Rabbit Anti-EFNB1 Polyclonal Antibody – Cat# MBS129468

Western blot analysis of extracts of various cell lines, using EFNB1 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 5s.

EFNB1 Antibody – Rabbit Polyclonal

Name: EFNB1 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS129468
Price: 225 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS129468

The protein encoded by this gene is a type I membrane protein and a ligand of Eph-related receptor tyrosine kinases. It may play a role in cell adhesion and function in the development or maintenance of the nervous system. More details

$225 / 0.02 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

EFNB1, Polyclonal Antibody

Full Product Name

EFNB1 Polyclonal Antibody

Product Gene Name

anti-EFNB1 antibody

Product Synonym Names

CFND; CFNS; EFL3; EPLG2; Elk-L; LERK2

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Purity/Purification

Affinity Purification

Concentration

1mg/ml (lot specific)

Preparation and Storage

Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

346

OMIM

gene 304110

3D Structure

ModBase 3D Structure for P98172

Species

Human

Immunogen

A synthetic peptide of human EFNB1

Calculated Molecular Weight

38kDa

Product Categories/Family for anti-EFNB1 antibody

Polyclonal

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-EFNB1 antibody

Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-EFNB1 antibody

WB: 1:500 - 1:2000
IHC: 1:50 - 1:200

Other Notes

Small volumes of anti-EFNB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EFNB1 purchase

MBS129468 is an antibody targeting EFNB1. Also known as EFNB1 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for EFNB1. It may not necessarily be applicable to this product.

NCBI GI #

1706668

NCBI GeneID

1947

NCBI Accession #

P98172.1

UniProt Primary Accession #

P98172

UniProt Secondary Accession #

D3DVU0

UniProt Related Accession #

P98172

NCBI Official Full Name

Ephrin-B1

NCBI Official Synonym Full Names

ephrin-B1

NCBI Official Symbol

EFNB1

NCBI Official Synonym Symbols

CFND; CFNS; EFB1; EFL3; EPLG2; Elk-L; LERK2

UniProt Protein Name

Ephrin-B1

UniProt Synonym Protein Names

EFL-3; ELK ligand; ELK-L; EPH-related receptor tyrosine kinase ligand 2; LERK-2

Protein Family

Ephrin

UniProt Gene Name

EFNB1

UniProt Synonym Gene Names

EFL3; EPLG2; LERK2; ELK-L; LERK-2

UniProt Entry Name

EFNB1_HUMAN

NCBI Protein Information

ephrin-B1; EFL-3; LERK-2; ELK ligand; ligand of eph-related kinase 2; eph-related receptor tyrosine kinase ligand 2

UniProt Comments for EFNB1

EFNB1: a type I membrane protein of the ephrin family. A ligand of Eph-related receptor tyrosine kinases EphB1 and EphA1. Ephrins and ephrin receptors mediate numerous developmental processes, particularly in the nervous system. Ephrin-B1 may play a role in cell adhesion and functions in the development or maintenance of the nervous system. Binding to its receptor induces the collapse of commissural axons/growth cones in vitro. Induced by TNF-alpha. Expressed in brain, heart, placenta, lung, liver, skeletal muscle, kidney, and pancreas.

Protein type: Membrane protein, integral; Ligand, receptor tyrosine kinase

Chromosomal Location of Human Ortholog: Xq12

Cellular Component: integral to plasma membrane; cytoplasm; plasma membrane; synapse; nucleus; lipid raft

Molecular Function: protein binding; ephrin receptor binding

Biological Process: axon guidance; cell-cell signaling; ephrin receptor signaling pathway; positive regulation of T cell proliferation; cell adhesion; embryonic pattern specification; neural crest cell migration

Disease: Craniofrontonasal Syndrome

Research Articles on EFNB1

1. CNK1 mediates ephrinB1 signaling that promotes cell migration through RhoA and JNK activity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-EFNB1 antibody

Reference Product	PubMed Publications
EPHB2 antibody	>13 publications with EFNB1 and EPHB2
EPHB1 antibody	>10 publications with EFNB1 and EPHB1
EPHB3 antibody	>3 publications with EFNB1 and EPHB3
EPHB6 antibody	>3 publications with EFNB1 and EPHB6
SRC antibody	>3 publications with EFNB1 and SRC
PTPN13 antibody	>2 publications with EFNB1 and PTPN13
RGS3 antibody	>1 publications with EFNB1 and RGS3

Pathways associated with anti-EFNB1 antibody

Products by Pathway	Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
EPH-Ephrin Signaling Pathway antibodies	EPH-Ephrin Signaling Pathway Diagram
EPH-ephrin Mediated Repulsion Of Cells Pathway antibodies	EPH-ephrin Mediated Repulsion Of Cells Pathway Diagram
EPHB Forward Signaling Pathway antibodies	EPHB Forward Signaling Pathway Diagram
EPHB-mediated Forward Signaling Pathway antibodies	EPHB-mediated Forward Signaling Pathway Diagram
Ephrin B Reverse Signaling Pathway antibodies	Ephrin B Reverse Signaling Pathway Diagram
Ephrin Signaling Pathway antibodies	Ephrin Signaling Pathway Diagram

Diseases associated with anti-EFNB1 antibody

Disease Name	Pubmed Publications
Craniosynostoses Antibodies	>16 publications with EFNB1 and Craniosynostoses
Hypertelorism Antibodies	>13 publications with EFNB1 and Hypertelorism
Frontonasal dysplasia Antibodies	>8 publications with EFNB1 and Frontonasal dysplasia
Craniofrontonasal dysplasia Antibodies	>7 publications with EFNB1 and Craniofrontonasal dysplasia
Nervous System Diseases Antibodies	>7 publications with EFNB1 and Nervous System Diseases
Abnormalities, Multiple Antibodies	>5 publications with EFNB1 and Abnormalities, Multiple
Inflammation Antibodies	>4 publications with EFNB1 and Inflammation
Necrosis Antibodies	>3 publications with EFNB1 and Necrosis
Brain Diseases Antibodies	>3 publications with EFNB1 and Brain Diseases
Neurobehavioral Manifestations Antibodies	>2 publications with EFNB1 and Neurobehavioral Manifestations

Organs/Tissues associated with anti-EFNB1 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>20 publications with EFNB1 and Brain
Bone Antibodies	>18 publications with EFNB1 and Bone
Embryonic Tissue Antibodies	>8 publications with EFNB1 and Embryonic Tissue
Vascular Antibodies	>7 publications with EFNB1 and Vascular
Connective Tissue Antibodies	>4 publications with EFNB1 and Connective Tissue
Muscle Antibodies	>4 publications with EFNB1 and Muscle
Spleen Antibodies	>3 publications with EFNB1 and Spleen
Eye Antibodies	>3 publications with EFNB1 and Eye
Ovary Antibodies	>2 publications with EFNB1 and Ovary
Kidney Antibodies	>2 publications with EFNB1 and Kidney