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F-Box Only Protein 31 (FBXO31) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1296361

MBS1296361 is a recombinant protein targeting FBXO31. Also known as Recombinant Human F-box only protein 31 (FBXO31). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1345 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
F-box only protein 31 (FBXO31), Recombinant Protein
Full Product Name
Recombinant Human F-box only protein 31 (FBXO31)
Product Gene Name
FBXO31 recombinant protein
Product Synonym Gene Name
FBXO31
Sequence
MAVCARLCGV GPSRGCRRRQ QRRGPAETAA ADSEPDTDPE EERIEASAGV GGGLCAGPSP PPPRCSLLEL PPELLVEIFA SLPGTDLPSL AQVCTKFRRI LHTDTIWRRR CREEYGVCEN LRKLEITGVS CRDVYAKLLH RYRHILGLWQ PDIGPYGGLL NVVVDGLFII GWMYLPPHDP HVDDPMRFKP LFRIHLMERK AATVECMYGH KGPHHGHIQI VKKDEFSTKC NQTDHHRMSG GRQEEFRTWL REEWGRTLED IFHEHMQELI LMKFIYTSQY DNCLTYRRIY LPPSRPDDLI KPGLFKGTYG SHGLEIVMLS FHGRRARGTK ITGDPNIPAG QQTVEIDLRH RIQLPDLENQ RNFNELSRIV LEVRERVRQE QQEGGHEAGE GRGRQGPRES QPSPAQPRAE APSKGPDGTP GEDGGEPGDA VAAAEQPAQC GQGQPFVLPV GVSSRNEDYP RTCRMCFYGT GLIAGHGFTS PERTPGVFIL FDEDRFGFVW LELKSFSLYS RVQATFRNAD APSPQAFDEM LKNIQSLTS
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
49,039 Da
Sequence Positions
1-539, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
609102
3D Structure
ModBase 3D Structure for Q5XUX0
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of FBXO31 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FBXO31. It may not necessarily be applicable to this product.

NCBI GI #
544186107
NCBI GeneID
79791
NCBI Accession #
NP_001269612.1
UniProt Primary Accession #
Q5XUX0
UniProt Secondary Accession #
Q5K680; Q8WYV1; Q96D73; Q9UFV4
UniProt Related Accession #
Q5XUX0
GenBank Nucleotide #
NM_001282683.1
NCBI Official Full Name
F-box only protein 31 isoform 2
NCBI Official Synonym Full Names
F-box protein 31
NCBI Official Symbol
FBXO31
NCBI Official Synonym Symbols
FBX14; Fbx31; MRT45; FBXO14; pp2386
UniProt Protein Name
F-box only protein 31
Protein Family
F-box only protein
UniProt Gene Name
FBXO31
UniProt Synonym Gene Names
FBX14; FBX31
NCBI Protein Information
F-box only protein 31

NCBI Summary for FBXO31

This gene is a member of the F-box family. Members are classified into three classes according to the substrate interaction domain, FBW for WD40 repeats, FBL for leucing-rich repeats, and FBXO for other domains. This protein, classified into the last category because of the lack of a recognizable substrate binding domain, has been proposed to be a component of the SCF ubiquitination complex. It is thought to bind and recruit substrate for ubiquitination and degradation. This protein may have a role in regulating the cell cycle as well as dendrite growth and neuronal migration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
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UniProt Comments for FBXO31

Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. Specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. May act as a tumor suppressor.
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Research Articles on FBXO31

1. in addition to revealing that FBXO31 is an independent prognostic marker for esophageal squamous cell carcinoma , our findings substantiate a novel regulatory role of FBXO31 in tumorigenesis and drug resistance of esophageal squamous cell carcinoma

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with FBXO31 recombinant protein

 Reference Product  PubMed Publications
 SKP1 recombinant protein  >3 publications with FBXO31 and SKP1
 RBX1 recombinant protein  >1 publications with FBXO31 and RBX1
 CUL1 recombinant protein  >1 publications with FBXO31 and CUL1

Diseases associated with FBXO31 recombinant protein

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >8 publications with FBXO31 and Neoplasms
 Breast Neoplasms Antibodies  >3 publications with FBXO31 and Breast Neoplasms
 Nervous System Diseases Antibodies  >1 publications with FBXO31 and Nervous System Diseases
 Microcephaly Antibodies  >1 publications with FBXO31 and Microcephaly
 Nervous System Malformations Antibodies  >1 publications with FBXO31 and Nervous System Malformations
 Carcinoma, Hepatocellular Antibodies  >1 publications with FBXO31 and Carcinoma, Hepatocellular
 Disease Models, Animal Antibodies  >1 publications with FBXO31 and Disease Models, Animal
 Liver Neoplasms Antibodies  >1 publications with FBXO31 and Liver Neoplasms
 Adenocarcinoma Antibodies  >1 publications with FBXO31 and Adenocarcinoma
 Liver Diseases Antibodies  >1 publications with FBXO31 and Liver Diseases

Organs/Tissues associated with FBXO31 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Adrenal Gland Antibodies  >1 publications with FBXO31 and Adrenal Gland
 Kidney Antibodies  >1 publications with FBXO31 and Kidney
 Liver Antibodies  >1 publications with FBXO31 and Liver
 Embryonic Tissue Antibodies  >1 publications with FBXO31 and Embryonic Tissue
 Eye Antibodies  >1 publications with FBXO31 and Eye
 Prostate Antibodies  >1 publications with FBXO31 and Prostate
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