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MYOG Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS129878
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Myogenin is a muscle-specific transcription factor that can induce myogenesis in a variety of cell types in tissue culture. It is a member of a large family of proteins related by sequence homology, the helix-loop-helix (HLH) proteins. It is essential for the… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
MYOG, Polyclonal Antibody
Full Product Name
MYOG Polyclonal Antibody
Product Gene Name
anti-MYOG antibody
Product Synonym Names
MYF4; myf-4; bHLHc3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
224
OMIM
159980
3D Structure
ModBase 3D Structure for P15173
Species
Human
Immunogen
Recombinant protein of human MYOG
Calculated Molecular Weight
25kDa

Product Categories/Family for anti-MYOG antibody

Polyclonal
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-MYOG antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-MYOG antibody
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200

Western Blot (WB) of anti-MYOG antibody

Western blot analysis of extracts of various cell lines, using MYOG antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.
Rabbit Anti-MYOG Polyclonal Antibody – Cat# MBS129878

Immunohistochemistry (IHC) of anti-MYOG antibody

Immunohistochemistry of paraffin-embedded rat ovary using MYOG antibody at dilution of 1:100 (20x lens).
Rabbit Anti-MYOG Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS129878

Immunohistochemistry (IHC) of anti-MYOG antibody

Immunohistochemistry of paraffin-embedded human lung cancer using MYOG antibody at dilution of 1:100 (40x lens).
Rabbit Anti-MYOG Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS129878

Other Notes

Small volumes of anti-MYOG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MYOG purchase

MBS129878 is an antibody targeting MYOG. Also known as MYOG Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MYOG. It may not necessarily be applicable to this product.

NCBI GI #
127625
NCBI GeneID
4656
NCBI Accession #
P15173.2
UniProt Primary Accession #
P15173
UniProt Secondary Accession #
Q53XW6
UniProt Related Accession #
P15173
NCBI Official Full Name
Myogenin
NCBI Official Synonym Full Names
myogenin (myogenic factor 4)
NCBI Official Symbol
MYOG
NCBI Official Synonym Symbols
MYF4; myf-4; bHLHc3
UniProt Protein Name
Myogenin
UniProt Synonym Protein Names
Class C basic helix-loop-helix protein 3; bHLHc3; Myogenic factor 4; Myf-4
Protein Family
Myogenin
UniProt Gene Name
MYOG
UniProt Synonym Gene Names
BHLHC3; MYF4; bHLHc3; Myf-4
UniProt Entry Name
MYOG_HUMAN
NCBI Protein Information
myogenin; myogenic factor 4; class C basic helix-loop-helix protein 3

UniProt Comments for MYOG

myogenin: Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 1q31-q41

Cellular Component: nucleoplasm; transcription factor complex; nucleus

Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; protein heterodimerization activity; chromatin DNA binding; sequence-specific DNA binding; transcription factor activity

Biological Process: skeletal muscle development; ossification; muscle cell fate commitment; skeletal muscle fiber development; response to denervation involved in regulation of muscle adaptation; response to electrical stimulus involved in regulation of muscle adaptation; response to muscle activity involved in regulation of muscle adaptation; cell cycle; mRNA transcription from RNA polymerase II promoter; positive regulation of myoblast differentiation; negative regulation of cell proliferation; muscle cell differentiation; positive regulation of muscle atrophy; striated muscle atrophy; positive regulation of skeletal muscle fiber development; positive regulation of muscle cell differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of satellite cell proliferation
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Research Articles on MYOG

1. results indicate that myogenin is a positive regulator in transcriptional regulation of MEGF10 in skeletal muscle

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MYOG antibody

 Reference Product  PubMed Publications
 MYOD1 antibody  >168 publications with MYOG and MYOD1
 MEF2A antibody  >14 publications with MYOG and MEF2A
 MEF2C antibody  >14 publications with MYOG and MEF2C
 SRF antibody  >9 publications with MYOG and SRF
 MAPK14 antibody  >2 publications with MYOG and MAPK14
 TCF3 antibody  >2 publications with MYOG and TCF3
 CSRP3 antibody  >1 publications with MYOG and CSRP3

Pathways associated with anti-MYOG antibody

 Products by Pathway  Pathway Diagram
 CDO In Myogenesis Pathway antibodies  CDO In Myogenesis Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Hypertrophy Model Pathway antibodies  Hypertrophy Model Pathway Diagram
 Id Signaling Pathway antibodies  Id Signaling Pathway Diagram
 Myogenesis Pathway antibodies  Myogenesis Pathway Diagram
 Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway antibodies  Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway Diagram

Diseases associated with anti-MYOG antibody

 Disease Name  Pubmed Publications
 Atrophy Antibodies  >34 publications with MYOG and Atrophy
 Hypertrophy Antibodies  >31 publications with MYOG and Hypertrophy
 Necrosis Antibodies  >21 publications with MYOG and Necrosis
 Fibrosis Antibodies  >16 publications with MYOG and Fibrosis
 Inflammation Antibodies  >13 publications with MYOG and Inflammation
 Insulin Resistance Antibodies  >11 publications with MYOG and Insulin Resistance
 Cell Transformation, Neoplastic Antibodies  >9 publications with MYOG and Cell Transformation, Neoplastic
 Hyperplasia Antibodies  >8 publications with MYOG and Hyperplasia
 Chromosome Aberrations Antibodies  >7 publications with MYOG and Chromosome Aberrations
 Kidney Diseases Antibodies  >7 publications with MYOG and Kidney Diseases

Organs/Tissues associated with anti-MYOG antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >789 publications with MYOG and Muscle
 Nerve Antibodies  >54 publications with MYOG and Nerve
 Eye Antibodies  >9 publications with MYOG and Eye
 Placenta Antibodies  >2 publications with MYOG and Placenta
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