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KIF1B Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS129754
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This gene encodes a motor protein that transports mitochondria and synaptic vesicle precursors. Mutations in this gene cause Charcot-Marie-Tooth disease, type 2A1. More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
KIF1B, Polyclonal Antibody
Full Product Name
KIF1B Polyclonal Antibody
Product Gene Name
anti-KIF1B antibody
Product Synonym Names
KLP; CMT2; CMT2A; CMT2A1; HMSNII; NBLST1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
1816
OMIM
phenotype 605995
3D Structure
ModBase 3D Structure for O60333
Species
Human
Immunogen
Recombinant protein of human KIF1B
Calculated Molecular Weight
204kDa

Product Categories/Family for anti-KIF1B antibody

Polyclonal
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-KIF1B antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-KIF1B antibody
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200

Western Blot (WB) of anti-KIF1B antibody

Western blot analysis of extracts of SKOV3 cells, using KIF1B antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.
Rabbit Anti-KIF1B Polyclonal Antibody – Cat# MBS129754

Immunohistochemistry (IHC) of anti-KIF1B antibody

Immunohistochemistry of paraffin-embedded human liver injury using KIF1B Antibody at dilution of 1:100 (40x lens).
Rabbit Anti-KIF1B Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS129754

Immunohistochemistry (IHC) of anti-KIF1B antibody

Immunohistochemistry of paraffin-embedded rat spinal cord using KIF1B Antibody at dilution of 1:100 (40x lens).
Rabbit Anti-KIF1B Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS129754

Immunohistochemistry (IHC) of anti-KIF1B antibody

Immunohistochemistry of paraffin-embedded rat brain using KIF1B Antibody at dilution of 1:100 (40x lens).
Rabbit Anti-KIF1B Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS129754

Immunohistochemistry (IHC) of anti-KIF1B antibody

Immunohistochemistry of paraffin-embedded human liver cancer using KIF1B Antibody at dilution of 1:100 (40x lens).
Rabbit Anti-KIF1B Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS129754

Immunohistochemistry (IHC) of anti-KIF1B antibody

Immunohistochemistry of paraffin-embedded mouse lung using KIF1B Antibody at dilution of 1:100 (40x lens).
Rabbit Anti-KIF1B Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS129754

Other Notes

Small volumes of anti-KIF1B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KIF1B purchase

MBS129754 is an antibody targeting KIF1B. Also known as KIF1B Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KIF1B. It may not necessarily be applicable to this product.

NCBI GI #
116242605
NCBI GeneID
23095
NCBI Accession #
O60333.5
UniProt Primary Accession #
O60333
UniProt Secondary Accession #
Q4VXC3; Q4VXC4; Q4VXC5; Q4VXC6; Q96Q94; Q9BV80; Q9P280; A6NFS8; A6NKQ4
UniProt Related Accession #
O60333
NCBI Official Full Name
Kinesin-like protein KIF1B
NCBI Official Synonym Full Names
kinesin family member 1B
NCBI Official Symbol
KIF1B
NCBI Official Synonym Symbols
KLP; CMT2; CMT2A; CMT2A1; HMSNII; NBLST1
UniProt Protein Name
Kinesin-like protein KIF1B
Protein Family
Kinesin-like protein
UniProt Gene Name
KIF1B
UniProt Synonym Gene Names
KIAA0591; KIAA1448; Klp
UniProt Entry Name
KIF1B_HUMAN
NCBI Protein Information
kinesin-like protein KIF1B; kinesin superfamily protein KIF1B

UniProt Comments for KIF1B

KIF1B: a member of the kinesin motor protein family. Motor for anterograde transport of mitochondria. May play a role in synaptic vesicle transport. Has a microtubule plus end-directed motility. Aberrant expression seen in neuroblastoma. Mutated in Charcot-Marie-Tooth disease.

Protein type: Microtubule-binding; Motor

Chromosomal Location of Human Ortholog: 1p36.2

Cellular Component: microtubule; kinesin complex; neuron projection; microtubule associated complex; cytoplasmic vesicle membrane; mitochondrion; cytoplasmic vesicle

Molecular Function: protein binding; kinesin binding; plus-end-directed microtubule motor activity; microtubule binding; ATPase activity; microtubule motor activity; ATP binding

Biological Process: vesicle-mediated transport; apoptosis; metabolic process; neuromuscular synaptic transmission; nerve-nerve synaptic transmission; cytoskeleton-dependent intracellular transport; anterograde axon cargo transport; microtubule-based movement; mitochondrion transport along microtubule

Disease: Charcot-marie-tooth Disease, Axonal, Type 2a1; Neuroblastoma, Susceptibility To; Pheochromocytoma
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Research Articles on KIF1B

1. The meta-analysis showed a significant association between kinesin family member 1B (KIF1B) single nucleotide polymorphism (rs17401966) and hepatocellular carcinoma (HCC).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-KIF1B antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >41 publications with KIF1B and Nervous System Diseases
 Multiple Sclerosis Antibodies  >13 publications with KIF1B and Multiple Sclerosis
 Neuroblastoma Antibodies  >13 publications with KIF1B and Neuroblastoma
 Carcinoma, Hepatocellular Antibodies  >12 publications with KIF1B and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >11 publications with KIF1B and Liver Diseases
 Adenocarcinoma Antibodies  >9 publications with KIF1B and Adenocarcinoma
 Liver Neoplasms Antibodies  >8 publications with KIF1B and Liver Neoplasms
 Pheochromocytoma Antibodies  >8 publications with KIF1B and Pheochromocytoma
 Disease Models, Animal Antibodies  >7 publications with KIF1B and Disease Models, Animal
 Nerve Degeneration Antibodies  >3 publications with KIF1B and Nerve Degeneration

Organs/Tissues associated with anti-KIF1B antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >44 publications with KIF1B and Nerve
 Brain Antibodies  >20 publications with KIF1B and Brain
 Muscle Antibodies  >11 publications with KIF1B and Muscle
 Liver Antibodies  >11 publications with KIF1B and Liver
 Eye Antibodies  >5 publications with KIF1B and Eye
 Adrenal Gland Antibodies  >3 publications with KIF1B and Adrenal Gland
 Spinal Cord Antibodies  >3 publications with KIF1B and Spinal Cord
 Pancreas Antibodies  >2 publications with KIF1B and Pancreas
 Blood Antibodies  >2 publications with KIF1B and Blood
 Kidney Antibodies  >2 publications with KIF1B and Kidney
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