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Cyclin-Dependent Kinase 19 (CDK19) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1301746

This gene encodes a protein that is one of the components of the Mediator coactivator complex. The Mediator complex is a multiprotein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase… More details

$1300 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Cyclin-dependent kinase 19 (CDK19), Recombinant Protein
Full Product Name
Recombinant Human Cyclin-dependent kinase 19 (CDK19)
Product Gene Name
CDK19 recombinant protein
Product Synonym Gene Name
CDK19
Sequence
MDYDFKAKLA AERERVEDLF EYEGCKVGRG TYGHVYKARR KDGKDEKEYA LKQIEGTGIS MSACREIALL RELKHPNVIA LQKVFLSHSD RKVWLLFDYA EHDLWHIIKF HRASKANKKP MQLPRSMVKS LLYQILDGIH YLHANWVLHR DLKPANILVM GEGPERGRVK IADMGFARLF NSPLKPLADL DPVVVTFWYR APELLLGARH YTKAIDIWAI GCIFAELLTS EPIFHCRQED IKTSNPFHHD QLDRIFSVMG FPADKDWEDI RKMPEYPTLQ KDFRRTTYAN SSLIKYMEKH KVKPDSKVFL LLQKLLTMDP TKRITSEQAL QDPYFQEDPL PTLDVFAGCQ IPYPKREFLN EDDPEEKGDK NQQQQQNQHQ QPTAPPQQAA APPQAPPPQQ NSTQTNGTAG GAGAGVGGTG AGLQHSQDSS LNQVPPNKKP RLGPSGANSG GPVMPSDYQH SSSRLNYQSS VQGSSQSQST LGYSSSSQQS SQYHPSHQAH RY
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
49,870 Da
Sequence Positions
1-502, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
614720
3D Structure
ModBase 3D Structure for Q9BWU1
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CDK19 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CDK19 purchase

MBS1301746 is a recombinant protein targeting CDK19. Also known as Recombinant Human Cyclin-dependent kinase 19 (CDK19). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for CDK19. It may not necessarily be applicable to this product.

NCBI GI #
665821250
NCBI GeneID
23097
NCBI Accession #
NP_001287889.1
UniProt Primary Accession #
Q9BWU1
UniProt Secondary Accession #
Q5JQZ7; Q5JR00; Q8TC78; Q9UPX2
UniProt Related Accession #
Q9BWU1
GenBank Nucleotide #
NM_001300960.1
NCBI Official Full Name
cyclin-dependent kinase 19 isoform 2
NCBI Official Synonym Full Names
cyclin dependent kinase 19
NCBI Official Symbol
CDK19
NCBI Official Synonym Symbols
CDK11; CDC2L6; bA346C16.3
UniProt Protein Name
Cyclin-dependent kinase 19
UniProt Synonym Protein Names
CDC2-related protein kinase 6; Cell division cycle 2-like protein kinase 6; Cell division protein kinase 19; Cyclin-dependent kinase 11; Death-preventing kinase
Protein Family
Cyclin-dependent kinase
UniProt Gene Name
CDK19
UniProt Synonym Gene Names
CDC2L6; CDK11; KIAA1028
NCBI Protein Information
cyclin-dependent kinase 19

NCBI Summary for CDK19

This gene encodes a protein that is one of the components of the Mediator co-activator complex. The Mediator complex is a multi-protein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]
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Research Articles on CDK19

1. Moreover, it identified CDK19 and CDK8 to be specifically overexpressed during prostate cancer progression, highlighting their potential as novel therapeutic targets in advanced prostate cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CDK19 recombinant protein

 Reference Product  PubMed Publications
 CCNC recombinant protein  >4 publications with CDK19 and CCNC
 MED12 recombinant protein  >2 publications with CDK19 and MED12
 MED13 recombinant protein  >1 publications with CDK19 and MED13

Pathways associated with CDK19 recombinant protein

 Products by Pathway  Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 PPARA Activates Gene Expression Pathway antibodies  PPARA Activates Gene Expression Pathway Diagram
 Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway antibodies  Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway Diagram
 Transcriptional Regulation Of White Adipocyte Differentiation Pathway antibodies  Transcriptional Regulation Of White Adipocyte Differentiation Pathway Diagram

Diseases associated with CDK19 recombinant protein

 Disease Name  Pubmed Publications
 Neurobehavioral Manifestations Antibodies  >1 publications with CDK19 and Neurobehavioral Manifestations
 Fetal Growth Retardation Antibodies  >1 publications with CDK19 and Fetal Growth Retardation
 Congenital Abnormalities Antibodies  >1 publications with CDK19 and Congenital Abnormalities
 Nervous System Diseases Antibodies  >1 publications with CDK19 and Nervous System Diseases
 Adenocarcinoma Antibodies  >1 publications with CDK19 and Adenocarcinoma

Organs/Tissues associated with CDK19 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Lymph Antibodies  >1 publications with CDK19 and Lymph
 Eye Antibodies  >1 publications with CDK19 and Eye
 Lymph Node Antibodies  >1 publications with CDK19 and Lymph Node
 Bone Antibodies  >1 publications with CDK19 and Bone
 Prostate Antibodies  >1 publications with CDK19 and Prostate
 Brain Antibodies  >1 publications with CDK19 and Brain
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