Rabbit Anti-GGPS1 Polyclonal Antibody – Cat# MBS129240

Western blot analysis of extracts of Jurkat cells, using GGPS1 antibody.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.

GGPS1 Antibody – Rabbit Polyclonal

Name: GGPS1 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS129240
Price: 360 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS129240

This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

GGPS1, Polyclonal Antibody

Full Product Name

GGPS1 Polyclonal Antibody

Product Gene Name

anti-GGPS1 antibody

Product Synonym Names

GGPPS; GGPPS1

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Purity/Purification

Affinity Purification

Concentration

1mg/ml (lot specific)

Preparation and Storage

Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

300

OMIM

606982

3D Structure

ModBase 3D Structure for O95749

Species

Human

Immunogen

Recombinant protein of human GGPS1

Calculated Molecular Weight

35kDa

Product Categories/Family for anti-GGPS1 antibody

Polyclonal

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-GGPS1 antibody

Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-GGPS1 antibody

WB: 1:500-1:2000
IHC: 1:50-1:200

Other Notes

Small volumes of anti-GGPS1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GGPS1 purchase

MBS129240 is an antibody targeting GGPS1. Also known as GGPS1 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GGPS1. It may not necessarily be applicable to this product.

NCBI GI #

6831549

NCBI GeneID

9453

NCBI Accession #

O95749.1

UniProt Primary Accession #

O95749

UniProt Secondary Accession #

Q5T2C8; Q6NW19; A8MVQ8

UniProt Related Accession #

O95749

NCBI Official Full Name

Geranylgeranyl pyrophosphate synthase

NCBI Official Synonym Full Names

geranylgeranyl diphosphate synthase 1

NCBI Official Symbol

GGPS1

NCBI Official Synonym Symbols

GGPPS; GGPPS1

UniProt Protein Name

Geranylgeranyl pyrophosphate synthase

UniProt Synonym Protein Names

(2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase (EC:2.5.1.1); Farnesyl diphosphate synthase; Farnesyltranstransferase (EC:2.5.1.29); Geranylgeranyl diphosphate synthase; Geranyltranstransferase (EC:2.5.1.10)

Protein Family

Heterodimeric geranylgeranyl pyrophosphate synthase

UniProt Gene Name

GGPS1

UniProt Synonym Gene Names

GGPP synthase; GGPPSase

UniProt Entry Name

GGPPS_HUMAN

NCBI Protein Information

geranylgeranyl pyrophosphate synthase; GGPPSase; GGPP synthase; geranyltranstransferase; farnesyltranstransferase; dimethylallyltranstransferase; farnesyl diphosphate synthase; (2E,6E)-farnesyl diphosphate synthase

UniProt Comments for GGPS1

GGPS1: Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins. Belongs to the FPP/GGPP synthase family.

Protein type: Transferase; Secondary Metabolites Metabolism - terpenoid backbone biosynthesis; EC 2.5.1.10; EC 2.5.1.29; Motility/polarity/chemotaxis; EC 2.5.1.1

Chromosomal Location of Human Ortholog: 1q43

Cellular Component: cytosol

Molecular Function: geranyltranstransferase activity; dimethylallyltranstransferase activity; farnesyltranstransferase activity; metal ion binding

Biological Process: isoprenoid metabolic process; geranylgeranyl diphosphate biosynthetic process; geranyl diphosphate biosynthetic process; farnesyl diphosphate biosynthetic process; cholesterol biosynthetic process

Research Articles on GGPS1

1. Egr-1 most likely does not induce the constitutive activation of Erk1/2 through its target gene GGPS1.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GGPS1 antibody

Reference Product	PubMed Publications
FDPS antibody	>1 publications with GGPS1 and FDPS

Pathways associated with anti-GGPS1 antibody

Products by Pathway	Pathway Diagram
Activation Of Gene Expression By SREBF (SREBP) Pathway antibodies	Activation Of Gene Expression By SREBF (SREBP) Pathway Diagram
Cholesterol Biosynthesis Pathway antibodies	Cholesterol Biosynthesis Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Lipids And Lipoproteins Pathway antibodies	Metabolism Of Lipids And Lipoproteins Pathway Diagram
Regulation Of Cholesterol Biosynthesis By SREBP (SREBF) Pathway antibodies	Regulation Of Cholesterol Biosynthesis By SREBP (SREBF) Pathway Diagram
Terpenoid Backbone Biosynthesis Pathway antibodies	Terpenoid Backbone Biosynthesis Pathway Diagram
Terpenoid Backbone Biosynthesis Pathway antibodies	Terpenoid Backbone Biosynthesis Pathway Diagram
Geranylgeranyl Diphosphate Biosynthesis Pathway antibodies	Geranylgeranyl Diphosphate Biosynthesis Pathway Diagram
Geranylgeranyldiphosphate Biosynthesis Pathway antibodies	Geranylgeranyldiphosphate Biosynthesis Pathway Diagram

Diseases associated with anti-GGPS1 antibody

Disease Name	Pubmed Publications
Insulin Resistance Antibodies	>2 publications with GGPS1 and Insulin Resistance
Skin Diseases Antibodies	>1 publications with GGPS1 and Skin Diseases

Organs/Tissues associated with anti-GGPS1 antibody

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>1 publications with GGPS1 and Bone