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NTF2-Related Export Protein 1 (NXT1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1301796

This protein is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region… More details

$785 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NTF2-related export protein 1 (NXT1), Recombinant Protein
Full Product Name
Recombinant Human NTF2-related export protein 1 (NXT1)
Product Gene Name
NXT1 recombinant protein
Product Synonym Gene Name
NXT1
Sequence
ASVDFKTYVD QACRAAEEFV NVYYTTMDKR RRLLSRLYMG TATLVWNGNA VSGQESLSEF FEMLPSSEFQ ISVVDCQPVH DEATPSQTTV LVVICGSVKF EGNKQRDFNQ NFILTAQASP SNTVWKIASD CFRFQDWAS
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
15,847 Da
Sequence Positions
2-140, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
605811
3D Structure
ModBase 3D Structure for Q9UKK6
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of NXT1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NXT1 purchase

MBS1301796 is a recombinant protein targeting NXT1. Also known as Recombinant Human NTF2-related export protein 1 (NXT1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.

Additional Details

NCBI/Uniprot data below describe general gene information for NXT1. It may not necessarily be applicable to this product.

NCBI GI #
7019471
NCBI GeneID
29107
NCBI Accession #
NP_037380.1
UniProt Primary Accession #
Q9UKK6
UniProt Related Accession #
Q9UKK6
GenBank Nucleotide #
NM_013248.2
NCBI Official Full Name
NTF2-related export protein 1
NCBI Official Synonym Full Names
nuclear transport factor 2 like export factor 1
NCBI Official Symbol
NXT1
NCBI Official Synonym Symbols
P15; MTR2
UniProt Protein Name
NTF2-related export protein 1
UniProt Synonym Protein Names
Protein p15
Protein Family
NTF2-related export protein
UniProt Gene Name
NXT1
NCBI Protein Information
NTF2-related export protein 1

NCBI Summary for NXT1

The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for NXT1

Stimulator of protein export for NES-containing proteins. Also plays a role in the nuclear export of U1 snRNA, tRNA, and mRNA. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5.

Research Articles on NXT1

1. Here, the authors identify cellular nuclear transport factor 2 (NTF2)-like export protein 1 (NXT1) as a novel binding partner of nucleoprotein (NP) that stimulates NP-mediated nuclear export via the CRM1-dependent pathway.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with NXT1 recombinant protein

 Reference Product  PubMed Publications
 NXF1 recombinant protein  >17 publications with NXT1 and NXF1
 NXF2 recombinant protein  >3 publications with NXT1 and NXF2
 NXF3 recombinant protein  >2 publications with NXT1 and NXF3
 NUP62 recombinant protein  >1 publications with NXT1 and NUP62
 NUP98 recombinant protein  >1 publications with NXT1 and NUP98

Pathways associated with NXT1 recombinant protein

 Products by Pathway  Pathway Diagram
 Exon Junction Complex (EJC) Pathway antibodies  Exon Junction Complex (EJC) Pathway Diagram
 Exon Junction Complex (EJC) Pathway antibodies  Exon Junction Complex (EJC) Pathway Diagram
 Influenza A Pathway antibodies  Influenza A Pathway Diagram
 Influenza A Pathway antibodies  Influenza A Pathway Diagram
 RNA Transport Pathway antibodies  RNA Transport Pathway Diagram
 RNA Transport Pathway antibodies  RNA Transport Pathway Diagram
 Ribosome Biogenesis In Eukaryotes Pathway antibodies  Ribosome Biogenesis In Eukaryotes Pathway Diagram
 Ribosome Biogenesis In Eukaryotes Pathway antibodies  Ribosome Biogenesis In Eukaryotes Pathway Diagram
 MRNA Surveillance Pathway antibodies  MRNA Surveillance Pathway Diagram
 MRNA Surveillance Pathway antibodies  MRNA Surveillance Pathway Diagram

Diseases associated with NXT1 recombinant protein

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >2 publications with NXT1 and Necrosis
 Inflammation Antibodies  >1 publications with NXT1 and Inflammation

Organs/Tissues associated with NXT1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >1 publications with NXT1 and Bone
 Brain Antibodies  >1 publications with NXT1 and Brain
 Spleen Antibodies  >1 publications with NXT1 and Spleen
 Testis Antibodies  >1 publications with NXT1 and Testis
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