Rabbit Anti-STX4 Polyclonal Antibody – Cat# MBS129231

Western blot analysis of extracts of various cell lines, using STX4 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 15s.

STX4 Antibody – Rabbit Polyclonal

Name: STX4 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS129231
Price: 225 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS129231

MBS129231 is an antibody targeting STX4. Also known as STX4 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$225 / 0.02 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

STX4, Polyclonal Antibody

Full Product Name

STX4 Polyclonal Antibody

Product Gene Name

anti-STX4 antibody

Product Synonym Names

STX4A; p35-2

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Purity/Purification

Affinity Purification

Concentration

1mg/ml (lot specific)

Preparation and Storage

Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

297

OMIM

186591

3D Structure

ModBase 3D Structure for Q12846

Species

Human

Immunogen

Recombinant protein of human STX4

Calculated Molecular Weight

34kDa

Product Categories/Family for anti-STX4 antibody

Polyclonal

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-STX4 antibody

Western Blot (WB)

Application Notes for anti-STX4 antibody

WB: 1:500-1:2000

Other Notes

Small volumes of anti-STX4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for STX4. It may not necessarily be applicable to this product.

NCBI GI #

3041737

NCBI GeneID

6810

NCBI Accession #

Q12846.2

UniProt Primary Accession #

Q12846

UniProt Secondary Accession #

Q15525; Q6FHE8; A8MXY0

UniProt Related Accession #

Q12846

NCBI Official Full Name

Syntaxin-4

NCBI Official Synonym Full Names

syntaxin 4

NCBI Official Symbol

STX4

NCBI Official Synonym Symbols

STX4A; p35-2

UniProt Protein Name

Syntaxin-4

UniProt Synonym Protein Names

Renal carcinoma antigen NY-REN-31

Protein Family

Syntaxin-binding protein

UniProt Gene Name

STX4

UniProt Synonym Gene Names

STX4A

UniProt Entry Name

STX4_HUMAN

NCBI Protein Information

syntaxin-4; syntaxin 4A (placental); renal carcinoma antigen NY-REN-31

UniProt Comments for STX4

STX4: a protein of the syntaxin/epimorphin family. Contains 1 t-SNARE coiled-coil homology domain. Potentially involved in docking of synaptic vesicles at presynaptic active zones. Interacts with SNAP23 and SNAP25BP. Found in a complex with VAMP8 and SNAP23 in pancreas.

Protein type: Vesicle; Membrane protein, integral

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: extracellular space; specific granule; cell surface; lateral loop; basolateral plasma membrane; integral to membrane; dendritic spine; trans-Golgi network; cytosol; SNARE complex; synaptic vesicle; membrane; perinuclear region of cytoplasm; lamellipodium; plasma membrane; vacuole; synapse; intracellular; endosome

Molecular Function: sphingomyelin phosphodiesterase activator activity; SNAP receptor activity; SNARE binding; protein binding

Biological Process: positive regulation of catalytic activity; platelet activation; positive regulation of cell adhesion; organelle fusion; positive regulation of eosinophil degranulation; positive regulation of chemotaxis; positive regulation of immunoglobulin secretion; synaptic vesicle fusion to presynaptic membrane; regulation of exocytosis; intracellular protein transport; response to hydroperoxide; vesicle docking; positive regulation of cell proliferation; post-Golgi vesicle-mediated transport; blood coagulation; positive regulation of cell migration

Research Articles on STX4

1. upregulation of Syntaxin 4 is sufficient to significantly improve insulin secretory function to human type 2 diabetes islets retaining low levels of residual function

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-STX4 antibody

Reference Product	PubMed Publications
VAMP3 antibody	>5 publications with STX4 and VAMP3
SNAP23 antibody	>5 publications with STX4 and SNAP23
STXBP4 antibody	>2 publications with STX4 and STXBP4
VAMP2 antibody	>2 publications with STX4 and VAMP2
VAMP4 antibody	>1 publications with STX4 and VAMP4
VAMP8 antibody	>1 publications with STX4 and VAMP8
STXBP3 antibody	>1 publications with STX4 and STXBP3

Pathways associated with anti-STX4 antibody

Products by Pathway	Pathway Diagram
Clathrin Derived Vesicle Budding Pathway antibodies	Clathrin Derived Vesicle Budding Pathway Diagram
Disinhibition Of SNARE Formation Pathway antibodies	Disinhibition Of SNARE Formation Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Insulin Signaling Pathway antibodies	Insulin Signaling Pathway Diagram
Insulin-mediated Glucose Transport Pathway antibodies	Insulin-mediated Glucose Transport Pathway Diagram
Membrane Trafficking Pathway antibodies	Membrane Trafficking Pathway Diagram
Platelet Activation, Signaling And Aggregation Pathway antibodies	Platelet Activation, Signaling And Aggregation Pathway Diagram
Response To Elevated Platelet Cytosolic Ca2+ Pathway antibodies	Response To Elevated Platelet Cytosolic Ca2+ Pathway Diagram
SNARE Interactions In Vesicular Transport Pathway antibodies	SNARE Interactions In Vesicular Transport Pathway Diagram
SNARE Interactions In Vesicular Transport Pathway antibodies	SNARE Interactions In Vesicular Transport Pathway Diagram

Diseases associated with anti-STX4 antibody

Disease Name	Pubmed Publications
Atherosclerosis Antibodies	>1 publications with STX4 and Atherosclerosis

Organs/Tissues associated with anti-STX4 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>2 publications with STX4 and Blood
Brain Antibodies	>2 publications with STX4 and Brain
Nerve Antibodies	>1 publications with STX4 and Nerve
Kidney Antibodies	>1 publications with STX4 and Kidney
Eye Antibodies	>1 publications with STX4 and Eye
Liver Antibodies	>1 publications with STX4 and Liver