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IVNS1ABP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS128945
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MBS128945 is an antibody targeting IVNS1ABP. Also known as IVNS1ABP Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
IVNS1ABP, Polyclonal Antibody
Full Product Name
IVNS1ABP Polyclonal Antibody
Product Gene Name
Product Synonym Names
ND1; NS-1; NS1BP; FLARA3; KLHL39; NS1-BP; HSPC068
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
642
OMIM
609209
3D Structure
ModBase 3D Structure for Q9Y6Y0
Species
Human
Immunogen
Recombinant protein of human IVNS1ABP
Calculated Molecular Weight
72kDa

Product Categories/Family for anti-IVNS1ABP antibody

ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-IVNS1ABP antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-IVNS1ABP antibody
WB: 1:500-1:2000
IHC: 1:50-1:200

Western Blot (WB) of anti-IVNS1ABP antibody

Western blot analysis of extracts of various cell lines, using IVNS1ABP antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 30s.
Rabbit Anti-IVNS1ABP Polyclonal Antibody – Cat# MBS128945

Immunohistochemistry (IHC) of anti-IVNS1ABP antibody

Immunohistochemistry of paraffin-embedded rat brain using IVNS1ABP antibody at dilution of 1:100 (40x lens).
Rabbit Anti-IVNS1ABP Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS128945

Immunohistochemistry (IHC) of anti-IVNS1ABP antibody

Immunohistochemistry of paraffin-embedded rat pancreas using IVNS1ABP antibody at dilution of 1:100 (40x lens).
Rabbit Anti-IVNS1ABP Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS128945

Immunohistochemistry (IHC) of anti-IVNS1ABP antibody

Immunohistochemistry of paraffin-embedded human tonsil using IVNS1ABP antibody at dilution of 1:100 (40x lens).
Rabbit Anti-IVNS1ABP Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS128945

Other Notes

Small volumes of anti-IVNS1ABP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IVNS1ABP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Influenza virus NS1A-binding protein
NCBI Official Synonym Full Names
influenza virus NS1A binding protein
NCBI Official Symbol
IVNS1ABP
NCBI Official Synonym Symbols
ND1; NS-1; NS1BP; FLARA3; KLHL39; NS1-BP; HSPC068
UniProt Protein Name
Influenza virus NS1A-binding protein
UniProt Synonym Protein Names
Aryl hydrocarbon receptor-associated protein 3
UniProt Gene Name
IVNS1ABP
UniProt Synonym Gene Names
ARA3; FLARA3; KIAA0850; NS1; NS1BP; NS1-BP; NS1-binding protein
UniProt Entry Name
NS1BP_HUMAN
NCBI Protein Information
influenza virus NS1A-binding protein; NS1-binding protein; NCX downstream gene 1; kelch-like family member 39; aryl hydrocarbon receptor-associated 3; aryl hydrocarbon receptor-associated protein 3

UniProt Comments for IVNS1ABP

IVNS1ABP: Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines. May be a component of the cellular splicing machinery with a role in pre-mRNA splicing; may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription.

Chromosomal Location of Human Ortholog: 1q25.1-q31.1

Cellular Component: nucleoplasm; spliceosome; transcription factor complex; cytoplasm; actin cytoskeleton

Biological Process: transcription from RNA polymerase III promoter; viral reproduction; response to virus; RNA splicing
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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