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Serine/Threonine-Protein Phosphatase 2a 56 Kda Regulatory Subunit Delta Isoform (PPP2R5D) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1292088

MBS1292088 is a recombinant protein targeting PPP2R5D. Also known as Recombinant Human Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PPP2R5D). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1400 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PPP2R5D), Recombinant Protein
Full Product Name
Recombinant Human Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PPP2R5D)
Product Gene Name
PPP2R5D recombinant protein
Product Synonym Gene Name
PPP2R5D
Sequence
MPYKLKKEKE PPKVAKCTAK PSSSGKDGGG ENTEEAQPQP QPQPQPQAQS QPPSSNKRPS NSTPPPTQLS KIKYSGGPQI VKKERRQSSS RFNLSKNREL QKLPALKDSP TQEREELFIQ KLRQCCVLFD FVSDPLSDLK FKEVKRAGLN EMVEYITHSR DVVTEAIYPE AVTMFSVNLF RTLPPSSNPT GAEFDPEEDE PTLEAAWPHL QLVYEFFLRF LESPDFQPNI AKKYIDQKFV LALLDLFDSE DPRERDFLKT ILHRIYGKFL GLRAYIRRQI NHIFYRFIYE TEHHNGIAEL LEILGSIING FALPLKEEHK MFLIRVLLPL HKVKSLSVYH PQLAYCVVQF LEKESSLTEP VIVGLLKFWP KTHSPKEVMF LNELEEILDV IEPSEFSKVM EPLFRQLAKC VSSPHFQVAE RALYYWNNEY IMSLISDNAA RVLPIMFPAL YRNSKSHWNK TIHGLIYNAL KLFMEMNQKL FDDCTQQYKA EKQKGRFRMK EREEMWQKIE ELARLNPQYP MFRAPPPLPP VYSMETETPT AEDIQLLKRT VETEAVQMLK DIKKEKVLLR RKSELPQDVY TIKALEAHKR AEEFLTASQE AL
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
58,453 Da
Sequence Positions
1-602, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
601646
3D Structure
ModBase 3D Structure for Q14738
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PPP2R5D recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PPP2R5D. It may not necessarily be applicable to this product.

NCBI GI #
394582140
NCBI GeneID
5528
NCBI Accession #
NP_001257405.1
UniProt Primary Accession #
Q14738
UniProt Secondary Accession #
O00494; O00696; Q15171; Q5TC39; A8K3I9; B5BUA6
UniProt Related Accession #
Q14738
GenBank Nucleotide #
NM_001270476.1
NCBI Official Full Name
serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform isoform 4
NCBI Official Synonym Full Names
protein phosphatase 2 regulatory subunit B'delta
NCBI Official Symbol
PPP2R5D
NCBI Official Synonym Symbols
B56D; MRD35; B56delta
UniProt Protein Name
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform
UniProt Synonym Protein Names
PP2A B subunit isoform B'-delta; PP2A B subunit isoform B56-delta; PP2A B subunit isoform PR61-delta; PP2A B subunit isoform R5-delta
Protein Family
Serine/threonine-protein phosphatase
UniProt Gene Name
PPP2R5D
NCBI Protein Information
serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

NCBI Summary for PPP2R5D

The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
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UniProt Comments for PPP2R5D

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

Research Articles on PPP2R5D

1. Mutations in PPP2R5D are genetic cause of intellectual disability.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PPP2R5D recombinant protein

 Reference Product  PubMed Publications
 HAND1 recombinant protein  >1 publications with PPP2R5D and HAND1

Pathways associated with PPP2R5D recombinant protein

 Products by Pathway  Pathway Diagram
 Activated TLR4 Signalling Pathway antibodies  Activated TLR4 Signalling Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Alpha-synuclein Signaling Pathway antibodies  Alpha-synuclein Signaling Pathway Diagram
 Aurora A Signaling Pathway antibodies  Aurora A Signaling Pathway Diagram
 Aurora B Signaling Pathway antibodies  Aurora B Signaling Pathway Diagram
 Beta-catenin Phosphorylation Cascade Pathway antibodies  Beta-catenin Phosphorylation Cascade Pathway Diagram
 CTLA4 Inhibitory Signaling Pathway antibodies  CTLA4 Inhibitory Signaling Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Costimulation By The CD28 Family Pathway antibodies  Costimulation By The CD28 Family Pathway Diagram

Diseases associated with PPP2R5D recombinant protein

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >2 publications with PPP2R5D and Nervous System Diseases

Organs/Tissues associated with PPP2R5D recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with PPP2R5D and Brain
 Testis Antibodies  >3 publications with PPP2R5D and Testis
 Thyroid Antibodies  >2 publications with PPP2R5D and Thyroid
 Kidney Antibodies  >2 publications with PPP2R5D and Kidney
 Adipose Tissue Antibodies  >1 publications with PPP2R5D and Adipose Tissue
 Placenta Antibodies  >1 publications with PPP2R5D and Placenta
 Connective Tissue Antibodies  >1 publications with PPP2R5D and Connective Tissue
 Liver Antibodies  >1 publications with PPP2R5D and Liver
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