Rabbit Anti-PDIA6 Polyclonal Antibody – Cat# MBS128905

Western blot analysis of extracts of various cell lines, using PDIA6 antibody.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.

PDIA6 Antibody – Rabbit Polyclonal

Name: PDIA6 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS128905
Price: 360 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS128905

Protein disulfide isomerases (EC 5.3.4.1), such as PDIA6, are endoplasmic reticulum (ER) resident proteins that catalyze formation, reduction, and isomerization of disulfide bonds in proteins and are thought to play a role in folding of disulfide-bonded… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

PDIA6, Polyclonal Antibody

Full Product Name

PDIA6 Polyclonal Antibody

Product Gene Name

anti-PDIA6 antibody

Product Synonym Names

P5; ERP5; TXNDC7

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Purity/Purification

Affinity Purification

Concentration

1mg/ml (lot specific)

Preparation and Storage

Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

440

OMIM

611099

3D Structure

ModBase 3D Structure for Q15084

Species

Human

Immunogen

Recombinant protein of human PDIA6

Calculated Molecular Weight

48kDa

Product Categories/Family for anti-PDIA6 antibody

Polyclonal

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-PDIA6 antibody

Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-PDIA6 antibody

WB: 1:1000 - 1:2000
IHC: 1:50 - 1:200

Other Notes

Small volumes of anti-PDIA6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PDIA6 purchase

MBS128905 is an antibody targeting PDIA6. Also known as PDIA6 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PDIA6. It may not necessarily be applicable to this product.

NCBI GI #

2501205

NCBI GeneID

10130

NCBI Accession #

Q15084.1

UniProt Primary Accession #

Q15084

UniProt Secondary Accession #

Q53RC7; Q6ZSH5; Q99778; B3KY95; B5MCQ5; B7Z254; B7Z4M8; F8WA83

UniProt Related Accession #

Q15084

NCBI Official Full Name

Protein disulfide-isomerase A6

NCBI Official Synonym Full Names

protein disulfide isomerase family A, member 6

NCBI Official Symbol

PDIA6

NCBI Official Synonym Symbols

P5; ERP5; TXNDC7

UniProt Protein Name

Protein disulfide-isomerase A6

UniProt Synonym Protein Names

Endoplasmic reticulum protein 5; ER protein 5; ERp5; Protein disulfide isomerase P5; Thioredoxin domain-containing protein 7

Protein Family

Protein disulfide-isomerase

UniProt Gene Name

PDIA6

UniProt Synonym Gene Names

ERP5; P5; TXNDC7; ER protein 5; ERp5

UniProt Entry Name

PDIA6_HUMAN

NCBI Protein Information

protein disulfide-isomerase A6; ER protein 5; protein disulfide isomerase P5; endoplasmic reticulum protein 5; thioredoxin domain-containing protein 7; protein disulfide isomerase-associated 6; protein disulfide isomerase-related protein; thioredoxin domain containing 7 (protein disulfide isomerase)

NCBI Summary for PDIA6

UniProt Comments for PDIA6

PDIA6: May function as a chaperone that inhibits aggregation of misfolded proteins. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin. Belongs to the protein disulfide isomerase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 5.3.4.1; Isomerase

Chromosomal Location of Human Ortholog: 2p25.1

Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum lumen; endoplasmic reticulum; melanosome; plasma membrane; ER-Golgi intermediate compartment

Molecular Function: protein binding; protein disulfide isomerase activity

Biological Process: unfolded protein response, activation of signaling protein activity; cellular protein metabolic process; protein folding; unfolded protein response; cell redox homeostasis; apoptotic cell clearance

Research Articles on PDIA6

1. levels of expression of ERp5 and GRP78 correlated with the level of expression of membrane-bound MICA in chronic lymphocytic leukemia patients.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PDIA6 antibody

Reference Product	PubMed Publications
PDIA4 antibody	>5 publications with PDIA6 and PDIA4
HSPA5 antibody	>3 publications with PDIA6 and HSPA5
HSP90B1 antibody	>2 publications with PDIA6 and HSP90B1

Pathways associated with anti-PDIA6 antibody

Products by Pathway	Pathway Diagram
IRE1alpha Activates Chaperones Pathway antibodies	IRE1alpha Activates Chaperones Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Protein Processing In Endoplasmic Reticulum Pathway antibodies	Protein Processing In Endoplasmic Reticulum Pathway Diagram
Protein Processing In Endoplasmic Reticulum Pathway antibodies	Protein Processing In Endoplasmic Reticulum Pathway Diagram
Unfolded Protein Response (UPR) Pathway antibodies	Unfolded Protein Response (UPR) Pathway Diagram
XBP1(S) Activates Chaperone Genes Pathway antibodies	XBP1(S) Activates Chaperone Genes Pathway Diagram

Diseases associated with anti-PDIA6 antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>3 publications with PDIA6 and Nervous System Diseases
Liver Diseases Antibodies	>2 publications with PDIA6 and Liver Diseases
Kidney Diseases Antibodies	>2 publications with PDIA6 and Kidney Diseases
Inflammation Antibodies	>2 publications with PDIA6 and Inflammation
Anoxia Antibodies	>1 publications with PDIA6 and Anoxia
Hepatitis Antibodies	>1 publications with PDIA6 and Hepatitis
Brain Diseases Antibodies	>1 publications with PDIA6 and Brain Diseases
Cardiovascular Diseases Antibodies	>1 publications with PDIA6 and Cardiovascular Diseases
Carcinoma, Hepatocellular Antibodies	>1 publications with PDIA6 and Carcinoma, Hepatocellular
Disease Models, Animal Antibodies	>1 publications with PDIA6 and Disease Models, Animal

Organs/Tissues associated with anti-PDIA6 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>6 publications with PDIA6 and Blood
Brain Antibodies	>4 publications with PDIA6 and Brain
Lung Antibodies	>3 publications with PDIA6 and Lung
Liver Antibodies	>3 publications with PDIA6 and Liver
Vascular Antibodies	>2 publications with PDIA6 and Vascular
Kidney Antibodies	>2 publications with PDIA6 and Kidney
Pancreas Antibodies	>2 publications with PDIA6 and Pancreas
Muscle Antibodies	>2 publications with PDIA6 and Muscle
Bone Marrow Antibodies	>2 publications with PDIA6 and Bone Marrow
Heart Antibodies	>2 publications with PDIA6 and Heart