Rabbit Anti-PPFIA1 Polyclonal Antibody – Cat# MBS129349

Western blot analysis of extracts of MDA-MB231 cells, using PPFIA1 antibody.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.

PPFIA1 Antibody – Rabbit Polyclonal

Name: PPFIA1 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS129349
Price: 360 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS129349

The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

PPFIA1, Polyclonal Antibody

Full Product Name

PPFIA1 Polyclonal Antibody

Product Gene Name

anti-PPFIA1 antibody

Product Synonym Names

LIP1; LIP.1; LIPRIN

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Purity/Purification

Affinity Purification

Concentration

1mg/ml (lot specific)

Preparation and Storage

Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

1202

OMIM

611054

3D Structure

ModBase 3D Structure for Q13136

Species

Human

Immunogen

Recombinant protein of human PPFIA1

Calculated Molecular Weight

136kDa

Product Categories/Family for anti-PPFIA1 antibody

Polyclonal

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-PPFIA1 antibody

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Application Notes for anti-PPFIA1 antibody

WB: 1:200-1:2000
IHC: 1:50-1:200
IF: 1:50-1:200

Other Notes

Small volumes of anti-PPFIA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PPFIA1 purchase

MBS129349 is an antibody targeting PPFIA1. Also known as PPFIA1 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PPFIA1. It may not necessarily be applicable to this product.

NCBI GI #

42558969

NCBI GeneID

8500

NCBI Accession #

Q13136.1

UniProt Primary Accession #

Q13136

UniProt Secondary Accession #

Q13135; Q14567; Q8N4I2; A6NLE3

UniProt Related Accession #

Q13136

NCBI Official Full Name

Liprin-alpha-1

NCBI Official Synonym Full Names

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1

NCBI Official Symbol

PPFIA1

NCBI Official Synonym Symbols

LIP1; LIP.1; LIPRIN

UniProt Protein Name

Liprin-alpha-1

UniProt Synonym Protein Names

LAR-interacting protein 1; LIP-1; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1; PTPRF-interacting protein alpha-1

Protein Family

Liprin

UniProt Gene Name

PPFIA1

UniProt Synonym Gene Names

LIP1; LIP-1; PTPRF-interacting protein alpha-1

UniProt Entry Name

LIPA1_HUMAN

NCBI Protein Information

liprin-alpha-1; LIP-1; Liprin-alpha1; LAR-interacting protein 1; PTPRF-interacting protein alpha-1; protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1

UniProt Comments for PPFIA1

liprin alpha 1: a ubiqutous member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Two alternatively spliced isoforms have been described.

Protein type: Motility/polarity/chemotaxis; Cell adhesion

Chromosomal Location of Human Ortholog: 11q13.3

Cellular Component: focal adhesion; cytoplasm; presynaptic active zone; cytosol

Molecular Function: signal transducer activity; protein binding

Biological Process: synaptic transmission; negative regulation of stress fiber formation; glutamate secretion; cell-matrix adhesion; neurotransmitter secretion; signal transduction

Research Articles on PPFIA1

1. PPFIA1 was frequently co-amplified with the Cyclin D1 gene in oral carcinomas and could present a biomarker as well as a novel target for specific gene therapy.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PPFIA1 antibody

Reference Product	PubMed Publications
PTPRF antibody	>8 publications with PPFIA1 and PTPRF
PTPRD antibody	>7 publications with PPFIA1 and PTPRD
ING4 antibody	>2 publications with PPFIA1 and ING4
PPP2CB antibody	>1 publications with PPFIA1 and PPP2CB
PTPRS antibody	>1 publications with PPFIA1 and PTPRS
PPP2CA antibody	>1 publications with PPFIA1 and PPP2CA

Pathways associated with anti-PPFIA1 antibody

Products by Pathway	Pathway Diagram
Acetylcholine Neurotransmitter Release Cycle Pathway antibodies	Acetylcholine Neurotransmitter Release Cycle Pathway Diagram
Dopamine Neurotransmitter Release Cycle Pathway antibodies	Dopamine Neurotransmitter Release Cycle Pathway Diagram
Glutamate Neurotransmitter Release Cycle Pathway antibodies	Glutamate Neurotransmitter Release Cycle Pathway Diagram
Neuronal System Pathway antibodies	Neuronal System Pathway Diagram
Neurotransmitter Release Cycle Pathway antibodies	Neurotransmitter Release Cycle Pathway Diagram
Norepinephrine Neurotransmitter Release Cycle Pathway antibodies	Norepinephrine Neurotransmitter Release Cycle Pathway Diagram
Serotonin Neurotransmitter Release Cycle Pathway antibodies	Serotonin Neurotransmitter Release Cycle Pathway Diagram
Transmission Across Chemical Synapses Pathway antibodies	Transmission Across Chemical Synapses Pathway Diagram

Diseases associated with anti-PPFIA1 antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>3 publications with PPFIA1 and Nervous System Diseases
Mental Disorders Antibodies	>2 publications with PPFIA1 and Mental Disorders
Embryo Loss Antibodies	>1 publications with PPFIA1 and Embryo Loss
Fibrosis Antibodies	>1 publications with PPFIA1 and Fibrosis
Seizures Antibodies	>1 publications with PPFIA1 and Seizures
Inflammation Antibodies	>1 publications with PPFIA1 and Inflammation

Organs/Tissues associated with anti-PPFIA1 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>12 publications with PPFIA1 and Brain
Nerve Antibodies	>7 publications with PPFIA1 and Nerve
Mouth Antibodies	>3 publications with PPFIA1 and Mouth
Embryonic Tissue Antibodies	>3 publications with PPFIA1 and Embryonic Tissue
Bladder Antibodies	>3 publications with PPFIA1 and Bladder
Eye Antibodies	>2 publications with PPFIA1 and Eye
Mammary Gland Antibodies	>2 publications with PPFIA1 and Mammary Gland
Liver Antibodies	>2 publications with PPFIA1 and Liver
Muscle Antibodies	>2 publications with PPFIA1 and Muscle
Skin Antibodies	>2 publications with PPFIA1 and Skin