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ABCG1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS129616
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The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1,… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ABCG1, Polyclonal Antibody
Full Product Name
ABCG1 Polyclonal Antibody
Product Gene Name
anti-ABCG1 antibody
Product Synonym Names
ABC8; WHITE1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
678
OMIM
603076
3D Structure
ModBase 3D Structure for P45844
Species
Human
Immunogen
Recombinant protein of human ABCG1
Calculated Molecular Weight
76kDa

Product Categories/Family for anti-ABCG1 antibody

Polyclonal
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-ABCG1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ABCG1 antibody
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200

Western Blot (WB) of anti-ABCG1 antibody

Western blot analysis of extracts of various cell lines, using ABCG1 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.
Rabbit Anti-ABCG1 Polyclonal Antibody – Cat# MBS129616

Other Notes

Small volumes of anti-ABCG1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ABCG1 purchase

MBS129616 is an antibody targeting ABCG1. Also known as ABCG1 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ABCG1. It may not necessarily be applicable to this product.

NCBI GI #
17433715
NCBI GeneID
9619
NCBI Accession #
P45844.3
UniProt Primary Accession #
P45844
UniProt Secondary Accession #
Q86SU8; Q96L76; Q9BXK6; Q9BXK7; Q9BXK8; Q9BXK9; Q9BXL0; Q9BXL1; Q9BXL2; Q9BXL3; Q9BXL4
UniProt Related Accession #
P45844
NCBI Official Full Name
ATP-binding cassette sub-family G member 1
NCBI Official Synonym Full Names
ATP-binding cassette, sub-family G (WHITE), member 1
NCBI Official Symbol
ABCG1
NCBI Official Synonym Symbols
ABC8; WHITE1
UniProt Protein Name
ATP-binding cassette sub-family G member 1
UniProt Synonym Protein Names
ATP-binding cassette transporter 8; White protein homolog
Protein Family
ABC transporter G family
UniProt Gene Name
ABCG1
UniProt Synonym Gene Names
ABC8; WHT1
UniProt Entry Name
ABCG1_HUMAN
NCBI Protein Information
ATP-binding cassette sub-family G member 1; ABC transporter 8; homolog of Drosophila white; ATP-binding cassette transporter 8; ATP-binding cassette transporter member 1 of subfamily G; white protein homolog (ATP-binding cassette transporter 8)

UniProt Comments for ABCG1

ABCG1: Transporter involved in macrophage lipid homeostasis. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages. Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. 8 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter; Transporter, ABC family; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: nucleoplasm; Golgi membrane; Golgi apparatus; endoplasmic reticulum membrane; recycling endosome; intracellular membrane-bound organelle; mitochondrion; integral to plasma membrane; plasma membrane; endosome; external side of plasma membrane

Molecular Function: protein dimerization activity; protein binding; protein homodimerization activity; phospholipid transporter activity; protein heterodimerization activity; cholesterol transporter activity; cholesterol binding; toxin transporter activity; phospholipid binding; sterol-transporting ATPase activity; ADP binding; ATP binding

Biological Process: cholesterol metabolic process; detection of hormone stimulus; response to high density lipoprotein stimulus; positive regulation of cholesterol biosynthetic process; cholesterol efflux; lipoprotein metabolic process; intracellular cholesterol transport; response to lipid; response to organic substance; cholesterol homeostasis; amyloid precursor protein catabolic process; reverse cholesterol transport; phospholipid efflux; regulation of transcription, DNA-dependent; transmembrane transport; phospholipid homeostasis
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Research Articles on ABCG1

1. I human macrophages, polyunsaturated fatty acids such as EPA have an effect on the cholesterol homeostasis in macrophages, and they can change the expression of ABCG1 gene.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ABCG1 antibody

 Products by Pathway  Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC-family Proteins Mediated Transport Pathway antibodies  ABC-family Proteins Mediated Transport Pathway Diagram
 ABCA Transporters In Lipid Homeostasis Pathway antibodies  ABCA Transporters In Lipid Homeostasis Pathway Diagram
 HDL-mediated Lipid Transport Pathway antibodies  HDL-mediated Lipid Transport Pathway Diagram
 Lipid Digestion, Mobilization, And Transport Pathway antibodies  Lipid Digestion, Mobilization, And Transport Pathway Diagram
 Lipoprotein Metabolism Pathway antibodies  Lipoprotein Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Nuclear Receptors In Lipid Metabolism And Toxicity Pathway antibodies  Nuclear Receptors In Lipid Metabolism And Toxicity Pathway Diagram

Diseases associated with anti-ABCG1 antibody

 Disease Name  Pubmed Publications
 Atherosclerosis Antibodies  >296 publications with ABCG1 and Atherosclerosis
 Cardiovascular Diseases Antibodies  >202 publications with ABCG1 and Cardiovascular Diseases
 Inflammation Antibodies  >101 publications with ABCG1 and Inflammation
 Dyslipidemias Antibodies  >55 publications with ABCG1 and Dyslipidemias
 Liver Diseases Antibodies  >52 publications with ABCG1 and Liver Diseases
 Fatty Liver Antibodies  >47 publications with ABCG1 and Fatty Liver
 Hyperlipidemias Antibodies  >36 publications with ABCG1 and Hyperlipidemias
 Hypercholesterolemia Antibodies  >33 publications with ABCG1 and Hypercholesterolemia
 Necrosis Antibodies  >31 publications with ABCG1 and Necrosis
 Nervous System Diseases Antibodies  >30 publications with ABCG1 and Nervous System Diseases

Organs/Tissues associated with anti-ABCG1 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >319 publications with ABCG1 and Liver
 Blood Antibodies  >210 publications with ABCG1 and Blood
 Brain Antibodies  >54 publications with ABCG1 and Brain
 Lung Antibodies  >37 publications with ABCG1 and Lung
 Muscle Antibodies  >36 publications with ABCG1 and Muscle
 Intestine Antibodies  >22 publications with ABCG1 and Intestine
 Kidney Antibodies  >22 publications with ABCG1 and Kidney
 Pancreas Antibodies  >12 publications with ABCG1 and Pancreas
 Connective Tissue Antibodies  >12 publications with ABCG1 and Connective Tissue
 Spleen Antibodies  >12 publications with ABCG1 and Spleen
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