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HSPB8 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS129059
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The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive… More details

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Product Overview

Online Datasheet in PDF
Product Name
HSPB8, Polyclonal Antibody
Full Product Name
HSPB8 Polyclonal Antibody
Product Gene Name
anti-HSPB8 antibody
Product Synonym Names
H11; HMN2; CMT2L; DHMN2; E2IG1; HMN2A; HSP22
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
196
OMIM
gene 608673
3D Structure
ModBase 3D Structure for Q9UJY1
Species
Human
Immunogen
Recombinant protein of human HSPB8
Calculated Molecular Weight
22kDa

Product Categories/Family for anti-HSPB8 antibody

Polyclonal
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-HSPB8 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-HSPB8 antibody
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:100

Western Blot (WB) of anti-HSPB8 antibody

Western blot analysis of extracts of various cell lines, using HSPB8 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 10s.
Rabbit Anti-HSPB8 Polyclonal Antibody – Cat# MBS129059

Immunohistochemistry (IHC) of anti-HSPB8 antibody

Immunohistochemistry of paraffin-embedded rat lung using HSPB8 antibody at dilution of 1:200 (40x lens).
Rabbit Anti-HSPB8 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS129059

Immunohistochemistry (IHC) of anti-HSPB8 antibody

Immunohistochemistry of paraffin-embedded rat pancreas using HSPB8 antibody at dilution of 1:200 (40x lens).
Rabbit Anti-HSPB8 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS129059

Immunohistochemistry (IHC) of anti-HSPB8 antibody

Immunohistochemistry of paraffin-embedded human thyroid cancer using HSPB8 antibody at dilution of 1:200 (40x lens).
Rabbit Anti-HSPB8 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS129059

Immunohistochemistry (IHC) of anti-HSPB8 antibody

Immunohistochemistry of paraffin-embedded human normal colon using HSPB8 antibody at dilution of 1:200 (40x lens).
Rabbit Anti-HSPB8 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS129059

Immunohistochemistry (IHC) of anti-HSPB8 antibody

Immunohistochemistry of paraffin-embedded human colon cancer using HSPB8 antibody at dilution of 1:200 (40x lens).
Rabbit Anti-HSPB8 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS129059

Immunohistochemistry (IHC) of anti-HSPB8 antibody

Immunohistochemistry of paraffin-embedded human lung cancer using HSPB8 antibody at dilution of 1:200 (40x lens).
Rabbit Anti-HSPB8 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS129059

Immunohistochemistry (IHC) of anti-HSPB8 antibody

Immunohistochemistry of paraffin-embedded human stomach cancer using HSPB8 antibody at dilution of 1:200 (40x lens).
Rabbit Anti-HSPB8 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS129059

Immunofluorescence (IF) of anti-HSPB8 antibody

Immunofluorescence analysis of HeLa cells using HSPB8 antibody. Blue: DAPI for nuclear staining.
Rabbit Anti-HSPB8 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS129059

Other Notes

Small volumes of anti-HSPB8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HSPB8 purchase

MBS129059 is an antibody targeting HSPB8. Also known as HSPB8 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HSPB8. It may not necessarily be applicable to this product.

NCBI GI #
13431576
NCBI GeneID
26353
NCBI Accession #
Q9UJY1.1
UniProt Primary Accession #
Q9UJY1
UniProt Secondary Accession #
Q6FIH3; Q9UKS3; B2R6A6
UniProt Related Accession #
Q9UJY1
NCBI Official Full Name
Heat shock protein beta-8
NCBI Official Synonym Full Names
heat shock 22kDa protein 8
NCBI Official Symbol
HSPB8
NCBI Official Synonym Symbols
H11; HMN2; CMT2L; DHMN2; E2IG1; HMN2A; HSP22
UniProt Protein Name
Heat shock protein beta-8
UniProt Synonym Protein Names
Alpha-crystallin C chain; E2-induced gene 1 protein; Protein kinase H11; Small stress protein-like protein HSP22
Protein Family
Heat shock protein
UniProt Gene Name
HSPB8
UniProt Synonym Gene Names
CRYAC; E2IG1; HSP22; HspB8
UniProt Entry Name
HSPB8_HUMAN
NCBI Protein Information
heat shock protein beta-8; protein kinase H11; alpha-crystallin C chain; E2-induced gene 1 protein; heat shock 27kDa protein 8; small stress protein-like protein HSP22

UniProt Comments for HSPB8

HSPB8: Displays temperature-dependent chaperone activity. Monomer. Interacts with HSPB1. Interacts with DNAJB6. By 17-beta-estradiol. Predominantly expressed in skeletal muscle and heart. Belongs to the small heat shock protein (HSP20) family.

Protein type: Heat shock protein

Chromosomal Location of Human Ortholog: 12q24.23

Cellular Component: nucleoplasm; Golgi apparatus; cytoplasm; intracellular; nucleus

Molecular Function: identical protein binding; protein binding; protein kinase activity

Disease: Charcot-marie-tooth Disease, Axonal, Type 2l; Neuronopathy, Distal Hereditary Motor, Type Iia
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Research Articles on HSPB8

1. HSP22 plays an important role on gastric tumor aggressiveness and prognosis and may act as a promising target for prognostic prediction.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-HSPB8 antibody

 Reference Product  PubMed Publications
 HSPB1 antibody  >56 publications with HSPB8 and HSPB1
 BAG3 antibody  >17 publications with HSPB8 and BAG3
 HSPB2 antibody  >12 publications with HSPB8 and HSPB2
 HSPB3 antibody  >10 publications with HSPB8 and HSPB3
 HSPB7 antibody  >7 publications with HSPB8 and HSPB7
 TRPV4 antibody  >5 publications with HSPB8 and TRPV4
 MPZ antibody  >5 publications with HSPB8 and MPZ
 CRYAB antibody  >5 publications with HSPB8 and CRYAB

Diseases associated with anti-HSPB8 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >50 publications with HSPB8 and Nervous System Diseases
 Congenital Abnormalities Antibodies  >25 publications with HSPB8 and Congenital Abnormalities
 Cardiovascular Diseases Antibodies  >18 publications with HSPB8 and Cardiovascular Diseases
 Heart Diseases Antibodies  >15 publications with HSPB8 and Heart Diseases
 Brain Diseases Antibodies  >11 publications with HSPB8 and Brain Diseases
 Hypertrophy Antibodies  >10 publications with HSPB8 and Hypertrophy
 Disease Models, Animal Antibodies  >7 publications with HSPB8 and Disease Models, Animal
 Breast Neoplasms Antibodies  >7 publications with HSPB8 and Breast Neoplasms
 Inflammation Antibodies  >5 publications with HSPB8 and Inflammation
 Neoplasms, Experimental Antibodies  >4 publications with HSPB8 and Neoplasms, Experimental

Organs/Tissues associated with anti-HSPB8 antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >48 publications with HSPB8 and Muscle
 Heart Antibodies  >24 publications with HSPB8 and Heart
 Brain Antibodies  >22 publications with HSPB8 and Brain
 Nerve Antibodies  >20 publications with HSPB8 and Nerve
 Kidney Antibodies  >5 publications with HSPB8 and Kidney
 Skin Antibodies  >5 publications with HSPB8 and Skin
 Prostate Antibodies  >4 publications with HSPB8 and Prostate
 Vascular Antibodies  >3 publications with HSPB8 and Vascular
 Spinal Cord Antibodies  >3 publications with HSPB8 and Spinal Cord
 Bone Antibodies  >3 publications with HSPB8 and Bone
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