Rabbit Anti-KIFAP3 Polyclonal Antibody – Cat# MBS129663

Western blot analysis of extracts of various cell lines, using KIFAP3 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 5s.

KIFAP3 Antibody – Rabbit Polyclonal

Name: KIFAP3 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS129663
Price: 225 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS129663

The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is… More details

$225 / 0.02 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

KIFAP3, Polyclonal Antibody

Full Product Name

KIFAP3 Polyclonal Antibody

Product Gene Name

anti-KIFAP3 antibody

Product Synonym Names

FLA3; KAP3; SMAP; KAP-1; KAP-3; Smg-GDS; dJ190I16.1

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Purity/Purification

Affinity Purification

Concentration

1mg/ml (lot specific)

Preparation and Storage

Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

792

OMIM

601836

3D Structure

ModBase 3D Structure for Q92845

Species

Human

Immunogen

Recombinant protein of human KIFAP3

Calculated Molecular Weight

91kDa

Product Categories/Family for anti-KIFAP3 antibody

Polyclonal

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-KIFAP3 antibody

Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-KIFAP3 antibody

WB: 1:500-1:2000
IHC: 1:50-1:200

Other Notes

Small volumes of anti-KIFAP3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KIFAP3 purchase

MBS129663 is an antibody targeting KIFAP3. Also known as KIFAP3 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KIFAP3. It may not necessarily be applicable to this product.

NCBI GI #

73920216

NCBI GeneID

22920

NCBI Accession #

Q92845.2

UniProt Primary Accession #

Q92845

UniProt Secondary Accession #

Q8NHU7; Q9H416; B1AKU4; B1AKU5; B2RDL1; B7Z8A3; F5H591

UniProt Related Accession #

Q92845

NCBI Official Full Name

Kinesin-associated protein 3

NCBI Official Synonym Full Names

kinesin-associated protein 3

NCBI Official Symbol

KIFAP3

NCBI Official Synonym Symbols

FLA3; KAP3; SMAP; KAP-1; KAP-3; Smg-GDS; dJ190I16.1

UniProt Protein Name

Kinesin-associated protein 3

UniProt Synonym Protein Names

Smg GDS-associated protein

Protein Family

Kinesin-associated protein

UniProt Gene Name

KIFAP3

UniProt Synonym Gene Names

KIF3AP; SMAP; KAP-3; KAP3

UniProt Entry Name

KIFA3_HUMAN

NCBI Protein Information

kinesin-associated protein 3; smg GDS-associated protein; small G protein GDP dissociation stimulator

UniProt Comments for KIFAP3

KIFAP3: Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Binds to the tail domain of the KIF3A/KIF3B heterodimer to form a heterotrimeric KIF3 complex and may regulate the membrane binding of this complex.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 1q24.2

Cellular Component: microtubule cytoskeleton; Golgi apparatus; centrosome; condensed nuclear chromosome; endoplasmic reticulum; spindle microtubule; kinesin II complex; axoneme; cytosol; photoreceptor connecting cilium

Molecular Function: protein binding; kinesin binding

Biological Process: negative regulation of cell proliferation; protein localization; positive regulation of calcium-dependent cell-cell adhesion; organelle organization and biogenesis; antigen processing and presentation of exogenous peptide antigen via MHC class II; protein complex assembly; blood coagulation; signal transduction; microtubule-based movement; microtubule-based process; negative regulation of apoptosis

Research Articles on KIFAP3

1. The incidence of the motor neuron-predominant amyotrophic lateral sclerosis phenotype in the patients of this cohort supports the hypothesis that the SNP within the KIFAP3 gene is a potential modifier of the amyotrophic lateral sclerosis phenotype

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-KIFAP3 antibody

Reference Product	PubMed Publications
KIF3A antibody	>6 publications with KIFAP3 and KIF3A
KIF3B antibody	>3 publications with KIFAP3 and KIF3B
CHAT antibody	>1 publications with KIFAP3 and CHAT

Pathways associated with anti-KIFAP3 antibody

Products by Pathway	Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Assembly Of The Primary Cilium Pathway antibodies	Assembly Of The Primary Cilium Pathway Diagram
Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies	Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Intraflagellar Transport Pathway antibodies	Intraflagellar Transport Pathway Diagram
Kinesins Pathway antibodies	Kinesins Pathway Diagram
MHC Class II Antigen Presentation Pathway antibodies	MHC Class II Antigen Presentation Pathway Diagram
Membrane Trafficking Pathway antibodies	Membrane Trafficking Pathway Diagram
Organelle Biogenesis And Maintenance Pathway antibodies	Organelle Biogenesis And Maintenance Pathway Diagram

Diseases associated with anti-KIFAP3 antibody

Disease Name	Pubmed Publications
Hypertrophy Antibodies	>1 publications with KIFAP3 and Hypertrophy
Fibrosis Antibodies	>1 publications with KIFAP3 and Fibrosis
Necrosis Antibodies	>1 publications with KIFAP3 and Necrosis

Organs/Tissues associated with anti-KIFAP3 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>6 publications with KIFAP3 and Brain
Blood Antibodies	>2 publications with KIFAP3 and Blood
Spinal Cord Antibodies	>1 publications with KIFAP3 and Spinal Cord
Muscle Antibodies	>1 publications with KIFAP3 and Muscle
Vascular Antibodies	>1 publications with KIFAP3 and Vascular
Testis Antibodies	>1 publications with KIFAP3 and Testis