody – Cat# MBS128782

Other Notes

Small volumes of anti-GNB5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GNB5 purchase

MBS128782 is an antibody targeting GNB5. Also known as GNB5 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GNB5. It may not necessarily be applicable to this product.

NCBI GI #
38258891
NCBI GeneID
10681
NCBI Accession #
O14775.2
UniProt Primary Accession #
O14775
UniProt Secondary Accession #
Q9HAU9; Q9UFT3; B2RBR5
UniProt Related Accession #
O14775
NCBI Official Full Name
Guanine nucleotide-binding protein subunit beta-5
NCBI Official Synonym Full Names
guanine nucleotide binding protein (G protein), beta 5
NCBI Official Symbol
GNB5
NCBI Official Synonym Symbols
GB5
UniProt Protein Name
Guanine nucleotide-binding protein subunit beta-5
UniProt Synonym Protein Names
Gbeta5; Transducin beta chain 5
Protein Family
Guanine nucleotide-binding protein
UniProt Gene Name
GNB5
UniProt Entry Name
GBB5_HUMAN
NCBI Protein Information
guanine nucleotide-binding protein subunit beta-5; gbeta5; transducin beta chain 5; G protein, beta-5 subunit; G protein, beta subunit 5L; guanine nucleotide-binding protein, beta subunit 5L

UniProt Comments for GNB5

G-beta 5: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the WD repeat G protein beta family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein, heterotrimeric beta

Chromosomal Location of Human Ortholog: 15q21.2

Cellular Component: plasma membrane; nucleus

Molecular Function: GTPase activity; G-protein gamma-subunit binding; signal transducer activity; protein binding; chaperone binding

Biological Process: rhodopsin mediated signaling; phototransduction, visible light; regulation of rhodopsin mediated signaling; metabolic process; signal transduction
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Research Articles on GNB5

1. Type 5 G protein beta subunit (Gbeta5) controls the interaction of regulator of G protein signaling 9 (RGS9) with membrane anchors

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GNB5 antibody

 Reference Product  PubMed Publications
 RGS7 antibody  >32 publications with GNB5 and RGS7
 RGS6 antibody  >12 publications with GNB5 and RGS6
 RGS11 antibody  >9 publications with GNB5 and RGS11
 PLCB2 antibody  >2 publications with GNB5 and PLCB2
 GNG2 antibody  >2 publications with GNB5 and GNG2
 RGS9BP antibody  >1 publications with GNB5 and RGS9BP

Pathways associated with anti-GNB5 antibody

 Products by Pathway  Pathway Diagram
 ADP Signalling Through P2Y Purinoceptor 1 Pathway antibodies  ADP Signalling Through P2Y Purinoceptor 1 Pathway Diagram
 ADP Signalling Through P2Y Purinoceptor 12 Pathway antibodies  ADP Signalling Through P2Y Purinoceptor 12 Pathway Diagram
 Activation Of Kainate Receptors Upon Glutamate Binding Pathway antibodies  Activation Of Kainate Receptors Upon Glutamate Binding Pathway Diagram
 Adrenaline,noradrenaline Inhibits Insulin Secretion Pathway antibodies  Adrenaline,noradrenaline Inhibits Insulin Secretion Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Aquaporin-mediated Transport Pathway antibodies  Aquaporin-mediated Transport Pathway Diagram
 Ca2+ Pathway antibodies  Ca2+ Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram

Diseases associated with anti-GNB5 antibody

 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >9 publications with GNB5 and Brain Diseases
 Kidney Diseases Antibodies  >5 publications with GNB5 and Kidney Diseases
 Nervous System Diseases Antibodies  >3 publications with GNB5 and Nervous System Diseases
 Hepatitis Antibodies  >1 publications with GNB5 and Hepatitis
 Hypertension Antibodies  >1 publications with GNB5 and Hypertension
 Neurobehavioral Manifestations Antibodies  >1 publications with GNB5 and Neurobehavioral Manifestations
 Liver Diseases Antibodies  >1 publications with GNB5 and Liver Diseases
 Learning Disorders Antibodies  >1 publications with GNB5 and Learning Disorders
 Necrosis Antibodies  >1 publications with GNB5 and Necrosis

Organs/Tissues associated with anti-GNB5 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >33 publications with GNB5 and Brain
 Eye Antibodies  >17 publications with GNB5 and Eye
 Kidney Antibodies  >9 publications with GNB5 and Kidney
 Nerve Antibodies  >6 publications with GNB5 and Nerve
 Pituitary Gland Antibodies  >2 publications with GNB5 and Pituitary Gland
 Ganglia Antibodies  >2 publications with GNB5 and Ganglia
 Spleen Antibodies  >1 publications with GNB5 and Spleen
 Liver Antibodies  >1 publications with GNB5 and Liver
 Muscle Antibodies  >1 publications with GNB5 and Muscle
 Embryonic Tissue Antibodies  >1 publications with GNB5 and Embryonic Tissue
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