• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

Regulatory Solute Carrier Protein Family 1 Member 1 (RSC1A1) Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1306143

MBS1306143 is a recombinant protein targeting RSC1A1. Also known as Recombinant Human Regulatory solute carrier protein family 1 member 1 (RSC1A1). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$1425 / 0.02 mg (E-Coli) +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Regulatory solute carrier protein family 1 member 1 (RSC1A1), Recombinant Protein
Full Product Name
Recombinant Human Regulatory solute carrier protein family 1 member 1 (RSC1A1)
Product Gene Name
RSC1A1 recombinant protein
Product Synonym Gene Name
RSC1A1
Sequence
MSSLPTSDGF NHPARSSGQS PDVGNPMSLA RSVSASVCPI KPSDSDRIEP KAVKALKASA EFQLNSEKKE HLSLQDLSDH ASSADHAPTD QSPAMPMQNS SEEITVAGNL EKSAERSTQG LKFHLHTRQE ASLSVTSTRM HEPQMFLGEK DWHPENQNLS QVSDPQQHEE PGNEQYEVAQ QKASHDQEYL CNIGDLELPE ERQQNQHKIV DLEATMKGNG LPQNVDPPSA KKSIPSSECS GCSNSETFME IDTAQQSLVT LLNSTGRQNA NVKNIGALDL TLDNPLMEVE TSKCNPSSEI LNDSISTQDL QPPETNVEIP GTNKEYGHYS SPSLCGSCQP SVESAEESCP SITAALKELH ELLVVSSKPA SENTSEEVIC QSETIAEGQT SIKDLSERWT QNEHLTQNEQ CPQVSFHQAI SVSVETEKLT GTSSDTGREA VENVNFRSLG DGLSTDKEGV PKSRESINKN RSVTVTSAKT SNQLHCTLGV EISPKLLAGE EDALNQTSEQ TKSLSSNFIL VKDLGQGIQN SVTDRPETRE NVCPDASRPL LEYEPPTSHP SSSPAILPPL IFPATDIDRI LRAGFTLQEA LGALHRVGGN ADLALLVLLA KNIVVPT
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
66,790 Da
Sequence Positions
1-617, Full length protein
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
601966
3D Structure
ModBase 3D Structure for Q92681
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of RSC1A1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RSC1A1. It may not necessarily be applicable to this product.

NCBI GI #
5730021
NCBI GeneID
6248
NCBI Accession #
NP_006502.1
UniProt Primary Accession #
Q92681
UniProt Secondary Accession #
B2RBP5
UniProt Related Accession #
Q92681
GenBank Nucleotide #
NM_006511.2
NCBI Official Full Name
regulatory solute carrier protein family 1 member 1
NCBI Official Synonym Full Names
regulator of solute carriers 1
NCBI Official Symbol
RSC1A1
NCBI Official Synonym Symbols
RS1
UniProt Protein Name
Regulatory solute carrier protein family 1 member 1
UniProt Synonym Protein Names
Transporter regulator RS1; hRS1
Protein Family
Regulatory solute carrier protein family
UniProt Gene Name
RSC1A1
UniProt Synonym Gene Names
hRS1
NCBI Protein Information
regulatory solute carrier protein family 1 member 1

NCBI Summary for RSC1A1

The protein encoded by this intronless gene inhibits the expression of the solute carrier family 5 (sodium/glucose cotransporter), member 1 gene (SLC5A1) and downregulates exocytosis of the SLC5A1 protein. The encoded protein is sometimes found coating the trans-Golgi network and other times is localized to the nucleus, depending on the cell cycle stage. This protein also inhibits the expression of solute carrier family 22 (organic cation transporter), member 2 (SLC22A2). [provided by RefSeq, Dec 2015]
Show more

UniProt Comments for RSC1A1

Mediates transcriptional and post-transcriptional regulation of SLC5A1. Inhibits a dynamin and PKC-dependent exocytotic pathway of SLC5A1. Also involved in transcriptional regulation of SLC22A2. Exhibits glucose-dependent, short-term inhibition of SLC5A1 and SLC22A2 by inhibiting the release of vesicles from the trans-Golgi network.
Show more

Research Articles on RSC1A1

1. Binding of RS1-Reg to ODC1 inhibits the enzymatic activity at low intracellular glucose, which is blunted at high intracellular glucose.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with RSC1A1 recombinant protein

 Reference Product  PubMed Publications
 SLC22A2 recombinant protein  >1 publications with RSC1A1 and SLC22A2

Diseases associated with RSC1A1 recombinant protein

 Disease Name  Pubmed Publications
 Obesity Antibodies  >2 publications with RSC1A1 and Obesity

Organs/Tissues associated with RSC1A1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >4 publications with RSC1A1 and Intestine
 Kidney Antibodies  >3 publications with RSC1A1 and Kidney
 Liver Antibodies  >2 publications with RSC1A1 and Liver
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000