Rabbit Anti-MOV10 Polyclonal Antibody – Cat# MBS128988

Western blot analysis of extracts of various cell lines, using MOV10 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 30s.

MOV10 Antibody – Rabbit Polyclonal

Name: MOV10 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS128988
Price: 225 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS128988

MBS128988 is an antibody targeting MOV10. Also known as MOV10 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

MOV10, Polyclonal Antibody

Full Product Name

MOV10 Polyclonal Antibody

Product Gene Name

anti-MOV10 antibody

Product Synonym Names

gb110; fSAP113

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Purity/Purification

Affinity Purification

Concentration

1mg/ml (lot specific)

Preparation and Storage

Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

1003

OMIM

610742

3D Structure

ModBase 3D Structure for Q9HCE1

Species

Human

Immunogen

Recombinant protein of human MOV10

Calculated Molecular Weight

114kDa

Product Categories/Family for anti-MOV10 antibody

Polyclonal

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-MOV10 antibody

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Application Notes for anti-MOV10 antibody

WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:20 - 1:100
IP: 1:20 - 1:50

Other Notes

Small volumes of anti-MOV10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MOV10. It may not necessarily be applicable to this product.

NCBI GI #

24638063

NCBI GeneID

4343

NCBI Accession #

Q9HCE1.2

UniProt Primary Accession #

Q9HCE1

UniProt Secondary Accession #

Q5JR03; Q8TEF0; Q9BSY3; Q9BUJ9

UniProt Related Accession #

Q9HCE1

NCBI Official Full Name

Putative helicase MOV-10

NCBI Official Synonym Full Names

Mov10 RISC complex RNA helicase

NCBI Official Symbol

MOV10

NCBI Official Synonym Symbols

gb110; fSAP113

UniProt Protein Name

Putative helicase MOV-10

UniProt Synonym Protein Names

Moloney leukemia virus 10 protein

Protein Family

Putative helicase

UniProt Gene Name

MOV10

UniProt Synonym Gene Names

KIAA1631

UniProt Entry Name

MOV10_HUMAN

NCBI Protein Information

putative helicase MOV-10; moloney leukemia virus 10 protein; Mov10, Moloney leukemia virus 10, homolog; functional spliceosome-associated protein 113

UniProt Comments for MOV10

MOV10: Probable RNA helicase. Required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA- mediated cleavage of complementary mRNAs by RISC. Also required for RNA-directed transcription and replication of the human hepatitis delta virus (HDV). Interacts with small capped HDV RNAs derived from genomic hairpin structures that mark the initiation sites of RNA-dependent HDV RNA transcription. Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; RNA processing; Helicase; EC 3.6.4.13; Spliceosome

Chromosomal Location of Human Ortholog: 1p13.2

Cellular Component: extracellular space; cytosol

Molecular Function: protein binding; helicase activity; ATP binding

Biological Process: epidermal growth factor receptor signaling pathway; Notch signaling pathway; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; transcription, DNA-dependent; regulation of transcription, DNA-dependent; nerve growth factor receptor signaling pathway; miRNA-mediated gene silencing, mRNA cleavage; innate immune response

Research Articles on MOV10

1. Results show that MOV10 predominantly binds to 3' UTRs upstream of regions predicted to form local secondary structures and provide evidence that MOV10 helicase mutants are impaired in their ability to translocate 5' to 3' on their mRNA targets.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MOV10 antibody

Reference Product	PubMed Publications
TNRC6B antibody	>3 publications with MOV10 and TNRC6B
EIF6 antibody	>1 publications with MOV10 and EIF6
EIF2C1 antibody	>1 publications with MOV10 and EIF2C1
CBX7 antibody	>1 publications with MOV10 and CBX7

Pathways associated with anti-MOV10 antibody

Products by Pathway	Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Ca2+ Pathway antibodies	Ca2+ Pathway Diagram
Cellular Senescence Pathway antibodies	Cellular Senescence Pathway Diagram
Cellular Responses To Stress Pathway antibodies	Cellular Responses To Stress Pathway Diagram
DAP12 Interactions Pathway antibodies	DAP12 Interactions Pathway Diagram
DAP12 Signaling Pathway antibodies	DAP12 Signaling Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Downstream Signal Transduction Pathway antibodies	Downstream Signal Transduction Pathway Diagram
Downstream Signaling Events Of B Cell Receptor (BCR) Pathway antibodies	Downstream Signaling Events Of B Cell Receptor (BCR) Pathway Diagram
Downstream Signaling Of Activated FGFR Pathway antibodies	Downstream Signaling Of Activated FGFR Pathway Diagram

Diseases associated with anti-MOV10 antibody

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>2 publications with MOV10 and Cardiovascular Diseases
Heart Diseases Antibodies	>1 publications with MOV10 and Heart Diseases

Organs/Tissues associated with anti-MOV10 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>4 publications with MOV10 and Brain
Testis Antibodies	>4 publications with MOV10 and Testis
Heart Antibodies	>3 publications with MOV10 and Heart
Blood Antibodies	>3 publications with MOV10 and Blood
Ovary Antibodies	>1 publications with MOV10 and Ovary
Muscle Antibodies	>1 publications with MOV10 and Muscle
Embryonic Tissue Antibodies	>1 publications with MOV10 and Embryonic Tissue