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Serine Racemase (SRR) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1288880

Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine. More details

$385 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Serine racemase (SRR), Recombinant Protein
Full Product Name
Recombinant Human Serine racemase
Product Gene Name
SRR recombinant protein
Product Synonym Names
D-serine ammonia-lyase; D-serine dehydratase; L-serine ammonia-lyase; L-serine dehydratase
Sequence
MCAQYCISFA DVEKAHINIR DSIHLTPVLT SSILNQLTGR NLFFKCELFQ KTGSFKIRGA LNAVRSLVPD ALERKPKAVV THSSGNHGQA LTYAAKLEGI PAYIVVPQTA PDCKKLAIQA YGASIVYCEP SDESRENVAK RVTEETEGIM VHPNQEPAVI AGQGTIALEV LNQVPLVDAL VVPVGGGGML AGIAITVKAL KPSVKVYAAE PSNADDCYQS KLKGKLMPNL YPPETIADGV KSSIGLNTWP IIRDLVDDIF TVTEDEIKCA TQLVWERMKL LIEPTAGVGV AAVLSQHFQT VSPEVKNICI VLSGGNVDLT SSITWVKQAE RPASYQSVSV
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Molecular Weight
52.6 kDa
Sequence Positions
1-340aa; Full Length
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
606477
3D Structure
ModBase 3D Structure for Q9GZT4
Species
Homo sapiens (Human)

Product Categories/Family for SRR recombinant protein

Neuroscience
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

SDS-PAGE of SRR recombinant protein

Human SRR Recombinant Protein – Cat# MBS1288880

Product References and Citations for SRR recombinant protein

"Human serine racemase: molecular cloning, genomic organization and functional expression." De Miranda J., Santoro A., Engelender S., Wolosker H. Gene 256:183-188(2000)

Other Notes

Small volumes of SRR recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SRR purchase

MBS1288880 is a recombinant protein targeting SRR. Also known as Recombinant Human Serine racemase. Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for SRR. It may not necessarily be applicable to this product.

NCBI GI #
11345492
NCBI GeneID
63826
NCBI Accession #
NP_068766.1
UniProt Primary Accession #
Q9GZT4
UniProt Secondary Accession #
Q6IA55; D3DTI5
UniProt Related Accession #
Q9GZT4
GenBank Nucleotide #
NM_021947.2
NCBI Official Full Name
serine racemase isoform a
NCBI Official Synonym Full Names
serine racemase
NCBI Official Symbol
SRR
NCBI Official Synonym Symbols
ILV1; ISO1
UniProt Protein Name
Serine racemase
UniProt Synonym Protein Names
D-serine ammonia-lyase; D-serine dehydratase (EC:4.3.1.18
Protein Family
Probable serine racemase
UniProt Gene Name
SRR
UniProt Entry Name
SRR_HUMAN
NCBI Protein Information
serine racemase

UniProt Comments for SRR

SRR: Catalyzes the synthesis of D-serine from L-serine. D- serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine. Belongs to the serine/threonine dehydratase family.

Protein type: Amino Acid Metabolism - glycine, serine and threonine; Isomerase; EC 5.1.1.18; EC 4.3.1.17; EC 4.3.1.18

Chromosomal Location of Human Ortholog: 17p13

Cellular Component: apical part of cell; cell soma; cytoplasm; plasma membrane

Molecular Function: ATP binding; calcium ion binding; D-serine ammonia-lyase activity; glycine binding; L-serine ammonia-lyase activity; magnesium ion binding; PDZ domain binding; protein homodimerization activity; pyridoxal phosphate binding; serine racemase activity; threonine racemase activity

Biological Process: aging; brain development; L-serine metabolic process; protein homotetramerization; pyruvate biosynthetic process; response to drug; response to lipopolysaccharide; response to morphine; serine family amino acid metabolic process
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Research Articles on SRR

1. Serine racemase activity and dynamics are regulated by halides, ATP and malonate.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with SRR recombinant protein

 Reference Product  PubMed Publications
 SHMT1 recombinant protein  >3 publications with SRR and SHMT1
 UBC recombinant protein  >1 publications with SRR and UBC
 SDS recombinant protein  >1 publications with SRR and SDS

Pathways associated with SRR recombinant protein

 Products by Pathway  Pathway Diagram
 Glycine, Serine And Threonine Metabolism Pathway antibodies  Glycine, Serine And Threonine Metabolism Pathway Diagram
 Glycine, Serine And Threonine Metabolism Pathway antibodies  Glycine, Serine And Threonine Metabolism Pathway Diagram
 Serine And Glycine Biosynthesis Pathway antibodies  Serine And Glycine Biosynthesis Pathway Diagram

Diseases associated with SRR recombinant protein

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >45 publications with SRR and Cardiovascular Diseases
 Breast Neoplasms Antibodies  >26 publications with SRR and Breast Neoplasms
 Brain Diseases Antibodies  >22 publications with SRR and Brain Diseases
 Hypertension Antibodies  >18 publications with SRR and Hypertension
 Liver Diseases Antibodies  >16 publications with SRR and Liver Diseases
 Disease Models, Animal Antibodies  >14 publications with SRR and Disease Models, Animal
 Liver Neoplasms Antibodies  >14 publications with SRR and Liver Neoplasms
 Kidney Diseases Antibodies  >11 publications with SRR and Kidney Diseases
 Infertility, Male Antibodies  >10 publications with SRR and Infertility, Male
 Poisoning Antibodies  >6 publications with SRR and Poisoning

Organs/Tissues associated with SRR recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >93 publications with SRR and Blood
 Brain Antibodies  >58 publications with SRR and Brain
 Liver Antibodies  >44 publications with SRR and Liver
 Lung Antibodies  >42 publications with SRR and Lung
 Heart Antibodies  >41 publications with SRR and Heart
 Kidney Antibodies  >37 publications with SRR and Kidney
 Bone Antibodies  >37 publications with SRR and Bone
 Vascular Antibodies  >15 publications with SRR and Vascular
 Muscle Antibodies  >15 publications with SRR and Muscle
 Prostate Antibodies  >14 publications with SRR and Prostate
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