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DNA-Binding Protein Inhibitor Id-3-A (id3-a) Xenopus Laevis Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1304234

MBS1304234 is a recombinant protein targeting id3-a. Also known as Recombinant Xenopus laevis DNA-binding protein inhibitor ID-3-A (id3-a). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$745 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DNA-binding protein inhibitor ID-3-A (id3-a), Recombinant Protein
Full Product Name
Recombinant Xenopus laevis DNA-binding protein inhibitor ID-3-A (id3-a)
Product Gene Name
id3-a recombinant protein
Product Synonym Gene Name
id3-a
Sequence
MKAISPVRSM SSCYQAVCCL SEQSLSIARG SSHKGPGMDE PMGLLYDMNG CYSKLKELVP GIPQGSKLSQ VEILQHVIDY IFDLQIVLGE DQQQSSILSL QKSDFSELAT QGDTSVCH
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
12,857 Da
Sequence Positions
1-118, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q91399
Species
Xenopus laevis (African clawed frog)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of id3-a recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for id3-a. It may not necessarily be applicable to this product.

NCBI GI #
147899694
NCBI GeneID
379222
NCBI Accession #
NP_001079535.1
UniProt Primary Accession #
Q91399
UniProt Secondary Accession #
Q91417
UniProt Related Accession #
Q91399
GenBank Nucleotide #
NM_001086066.1
NCBI Official Full Name
DNA-binding protein inhibitor ID-3-A
NCBI Official Synonym Full Names
inhibitor of DNA binding 3, HLH protein L homeolog
NCBI Official Symbol
id3.L
NCBI Official Synonym Symbols
id3; XId3; XIdI; XIdx; XIdIa; XIdIb; id3-a; id3-b; heir-1
UniProt Protein Name
DNA-binding protein inhibitor ID-3-A
UniProt Synonym Protein Names
Inhibitor of DNA binding 3
Protein Family
DNA-binding protein inhibitor
UniProt Gene Name
id3-a
UniProt Synonym Gene Names
; XIdx
NCBI Protein Information
DNA-binding protein inhibitor ID-3-A

UniProt Comments for id3-a

Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Influences cell fate decisions in the embryo by sequestering and blocking the activity of the bHLH transcription factors that control these decisions. Inhibits the binding of myogenic bHLH-containing complexes to E-box DNA, thereby preventing activation of muscle-specific target genes. Also inhibits the activity of neurogenic factor neurod1/neuroD. Plays a role in cell cycle progression and survival of neural crest progenitors; binding to either hes4-B/hairy2b or stat3 blocks the formation of transcription factor complexes and the repressor function of hes4-B/hairy2B, to allow neural crest progenitors to differentiate. May play a role in the regulation of the circadian rhythm.
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Research Articles on id3-a

1. Xenopus Id3 is required downstream of Myc for the formation of multipotent neural crest progenitor cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with id3-a recombinant protein

 Products by Pathway  Pathway Diagram
 TGF-beta Signaling Pathway antibodies  TGF-beta Signaling Pathway Diagram
 TGF-beta Signaling Pathway antibodies  TGF-beta Signaling Pathway Diagram

Organs/Tissues associated with id3-a recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >96 publications with id3-a and Bone
 Brain Antibodies  >52 publications with id3-a and Brain
 Thymus Antibodies  >28 publications with id3-a and Thymus
 Kidney Antibodies  >22 publications with id3-a and Kidney
 Testis Antibodies  >7 publications with id3-a and Testis
 Ectoderm Antibodies  >6 publications with id3-a and Ectoderm
 Whole Body Antibodies  >1 publications with id3-a and Whole Body
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