Rabbit Anti-PTPRR Polyclonal Antibody – Cat# MBS129338

Western blot analysis of extracts of various cell lines, using PTPRR antibody.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.

PTPRR Antibody – Rabbit Polyclonal

Name: PTPRR Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS129338
Price: 360 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS129338

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

PTPRR, Polyclonal Antibody

Full Product Name

PTPRR Polyclonal Antibody

Product Gene Name

anti-PTPRR antibody

Product Synonym Names

PTPRQ; EC-PTP; PCPTP1; PTP-SL; PTPBR7

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Purity/Purification

Affinity Purification

Concentration

1mg/ml (lot specific)

Preparation and Storage

Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

657

OMIM

602853

3D Structure

ModBase 3D Structure for Q15256

Species

Human

Immunogen

Recombinant protein of human PTPRR

Calculated Molecular Weight

47kDa

Product Categories/Family for anti-PTPRR antibody

Polyclonal

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-PTPRR antibody

Western Blot (WB)

Application Notes for anti-PTPRR antibody

WB: 1:500 - 1:2000

Other Notes

Small volumes of anti-PTPRR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PTPRR purchase

MBS129338 is an antibody targeting PTPRR. Also known as PTPRR Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PTPRR. It may not necessarily be applicable to this product.

NCBI GI #

134039192

NCBI GeneID

5801

NCBI Accession #

Q15256.2

UniProt Primary Accession #

Q15256

UniProt Secondary Accession #

O00342; Q92682; Q9UE65; B2R5Z7; B7Z3J1; F5GXR7

UniProt Related Accession #

Q15256

NCBI Official Full Name

Receptor-type tyrosine-protein phosphatase R

NCBI Official Synonym Full Names

protein tyrosine phosphatase, receptor type, R

NCBI Official Symbol

PTPRR

NCBI Official Synonym Symbols

PTPRQ; EC-PTP; PCPTP1; PTP-SL; PTPBR7

UniProt Protein Name

Receptor-type tyrosine-protein phosphatase R

UniProt Synonym Protein Names

Ch-1PTPase; NC-PTPCOM1; Protein-tyrosine phosphatase PCPTP1

Protein Family

Receptor-type tyrosine-protein phosphatase

UniProt Gene Name

PTPRR

UniProt Synonym Gene Names

ECPTP; PTPRQ; R-PTP-R

UniProt Entry Name

PTPRR_HUMAN

NCBI Protein Information

receptor-type tyrosine-protein phosphatase R; R-PTP-R; NC-PTPCOM1; ch-1PTPase; Ch-1 PTPase; protein-tyrosine phosphatase PCPTP1; protein tyrosine phosphatase Cr1PTPase; protein-tyrosine phosphatase NC-PTPCOM1

UniProt Comments for PTPRR

PTP-SL: Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus. Belongs to the protein-tyrosine phosphatase family. Receptor class 7 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; EC 3.1.3.48; Membrane protein, integral; Receptor protein phosphatase, tyrosine

Chromosomal Location of Human Ortholog: 12q15

Cellular Component: extracellular space; perinuclear region of cytoplasm; integral to membrane; plasma membrane

Molecular Function: protein binding; transmembrane receptor protein tyrosine phosphatase activity; protein tyrosine phosphatase activity; protein kinase binding

Biological Process: in utero embryonic development; protein amino acid dephosphorylation

Research Articles on PTPRR

1. The methylation index of PTPRR recovered from scrapings of uterine cervix adenocarcinomas is significantly higher than in normal controls.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-PTPRR antibody

Products by Pathway	Pathway Diagram
EGFR1 Signaling Pathway antibodies	EGFR1 Signaling Pathway Diagram
MAPK Signaling Pathway antibodies	MAPK Signaling Pathway Diagram
MAPK Signaling Pathway antibodies	MAPK Signaling Pathway Diagram
MAPK Signaling Pathway antibodies	MAPK Signaling Pathway Diagram

Diseases associated with anti-PTPRR antibody

Disease Name	Pubmed Publications
Intestinal Neoplasms Antibodies	>3 publications with PTPRR and Intestinal Neoplasms
Nervous System Diseases Antibodies	>3 publications with PTPRR and Nervous System Diseases
Liver Neoplasms Antibodies	>2 publications with PTPRR and Liver Neoplasms
Uterine Cervical Neoplasms Antibodies	>2 publications with PTPRR and Uterine Cervical Neoplasms
Adenocarcinoma Antibodies	>2 publications with PTPRR and Adenocarcinoma
Liver Diseases Antibodies	>1 publications with PTPRR and Liver Diseases
Neoplasms, Experimental Antibodies	>1 publications with PTPRR and Neoplasms, Experimental
Memory Disorders Antibodies	>1 publications with PTPRR and Memory Disorders
Learning Disorders Antibodies	>1 publications with PTPRR and Learning Disorders

Organs/Tissues associated with anti-PTPRR antibody

Organ/Tissue Name	Pubmed Publications
Nerve Antibodies	>18 publications with PTPRR and Nerve
Brain Antibodies	>17 publications with PTPRR and Brain
Embryonic Tissue Antibodies	>2 publications with PTPRR and Embryonic Tissue
Bone Antibodies	>2 publications with PTPRR and Bone
Uterus Antibodies	>2 publications with PTPRR and Uterus
Cervix Antibodies	>2 publications with PTPRR and Cervix
Intestine Antibodies	>1 publications with PTPRR and Intestine
Placenta Antibodies	>1 publications with PTPRR and Placenta
Kidney Antibodies	>1 publications with PTPRR and Kidney
Uncharacterized Tissue Antibodies	>1 publications with PTPRR and Uncharacterized Tissue